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HOME > Product search results > Code No. D133-3M2
Anti-CD279 (PD-1) (Human) mAb (Functional Grade)
Code No. D133-3M2
Anti-CD279 (PD-1) (Human) mAb (Functional Grade)
Price
¥79,200
Availability (in Japan)
10 or more
（In Japan at 00:05,
Jan 24, 2025 in JST）
Size
100 µL (1 mg/mL)
Data Sheet| Data |
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|---|---|---|---|---|---|
| Clonality | Monoclonal | Clone | J105 | ||
| Isotype (Immunized Animal) | Mouse IgG1 | ||||
| Applications |
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| Immunogen (Antigen) | Fc-fusion human PD-1 protein | ||||
| Reactivity [Gene ID] | Human[5133] |
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| Storage buffer | 1 mg/mL in PBS. Azide free, 0.22 μm sterile-filtered | ||||
| Storage temp. | -20°C | Conjugate | Unlabeled | Manufacturer | MBL |
| Alternative names | PDCD1, programmed cell death 1, PD1, SLEB2, hPD-1, hPD-l, hSLE1 | ||||
| Background | Human PD-1 (programmed death-1) is a 55 kDa member of the immunoglobulin superfamily that is induced in cells undergoing apoptosis. The PD-1 protein contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) and is expressed predominantly on activated T and B lymphocytes. PD-1 plays a key role in peripheral tolerance and autoimmune disease and is thought to be involved in the maintenance of peripheral self-tolerance by serving as a negative regulator of immune responses. Two novel members of the B7 family have been identified as PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and up-regulation on activated antigen-presenting cells. | ||||
| Related products | M075-3M2 Mouse IgG1 (isotype control) (Functional Grade) D133-3 Anti-CD279 (PD-1) (Human) mAb D133-5 Anti-CD279 (PD-1) (Human) mAb-PE D132-3 Anti-CD279 (PD-1) (Human) mAb D132-4 Anti-CD279 (PD-1) (Human) mAb-FITC D132-5 Anti-CD279 (PD-1) (Human) mAb-PE D092-3 Anti-CD274 (PD-L1) (Human) mAb D230-3 Anti-CD274 (PD-L1) (Human) mAb D230-5 Anti-CD274 (PD-L1) (Human) mAb-PE D092-3M2 Anti-CD274 (PD-L1) (Human) mAb (Functional Grade) |
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- The availability is based on the information in Japan at 00:05, Jan 24, 2025 in JST.
- The special price is shown in red color.
- Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
- Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization - For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
- For storage temparature: RT: room temparature
- Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.