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HOME > Product search results > Code No. M212-3 Anti-Syntaxin-17 (Human) mAb

Code No. M212-3

Anti-Syntaxin-17 (Human) mAb

Price

¥48,000

Availability (in Japan)

10 or more

(In Japan at 00:05,
Jul 30, 2021 in JST)

Size

100 µg/100 µL

Data
  • Western Blotting

  • Immunoprecipitation

Clonality Monoclonal Clone 2F8
Isotype (Immunized Animal) Mouse IgG2aκ
Applications
WB
1 µg/mL  
IP
2 µg/sample  
IC*
reported.  (PMID: 29290589
Immunogen (Antigen) Human Syntaxin-17, recombinant protein
Reactivity [Gene ID]

Human[55014], Mouse(-), Rat(-), Hamster(-)

Storage buffer 1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Background Syntaxin 17 (Stx17) is the autophagosomal SNARE protein required for fusion with the endosome/lysosome. Stx17 localizes to the completed autophagosomes but not to the isolation membrane. Stx17 is essential for its selective targeting to the outer autophagosomal membrane and available to the completed autophagosome.
Related products PM076 Anti-Syntaxin-17 (Human) pAb
M212-3MS Anti-Syntaxin-17 (Human) mAb for My select sampler set
Citations

Western Blotting

  1. Yamashita SI et al. Mitochondrial division occurs concurrently with autophagosome formation but independently of Drp1 during mitophagy. J Cell Biol. 215, 649-665 (2016)(PMID:27903607)

Immunocytochemistry

  1. Smith MD et al. CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis. Dev Cell. 44, 217-232.e11 (2018)(PMID:29290589)
References
  1. Hamasaki M et al. Autophagosomes form at ER-mitochondria contact sites. Nature 495, 389-93 (2013)(PMID: 23455425
  2. Itakura E et al. The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes. Cell 151, 1256-69 (2012)(PMID: 23217709
Product category
Research area
Autophagy
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  • The availability is based on the information in Japan at 00:05, Jul 30, 2021 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.