Code No. |
Product name |
Synonyms |
Reactivity |
Applications |
Function, localization |
RN001M |
Anti-IGF2BP1 (IMP1) mAb |
IMP1, ZBP1 |
Hu/ Mo |
WB/ IP/ RIP |
IGF2BP1 represses translation initiation of β-actin mRNA via binding to it in nucleus and translocates to cytoplasm. When localized to destination in cytoplasm, IGF2BP1 bound to the mRNA is released from it by phosphorylation to intiate translation. |
RN007P |
Anti-IGF2BP1 (IMP1) pAb |
IMP1, ZBP1 |
Hu/ Mo |
WB/ IP/ RIP/ IC/ IF |
IGF2BP1 represses translation initiation of β-actin mRNA via binding to it in nucleus and translocates to cytoplasm. When localized to destination in cytoplasm, IGF2BP1 bound to the mRNA is released from it by phosphorylation to intiate translation. |
RN008P |
Anti-IGF2BP2 (IMP2) pAb |
IMP2 |
Hu/ Mo/ Rat |
WB/ IP/ RIP/ IC/ IF |
IGF2BP2 binds to the UTR of IGF2 leader 3 mRNA, which is related to development and proliferation, and regulates its translation. |
RN009P |
Anti-IGF2BP3 (IMP3) pAb |
IMP3 |
Hu/ Mo |
WB/ IP/ RIP |
IGF2BP3 binds to the 5'-UTR of IGF2 leader 3 mRNA, which is related to development and proliferation, and regulates its translation. |
RN077PW |
Anti-SMN1 pAb |
|
Hu |
WB/ IP/ IC |
SMN1 regulates the localization of poly(A) RNA through interaction with HuD in mouse neuronal cell. |
RN012P |
Anti-STAU1 (Human) pAb |
|
Hu |
WB/ IP/ RIP |
STAU1, forms RNA granule in neuronal cells. It is reported that STAU1 regulates export and localization of mRNA via binding to dsRNAs and microtubles. It is also related to SMD (Staufen-Mediated mRNA Decay) and assembly of 40S and 60S ribosomal subunits. |
RN013P |
Anti-STAU2 (Human) pAb |
|
Hu |
WB/ IP/ RIP |
STAU2 is highly homologous to STAU1, but their functions may be different because they do not co-localize in neuronal cells. STAU2 shuttles between nucleus and cytoplasm, however, the function in detail is unknown. |