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エピジェネティクス


CycLex® Cellular Histone Acetylation Assay Kit
  1. Venturelli S et al. Resveratrol as a pan-HDAC inhibitor alters the acetylation status of histone proteins in human-derived hepatoblastoma cells. PLoS One. 8, e73097 (2013)(PMID:24023672
  1. Nishino T et al. Ex vivo expansion of human hematopoietic stem cells by garcinol, a potent inhibitor of histone acetyltransferase. PLoS One. 6, e24298 (2011)(PMID:21931675
  1. Reed K et al. The temporal relationship between ABCB1 promoter hypomethylation, ABCB1 expression and acquisition of drug resistance. Pharmacogenomics J. 10, 489-504 (2010)(PMID:20125118
CycLex® SIRT3 Deacetylase Fluorometric Assay Kit Ver.2
※Cyclex® SIRT3 Deacetylase Fluoromeric Assay Kit (Code No. CY-1153)の後継品です。
  1. Wang Q et al. SIRT3 protects cells from hypoxia via PGC-1α- and MnSOD-dependent pathways. 286, 109-21 (2015)(PMID:25433241
  1. Shulga N and Pastorino JG. Hexokinase II binding to mitochondria is necessary for Kupffer cell activation and is potentiated by ethanol exposure. J Biol Chem. 289, 26213-25 (2014)(PMID:25096575
  1. Zhuge CC et al. Fullerenol protects retinal pigment epithelial cells from oxidative stress-induced premature senescence via activating SIRT1. Invest Ophthalmol Vis Sci. 55, 4628-38 (2014)(PMID:24845634

CycLex® SIRT1/Sir2 Deacetylase Fluorometric Assay Kit Ver.2
  1. Kayashima Y et al. Alkylresorcinols activate SIRT1 and delay ageing in Drosophila melanogaster. Sci Rep. 7, 43679 (2017)(PMID:28252007

※CycLex® SIRT1/Sir2 Deacetylase Fluorometric Assay Kit(Code No. CY-1151)の後継品です。
  1. Pang J et al. Effect of NAD on PARP-mediated insulin sensitivity in oleic acid treated hepatocytes. J Cell Physiol. 230, 1607-13 (2015)(PMID:25536389
  1. Li D et al. A novel crosstalk between BRCA1 and sirtuin 1 in ovarian cancer. Sci Rep. 4, 6666 (2014)(PMID:25323003
  1. Hsu CY and Hu TH. Energy-regulated molecules maintain young status in the trophocytes and fat cells of old queen honeybees. Biogerontology. 15, 389-400 (2014)(PMID:24973265

CycLex® HDACs Deacetylase Fluorometric Assay Kit Ver.2
※CycLex® HDACs Deacetylase Fluorometric Assay Kit(Code No. CY-1150)の後継品です。
  1. Ishiai S et al. Histone deacetylase inhibitory effect of Brazilian propolis and its association with the antitumor effect in Neuro2a cells. Food Sci Nutr. 2, 565-70 (2014)(PMID:25473514
  1. Suzuki T et al. Design, Synthesis, and Biological Activity of NCC149 Derivatives as Histone Deacetylase 8 Selective Inhibitors ChemMedChem. 9, 657-64 (2014)(PMID:24403121
  1. Suzuki T et al. Identification of highly selective and potent histone deacetylase 3 inhibitors using click chemistry-based combinatorial fragment assembly. PLoS One. 8, e68669 (2013)(PMID:23874714



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