トップ > 製品検索結果一覧 > Code No. D198-3 Anti-CD93 (Human) mAb

Code No. D198-3

Anti-CD93 (Human) mAb

価格(税別)

¥42,000

在庫

10以上

(2022/08/10 17:30時点)

包装

100 µg/100 µL

データ
  • Immunoprecipitation

  • Flow Cytometry

  • Immunohistochemistry

クローナリティー Monoclonal クローン mNI-11
アイソタイプ
(免疫動物)
Mouse IgG1
使用法
IP
2 µg/400 µg of cell extract from 5x106 cells  
FCM
5 µg/mL (final concentration)  
IH
10 µg/mL (Can be used in cryosections.)  
Co-IP*
reported.  (PMID: 29763414
免疫原(抗原) LPS-stimulated U937
交差性
[Gene ID]

Human[22918]

性状 1 mg/mL in PBS/50% glycerol, pH 7.2
保存温度 -20°C 標識 Unlabeled メーカー MBL
別称 C1qRp
背景 CD93, also known as C1qRp, is a 100-125 kDa type I membrane protein that is a receptor for the complement protein C1q. CD93 has also been shown to act as a receptor for mannose-binding lectin and surfactant protein A. CD93 is expressed on the surface of monocytes, granulocytes, and endothelial cells, and expression is increased by TNF-α or GM-CSF. CD93 is involved in ligand-mediated enhancement of phagocytosis and intercellular adhesion.
関連製品 D198-5 Anti-CD93 (Human) mAb-PE
使用文献
使用文献募集中!本製品を使って論文を発表されましたら是非お知らせください。

Western Blotting

  1. Lugano R et al. CD93 promotes integrin-β1 activation and fibronectin fibrillogenesis during tumor angiogenesis. J Clin Invest. (2018) In press.(PMID:29763414)

Co-IP

  1. Lugano R et al. CD93 promotes integrin-β1 activation and fibronectin fibrillogenesis during tumor angiogenesis. J Clin Invest. (2018) In press.(PMID:29763414)

Flow Cytometry

  1. McGreal EP et al. Human C1qRp is identical with CD93 and the mNI-11 antigen but does not bind C1q. J Immunol. 15, 5222-32 (2002)(PMID:11994479)

Immunocytochemistry

  1. Lugano R et al. CD93 promotes integrin-β1 activation and fibronectin fibrillogenesis during tumor angiogenesis. J Clin Invest. (2018) In press.(PMID:29763414)
  2. Barbera S et al. The small GTPase Rab5c is a key regulator of trafficking of the CD93/Multimerin-2/β1 integrin complex in endothelial cell adhesion and migration. Cell Commun Signal. 17, 55 (2019)(PMID:31138217)
参考文献
  1. Ikewaki N, Inoko H. Development and characterization of a novel monoclonal antibody (mNI-11) that induces cell adhesion of the LPS-stimulated human monocyte-like cell line U937. J Leukoc Biol. 59, 697-708 (1996)(PMID: 8656055
  2. Ikewaki N et al. A unique monoclonal antibody mNI-11 rapidly enhances spread formation in human umbilical vein endothelial cells. J Clin immunol. 20, 317-24 (2000)(PMID: 10939719
  3. McGreal EP et al. Human C1qRp is identical with CD93 and the mNI-11 antigen but does not bind C1q. J Immunol. 168, 5222-32 (2002)(PMID: 11994479
  4. Ikewaki N et al. Regulation of CD93 cell surface expression by protein kinase C isoenzymes. Microbiol Immunol. 50, 93-103 (2006)(PMID: 16490927
  5. Ikewaki N et al. Decrease in CD93 (C1qRp) expression in a human monocyte-like cell line (U937) treated with various apoptosis-inducing chemical substances. Microbiol Immunol. 51, 1189-200 (2007)(PMID: 18094537
  6. Ikewaki N et al. Flow cytometric identification of CD93 expression on naive T lymphocytes (CD4(+)CD45RA (+) cells) in human neonatal umbilical cord blood. J Clin Immunol.30, 723-33 (2010)(PMID: 20512406
  7. Ikewaki N et al. Unique properties of cluster of differentiation 93 in the umbilical cord blood of neonates. Microbiol Immunol. 57, 822-32 (2013)(PMID: 24033555
  8. Ikewaki N et al. Serum levels of soluble CD93 in patients with chronic renal failure. J. of Kyushu Univ. of Health and Welfare 17, 81-8 (2016)
  9. Nativel B et al. CD93 is a cell surface lectin receptor involved in the control of the inflammatory response stimulated by exogenous DNA. Immunology. 158, 85-93 (2019)(PMID: 31335975
製品
カテゴリー
分野
細胞膜表面抗原
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※在庫につきましては2022年08月10日 17時30分時点における在庫数を表示してあります。
※価格の赤色表示につきましては、キャンペーン価格の表示となっております。
※このサイトからは直接注文はできません。ご注意ください。
※使用法の表記について:
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation,
FCM: Flow Cytometry NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation,
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
※使用法・交差性の表記について:
*: 論文で報告されております(MBLでは未確認)。詳しくはデータシートをご覧ください。
**: 導入元からの情報です(MBLでは評価中もしくは未確認)。
※保存温度の表記について: RT: 室温
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