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HOME > Product search results > Code No. M161-3 Anti-IL-33 (Mouse) mAb

Code No. M161-3

Anti-IL-33 (Mouse) mAb



Availability (in Japan)


(In Japan at 17:00,
Aug 10, 2020 in JST)


100 µg/100 µL

  • Western Blotting

  • Immunoprecipitation

Clonality Monoclonal Clone 4G4
Isotype (Immunized Animal) Mouse IgG2aκ
1 µg/mL  
2 µg/sample  
Immunogen (Antigen) Recombinant protein corresponding to amino acid residues 109-266 of mouse IL-33
Reactivity [Gene ID]

Human(-), Mouse[77125], Rat(-)

Storage buffer 1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names interleukin 33, Il33
Background The Interleukin-1 (IL-1) family, such as IL-1a/b and IL-18, has important functions in host defense, immune regulation, and inflammation. IL-33, a member of the IL-1 family, that shows to induce T helper (Th) type 2 responses by signaling through the IL-1 receptor-related protein ST2 (IL-1R4), an orphan member of the IL-1 receptor family. Similarly to IL-1a/b and IL-18, IL-33 is synthesized as a 31 kDa precursor protein has been shown to be cleaved by caspase-1 in vitro. In vivo, IL-33 induces the expression of IL-4, IL-5, and IL-13 and leads to severe pathological changes in mucosal organs. IL-33 has been originally identified as NF-HEV, which is a nuclear factor preferentially expressed in high endothelial venules. IL-33 may function as both a proinflammatory cytokine and an intracellular nuclear factor involved in transcriptional regulation.
Related products M138-3 Anti-IL-33 (Human) mAb
M187-3 Anti-IL-33 (Mouse) mAb (Functional Grade)
M188-3 Anti-IL-33 (Mouse) mAb (Functional Grade)
PM033 Anti-IL-33 (Human) pAb
D358-3 Anti-IL-38 (IL1F10) (Human) mAb
D359-3 Anti-IL-38 (IL1F10) (Human) mAb

Western Blotting

  1. Ohno T et al. Caspase-1, caspase-8, and calpain are dispensable for IL-33 release by macrophages. J Immunol. 183, 7890-7 (2009)(PMID:19933859)
Product category
Research area
Cytokine & Growth Factors

  • The availability is based on the information in Japan at 17:00, Aug 10, 2020 in JST.
  • The special price is shown in red color.
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  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.