Code No. U-R007-10
hRSPO1-his
価格（税別）
¥648,000
在庫
0
(お問合せ）
（2024/04/26 17:33時点）
包装
1.0 mg
データシートUse, storage and stability
Human RSPO1-his protein has been successfully used in various types of organoids like colon, ileum and duodenum organoids. The working concentration of the product in organoid cultures should be determined experimentally. As a starting concentration 10 – 20 nM can be used. Depending on the type of organoid 0.2 nM WNT surrogate-Fc fusion protein (catalog U-N001), or similar, can be added.
The product should be stored at -80°C. After thawing it should be stored in appropriate small aliquots at -20°C or -80°C (stable for at least 6 months) or at 4°C for 3 weeks.
Production platform:
This product has been produced in HEK293 cells using the rPExTM recombinant protein production platform.
datasheet url: https://products.ipatherapeutics.com/product/r007-1-0-mg/
Human RSPO1-his protein has been successfully used in various types of organoids like colon, ileum and duodenum organoids. The working concentration of the product in organoid cultures should be determined experimentally. As a starting concentration 10 – 20 nM can be used. Depending on the type of organoid 0.2 nM WNT surrogate-Fc fusion protein (catalog U-N001), or similar, can be added.
The product should be stored at -80°C. After thawing it should be stored in appropriate small aliquots at -20°C or -80°C (stable for at least 6 months) or at 4°C for 3 weeks.
Production platform:
This product has been produced in HEK293 cells using the rPExTM recombinant protein production platform.
datasheet url: https://products.ipatherapeutics.com/product/r007-1-0-mg/
| 使用目的 | stem cell culture; organoid | ||
|---|---|---|---|
| 保存温度 | -80°C | メーカー | ImmunoPrecise Antibodies (Europe) BV |
| 別称 | hRSPO1-his Protein, Human RPSO1-his, roof plate-specific spondin 1, Rspo1, R-spondin 1, Cristin 3 | ||
| 背景 | Description RSPO1 is a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt/β-catenin signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Although R-spondins are unable to initiate Wnt signaling, they can potently enhance responses to low-dose Wnt proteins. |
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| 備考 | オルガノイド等の培養において、本製品を他の因子との組合せで使用する場合、当該他の因子の使用等に第三者の特許が存在する可能性がございます。本製品は、他の因子との組合せによる使用等まで保証するものではございませんので、当該他の因子との組合せで使用する場合に関しては、ご所属の知財部・調査機関へご確認のうえ、本製品をご利用ください。 | ||
| 製品 カテゴリー |
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※保存温度の表記について： RT: 室温
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