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HOME > Product search results > Code No. PD014 Anti-LC3 pAb

Code No. PD014

Anti-LC3 pAb

Price

¥42,000

Availability (in Japan)

10 or more

(In Japan at 00:05,
Nov 14, 2019 in JST)

Size

100 µL

Data
  • Western Blotting

Clonality Polyclonal Clone Polyclonal
Isotype (Immunized Animal) Rabbit IgG
Applications
WB
1:1,000  
IC*
reported  (PMID: 20392947 / 20559548
IH*
reported  (PMID: 18190792 / 19907114
Immunogen (Antigen) Recombinant full-length Rat LC3
Reactivity [Gene ID]

Human[81631], Mouse[67443], Rat[64862], Hamster

Storage buffer PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names microtubule-associated protein 1 light chain 3 beta, LC3B, ATG8F, MAP1LC3B-a, MAP1A/1BLC3, MAP1LC3B
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Citations

Western Blotting

  1. Takamura A et al. Enhanced autophagy and mitochondrial aberrations in murine G(M1)-gangliosidosis. Biochem Biophys Res Commun. 367, 616-22 (2008)(PMID:18190792)
  2. Wong HK et al. Blocking acid-sensing ion channel 1 alleviates Huntington's disease pathology via an ubiquitin-proteasome system-dependent mechanism. Hum Mol Genet. 17, 3223-35 (2008)(PMID:18658163)
  3. Maycotte P et al. Apoptosis and autophagy in rat cerebellar granule neuron death: Role of reactive oxygen species. J Neurosci Res. 88, 73-85 (2010)(PMID:19598251)
  4. Vazquez-Martin A et al. Autophagy facilitates the development of breast cancer resistance to the anti-HER2 monoclonal antibody trastuzumab. PLoS One. 4, e6251 (2009)(PMID:19606230)
  5. Rouschop KM et al. Autophagy is required during cycling hypoxia to lower production of reactive oxygen species. Radiother Oncol. 92, 411-6 (2009)(PMID:19616335)
  6. Otomo T et al. Inhibition of autophagosome formation restores mitochondrial function in mucolipidosis II and III skin fibroblasts. Mol Genet Metab. 98, 393-9 (2009)(PMID:19656701)
  7. Vega-Naredo I et al. Sexual dimorphism of autophagy in Syrian hamster Harderian gland culminates in a holocrine secretion in female glands. Autophagy 5, 1004-17 (2009)(PMID:19736526)
  8. Rouschop KM et al. The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5. J Clin Invest. 120, 127-41 (2010)(PMID:20038797)
  9. Jaeger PA et al. Regulation of amyloid precursor protein processing by the Beclin 1 complex. PLoS One 5, e11102 (2010)(PMID:20559548)
  10. Hou W et al. Autophagic degradation of active caspase-8: a crosstalk mechanism between autophagy and apoptosis. Autophagy 6, 891-900 (2010)(PMID:20724831)
  11. Hariharan N et al. Oxidative stress stimulates autophagic flux during ischemia/reperfusion. Antioxid Redox Signal. 14, 2179-90 (2011)(PMID:20812860)
  12. O'Donovan TR et al. Induction of autophagy by drug-resistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics. Autophagy 7, 509-24 (2011)(PMID:21325880)
  13. Kurz T et al. Cell sensitivity to oxidative stress is influenced by ferritin autophagy. Free Radic Biol Med. 50, 1647-58 (2011)(PMID:21419217)
  14. Kim JH et al. Involvement of mitophagy in oncogenic K-Ras-induced transformation: overcoming a cellular energy deficit from glucose deficiency. Autophagy 7, 1187-98 (2011)(PMID:21738012)
  15. Son YO et al. Cadmium induces autophagy through ROS-dependent activation of the LKB1-AMPK signaling in skin epidermal cells. Toxicol Appl Pharmacol. 255, 287-96 (2011)(PMID:21767558)
  16. Vega-Naredo I et al. Melatonin modulates autophagy through a redox-mediated action in female Syrian hamster Harderian gland controlling cell types and gland activity. J Pineal Res. 52, 80-92 (2012)(PMID:21771054)
  17. Cui D et al. Propofol prevents autophagic cell death following oxygen and glucose deprivation in PC12 cells and cerebral ischemia-reperfusion injury in rats. PLoS One 7, e35324 (2012)(PMID:22509406)
  18. Tsuchiya Y et al. The casein kinase 2-nrf1 axis controls the clearance of ubiquitinated proteins by regulating proteasome gene expression. Mol Cell Biol. 33, 3461-72 (2013)(PMID:23816881)
  19. Bermejo-Millo JC et al. High-Fructose Consumption Impairs the Redox System and Protein Quality Control in the Brain of Syrian Hamsters: Therapeutic Effects of Melatonin. Mol Neurobiol.(2018) In press.(PMID:29492847)
  20. Moruno-Manchon JF et al. Sphingosine kinase 1-associated autophagy differs between neurons and astrocytes. Cell Death Dis. 9, 521 (2018)(PMID:29743513)

Immunocytochemistry

  1. Brown JE et al. Essential role of the redox-sensitive kinase p66shc in determining energetic and oxidative status and cell fate in neuronal preconditioning. J Neurosci. 30, 5242-52 (2010)(PMID:20392947)
  2. Jaeger PA et al. Regulation of amyloid precursor protein processing by the Beclin 1 complex. PLoS One 5, e11102 (2010)(PMID:20559548)
  3. Kobayashi S et al. BAF is a cytosolic DNA sensor that leads to exogenous DNA avoiding autophagy. PNAS 112, 7027-32 (2015)(PMID:25991860)

Immunohistochemistry

  1. Takamura A et al. Enhanced autophagy and mitochondrial aberrations in murine G(M1)-gangliosidosis. Biochem Biophys Res Commun. 367, 616-22 (2008)(PMID:18190792)
  2. Wang J et al. Possible role for external environmental stimuli in nasopharyngeal NK/T-cell lymphomas in the northeast of China with EBV infection-related autophagic cell death: a pathoepidemiological analysis. J Clin Exp Hematop. 49, 97-108 (2009)(PMID:19907114)
Product category
Research area
Autophagy
Brands
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  • The availability is based on the information in Japan at 00:05, Nov 14, 2019 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.