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HOME > Product search results > Code No. D363-3 Anti-Ly6k (Mouse) mAb

Code No.　D363-3

Anti-Ly6k (Mouse) mAb

Price

¥52,800

Availability (in Japan)

10 or more

（In Japan at 17:00,
Feb 16, 2025 in JST）

Size

100 µL (1 mg/mL)

Related information
・Rat IgG2a (isotype control)
Data

  • Western Blotting

    non-reducing condition

  • Immunoprecipitation

  • Flow Cytometry
Clonality Monoclonal Clone mk34
Isotype (Immunized Animal) Rat IgG2aκ
Applications
WB
1 μg/mL  
IP
15 μg/sample  
FCM
1 μg/mL  
IH*
reported.  （PMID: 20920470 / 27005865）
Immunogen (Antigen) Mouse testicular water-insoluble fraction
Reactivity [Gene ID]

Human**, Mouse[76486], Rat**
Storage buffer 1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names mLy-6K,  lymphocyte antigen 6 complex, locus K
Background Ly6k（lymphocyte antigen 6 complex, locus K）は主に精巣で発現しているGPIアンカー型タンパク質です。同じくGPIアンカー型タンパク質であるTex101（Testis expressed gene 101）と複合体を形成することが知られています。Tex101またはLy6kをそれぞれ欠損させた精子は、形態や運動性の面では正常であり、体外受精は可能ですが、生体内においては子宮から卵管に移行することができず不妊となることから、Tex101/Ly6k複合体は精子の受精能獲得に重要な働きをしていると考えられています。
Related products D357-3 Anti-Ace (CD143) (Mouse) mAb
M207-3 Anti-MitoPLD (Pld6) mAb
PM044 Anti-PIWIL2 (MILI) (Mouse) pAb
D365-3 Anti-PIWIL2 (MILI) (Mouse) mAb
References
  1. Endo S et al. TEX101, a glycoprotein essential for sperm fertility, is required for stable expression of Ly6k on testicular germ cells. Sci Rep. 6, 23616 (2016)（PMID: 27005865）
  2. Maruyama M et al. Molecular expression of Ly6k, a putative glycosylphosphatidyl-inositol-anchored membrane protein on the mouse testicular germ cells. Biochem Biophys Res Commun. 402, 75-81 (2010)（PMID: 20920470）
  3. Yoshitake H et al. TEX101, a germ cell-marker glycoprotein, is associated with lymphocyte antigen 6 complex locus k within the mouse testis. Biochem Biophys Res Commun. 372, 277-82 (2008)（PMID: 18503752）
  4. Tsukamoto H et al. Testicular proteins associated with the germ cell-marker, TEX101: involvement of cellubrevin in TEX101-trafficking to the cell surface during spermatogenesis. Biochem Biophys Res Commun. 345, 229-38 (2006)（PMID: 16678124）
Product category
Research area
Stem cell research
Cancer
この製品に関するお問い合わせをする

  • The availability is based on the information in Japan at 17:00, Feb 16, 2025 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications：
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.