| Code No. |
PD014 |
|
Anti-LC3 pAb
|
| Price |
¥48,600
|
| Size |
100 µL |
| Availability (in Japan) |
10 or more
(In Japan at 00:05, May 21, 2026 in JST)
|
| Clonality |
Polyclonal |
| Clone |
Polyclonal |
Isotype
(Immunized Animal) |
Rabbit IgG |
| Applications |
WB 1:1,000 IC* reported (PMID: 20392947 / 20559548) IH* reported (PMID: 18190792 / 19907114)
|
Immunogen
(Antigen) |
Recombinant full-length Rat LC3 |
| Reactivity [Gene ID] |
Human[81631], Mouse[67443], Rat[64862], Hamster |
| Storage buffer |
"PBS/50% glycerol, pH 7.2" |
| Storage temp. |
-20°C |
| Conjugate |
Unlabeled |
| Manufacturer |
MBL |
| Alternative names |
"microtubule-associated protein 1 light chain 3 beta, LC3B, ATG8F, MAP1LC3B-a, MAP1A/1BLC3, MAP1LC3B" |
| Related products |
PM036 Anti-LC3 pAb M152-3 Anti-LC3 mAb M186-3 Anti-LC3 mAb PM045 Anti-p62 (SQSTM1) pAb M162-3 Anti-p62 (SQSTM1) (Human) mAb PM072 Anti-VMP1 pAb PM066 Anti-p62 C-terminal pAb PD017 Anti-Beclin 1 pAb PM037 Anti-GABARAP pAb M135-3 Anti-GABARAP mAb PM038 Anti-GATE-16 pAb 8485 Autophagy Ab Sampler Set PM039 Anti-Atg7 (Human) pAb PM036-PN Positive control for anti-LC3 antibody M133-3 Anti-Atg3 mAb 8486 Autophagy Watch PM090 Anti-Atg8 (Filamentous fungi) pAb M152-3MS Anti-LC3 mAb for My select sampler set M134-3 Anti-Atg4B mAb M154-3 Anti-Atg12 (Human) mAb M162-A48 Anti-p62 (SQSTM1) (Human) mAb-Alexa Fluor™ 488 M162-A59 Anti-p62 (SQSTM1) (Human) mAb-Alexa Fluor™ 594 M162-A64 Anti-p62 (SQSTM1) (Human) mAb-Alexa Fluor™ 647 M186-7 Anti-LC3 mAb-HRP-DirecT
|
| Product category |
Research area:Autophagy |
| Data |

|
| Citations |
Western Blotting - Takamura A et al. Enhanced autophagy and mitochondrial aberrations in murine G(M1)-gangliosidosis. Biochem Biophys Res Commun. 367, 616-22 (2008)(PMID:18190792)
- Wong HK et al. Blocking acid-sensing ion channel 1 alleviates Huntington's disease pathology via an ubiquitin-proteasome system-dependent mechanism. Hum Mol Genet. 17, 3223-35 (2008)(PMID:18658163)
- Maycotte P et al. Apoptosis and autophagy in rat cerebellar granule neuron death: Role of reactive oxygen species. J Neurosci Res. 88, 73-85 (2010)(PMID:19598251)
- Vazquez-Martin A et al. Autophagy facilitates the development of breast cancer resistance to the anti-HER2 monoclonal antibody trastuzumab. PLoS One. 4, e6251 (2009)(PMID:19606230)
- Rouschop KM et al. Autophagy is required during cycling hypoxia to lower production of reactive oxygen species. Radiother Oncol. 92, 411-6 (2009)(PMID:19616335)
- Otomo T et al. Inhibition of autophagosome formation restores mitochondrial function in mucolipidosis II and III skin fibroblasts. Mol Genet Metab. 98, 393-9 (2009)(PMID:19656701)
- Vega-Naredo I et al. Sexual dimorphism of autophagy in Syrian hamster Harderian gland culminates in a holocrine secretion in female glands. Autophagy 5, 1004-17 (2009)(PMID:19736526)
- Rouschop KM et al. The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5. J Clin Invest. 120, 127-41 (2010)(PMID:20038797)
- Jaeger PA et al. Regulation of amyloid precursor protein processing by the Beclin 1 complex. PLoS One 5, e11102 (2010)(PMID:20559548)
- Hou W et al. Autophagic degradation of active caspase-8: a crosstalk mechanism between autophagy and apoptosis. Autophagy 6, 891-900 (2010)(PMID:20724831)
- Hariharan N et al. Oxidative stress stimulates autophagic flux during ischemia/reperfusion. Antioxid Redox Signal. 14, 2179-90 (2011)(PMID:20812860)
- O'Donovan TR et al. Induction of autophagy by drug-resistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics. Autophagy 7, 509-24 (2011)(PMID:21325880)
- Kurz T et al. Cell sensitivity to oxidative stress is influenced by ferritin autophagy. Free Radic Biol Med. 50, 1647-58 (2011)(PMID:21419217)
- Kim JH et al. Involvement of mitophagy in oncogenic K-Ras-induced transformation: overcoming a cellular energy deficit from glucose deficiency. Autophagy 7, 1187-98 (2011)(PMID:21738012)
- Son YO et al. Cadmium induces autophagy through ROS-dependent activation of the LKB1-AMPK signaling in skin epidermal cells. Toxicol Appl Pharmacol. 255, 287-96 (2011)(PMID:21767558)
- Vega-Naredo I et al. Melatonin modulates autophagy through a redox-mediated action in female Syrian hamster Harderian gland controlling cell types and gland activity. J Pineal Res. 52, 80-92 (2012)(PMID:21771054)
- Cui D et al. Propofol prevents autophagic cell death following oxygen and glucose deprivation in PC12 cells and cerebral ischemia-reperfusion injury in rats. PLoS One 7, e35324 (2012)(PMID:22509406)
- Tsuchiya Y et al. The casein kinase 2-nrf1 axis controls the clearance of ubiquitinated proteins by regulating proteasome gene expression. Mol Cell Biol. 33, 3461-72 (2013)(PMID:23816881)
- Bermejo-Millo JC et al. High-Fructose Consumption Impairs the Redox System and Protein Quality Control in the Brain of Syrian Hamsters: Therapeutic Effects of Melatonin. Mol Neurobiol.(2018) In press.(PMID:29492847)
- Moruno-Manchon JF et al. Sphingosine kinase 1-associated autophagy differs between neurons and astrocytes. Cell Death Dis. 9, 521 (2018)(PMID:29743513)
- Shen J et al. Role of Autophagy in Zinc Oxide Nanoparticles-Induced Apoptosis of Mouse LEYDIG Cells. Int J Mol Sci. 20, pii: E4042 (2019)(PMID:31430870)
- Moreno-Blas D et al. Cortical neurons develop a senescence-like phenotype promoted by dysfunctional autophagy. Aging (Albany NY). 11, 6175-6198 (2019)(PMID:31469660)
- Jiang LJ et al. Resatorvid Protects Against Hypoxic-Ischemic Brain Damage in Neonatal Rats. Neural Regen Res. 15, 1316-1325 (2020)(PMID:31960818)
Immunocytochemistry - Brown JE et al. Essential role of the redox-sensitive kinase p66shc in determining energetic and oxidative status and cell fate in neuronal preconditioning. J Neurosci. 30, 5242-52 (2010)(PMID:20392947)
- Jaeger PA et al. Regulation of amyloid precursor protein processing by the Beclin 1 complex. PLoS One 5, e11102 (2010)(PMID:20559548)
- Kobayashi S et al. BAF is a cytosolic DNA sensor that leads to exogenous DNA avoiding autophagy. PNAS 112, 7027-32 (2015)(PMID:25991860)
Immunohistochemistry - Takamura A et al. Enhanced autophagy and mitochondrial aberrations in murine G(M1)-gangliosidosis. Biochem Biophys Res Commun. 367, 616-22 (2008)(PMID:18190792)
- Wang J et al. Possible role for external environmental stimuli in nasopharyngeal NK/T-cell lymphomas in the northeast of China with EBV infection-related autophagic cell death: a pathoepidemiological analysis. J Clin Exp Hematop. 49, 97-108 (2009)(PMID:19907114)
Other - Moreno-Blas D et al. Cortical neurons develop a senescence-like phenotype promoted by dysfunctional autophagy. Aging (Albany NY). 11, 6175-6198 (2019)(PMID:31469660)
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