Code No. U-H001-01
Recombinant human herstatin
価格（税別）
¥98,000
在庫
0
(お問合せ）
（2024/06/30 17:00時点）
包装
100 µg
データシートStorage and Stability:
HER2-ECD should be stored at - 80℃ (stable for at least 1 year). The buffer contains PBS without preservative. After thawing it should be stored in appropriate small aliquots at - 20℃ or - 80℃ (stable for at least 2 months).
Production platform:
HEK293 cells using the rPEx™ recombinant protein production platform.
データシートURL：
https://products.ipatherapeutics.com/product/H001/
HER2-ECD should be stored at - 80℃ (stable for at least 1 year). The buffer contains PBS without preservative. After thawing it should be stored in appropriate small aliquots at - 20℃ or - 80℃ (stable for at least 2 months).
Production platform:
HEK293 cells using the rPEx™ recombinant protein production platform.
データシートURL：
https://products.ipatherapeutics.com/product/H001/
| 保存温度 | -80°C | メーカー | ImmunoPrecise Antibodies (Europe) BV |
|---|---|---|---|
| 別称 | V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2, Receptor tyrosine-protein kinase erbB-2, Neuroblastoma/glioblastoma derived oncogene homolog, C-erb B2/neu protein, P185erbB2, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Metastatic lymph node gene 19 protein, Tyrosine kinase-type cell surface receptor HER2 | ||
| 背景 | Product description: Herstatin a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Herstatin has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported. Amplification and/or overexpression of this gene has been reported in numerous cancers, including gastric cancer, breast and ovarian tumors. Alternative splicing results in several additional transcript variants. \nResidues 22-646 of the most common allele, Ile654/Ile655, of human herstatin were cloned, the protein was over-expressed in HEK293EBNA1 cells and purified to homogeneity. The calculated molecular weight of recombinant human herstatin, residues 22-646, is 70.0 kDa. It contains an C-terminal hexahistidine tag. Reference sequences: Swiss-prot P04626 |
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※保存温度の表記について： RT: 室温
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