Antibody detailed product information

Code No. M212-3 プリントPrint out
Anti-Syntaxin-17 (Human) mAb
Price ¥48,000
Size 100 µg/100 µL
Availability (in Japan) 10 or more
(In Japan at 00:05, Sep 17, 2021 in JST)
Clonality Monoclonal
Clone 2F8
Isotype
(Immunized Animal)
Mouse IgG2aκ
Applications WB 1 µg/mL  
IP 2 µg/sample  
IC* reported.  (PMID: 29290589)
Immunogen
(Antigen)
Human Syntaxin-17, recombinant protein
Reactivity [Gene ID]

Human[55014], Mouse(-), Rat(-), Hamster(-)

Storage buffer 1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp. -20°C
Conjugate Unlabeled
Manufacturer MBL
Background Syntaxin 17 (Stx17) is the autophagosomal SNARE protein required for fusion with the endosome/lysosome. Stx17 localizes to the completed autophagosomes but not to the isolation membrane. Stx17 is essential for its selective targeting to the outer autophagosomal membrane and available to the completed autophagosome.
Related products PM076 Anti-Syntaxin-17 (Human) pAb
M212-3MS Anti-Syntaxin-17 (Human) mAb for My select sampler set
Product category Research area:Autophagy
Data


Citations

Western Blotting

  1. Yamashita SI et al. Mitochondrial division occurs concurrently with autophagosome formation but independently of Drp1 during mitophagy. J Cell Biol. 215, 649-665 (2016)(PMID:27903607)

Immunocytochemistry

  1. Smith MD et al. CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis. Dev Cell. 44, 217-232.e11 (2018)(PMID:29290589)
References
  1. Hamasaki M et al. Autophagosomes form at ER-mitochondria contact sites. Nature 495, 389-93 (2013)(PMID: 23455425
  2. Itakura E et al. The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes. Cell 151, 1256-69 (2012)(PMID: 23217709
  • The availability is based on the information in Japan at 00:05, Sep 17, 2021 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.
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