トップ > 製品検索結果一覧 > Code No. CY-1160 CycLex® Rho-kinase Assay Kit

Code No. CY-1160

CycLex® Rho-kinase Assay Kit

価格(税別)

¥90,000

在庫

1-9

(2017/08/18 01:30時点)

包装

96 assays

データ

キット構成品 Microplate (coated with recombinant MBS C-terminus(758-1032 a.a.) as Rho-kinase substrate), 10×Wash Buffer, Kinase Buffer, 20×ATP, HRP conjugated Detection Antibody, Substrate Reagent, Stop Solution
使用目的 This Kit is primarily designed to measure the activities of purified Rho-kinase or DMPK for the rapid and sensitive evaluation of inhibitors or activators.
保存温度 4°C メーカー MBL
関連製品 CY-E1160-1 Rho-kinase II Positive Control
CY-E1160-2 DMPK Positive Control
CY-M1011 Anti-Phospho-MBS (MYPT1) (Thr696) mAb
使用文献 使用文献募集中!本製品を使って論文を発表されましたら是非お知らせください。
  1. Massaro M, Zampolli A, Scoditti E, Carluccio MA, Storelli C, Distante A, De Caterina R.; Statins inhibit cyclooxygenase-2 and matrix metalloproteinase-9 in human endothelial cells: anti-angiogenic actions possibly contributing to plaque stability. Cardiovasc Res, 86: 311-320, 2010(PMID:19946014)
  1. Yue Xu, Xiuwen Zhu, Heung Sik Hahm, Wanguo Wei, Ergeng Hao, Alberto Hayek, and Sheng Ding; Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small molecules. PNAS, 107: 8129-8134, 2010(PMID:20406903)
  1. Carlos Torre, Steven J. Wang, Weiliang Xia, and Lilly Y. W. Bourguignon; Reduction of Hyaluronan-CD44_Mediated Growth, Migration, and Cisplatin Resistance in Head and Neck Cancer Due to Inhibition of Rho Kinase and PI-3 Kinase Signaling. Arch Otolaryngol Head Neck Surg, 136: 493-501, 2010(PMID:20479382)
  1. Tamia K. Lapointe, Pamela M. O'Connor, Nicola L. Jones, Daniel Menard, Andre G. Buret; Interleukin-1 receptor phosphorylation activates Rho kinase to disrupt human gastric tight junctional claudin-4 during Helicobacter pylori infection. Cellular Microbiology 12: 692-703, 2010(PMID:20070312)
  1. Trinity J. Bivalacqua, Ashley E. Ross, Travis D. Strong, Milena A. Gebska, Biljana Musicki, Hunter C. Champion and Arthur L. Burnett; Attenuated RhoA/Rho-kinase Signaling in Penis of Transgenic Sickle Cell Mice. Urology 76: 510.e7-510.e12, 2010(PMID:20538321)
  1. Sijin Liu, Shitao Li, Yuguo Du; Polychlorinated Biphenyls (PCBs) Enhance Metastatic Properties of Breast Cancer Cells by Activating Rho-Associated Kinase (ROCK). PLoS ONE 5: e11272, 2010(PMID:20585605)
  1. Cyrill G_raud, Kai Schledzewski, Alexandra Demory, Diana Klein, Miriam Kaus, Francis Peyre, Carsten Sticht, Konstantin Evdokimov, Shun Lu, Astrid Schmieder, Sergij Goerdt; Liver sinusoidal endothelium: A microenvironment-dependent differentiation program in rat including the novel junctional protein liver endothelial differentiation-associated protein-1. Hepatology 52: 313-326, 2010(PMID:20578158)
  1. Masatake Fujimura, Fusako Usuki, Miwako Kawamura and Shuji Izumo; Inhibition of the Rho/ROCK pathway prevents neuronal degeneration in vitro and in vivo following methylmercury exposure. Toxicology and Applied Pharmacology 250: 1-9, 2011(PMID:20869980)
  1. S. Duong-Quy, P. Dao, T. Hua-Huy, C. Guilluy, P. Pacaud and A.T. Dinh-Xuan; Increased Rho-kinases expression and activity and pulmonary endothelial dysfunction in smokers with normal lung function. Eur Respir J, 37: 349-55, 2011(PMID:20530044)
  1. Y. Smitasiri, P. D’Souza, J. Neal-Kababick and A.G. Schauss; An Initial Evaluation of the Safety, Efficacy and Purity of VigRX, a Herbal Combination Formula, for the Enhancement of Male Sexual Health. The Open Natural Products Journal, 3: 10-19, 2010
  1. Xiaoxiao Gu1 and Kristyn S Masters; Role of the Rho pathway in regulating valvular interstitial cell phenotype and nodule formation. AJP Heart and Circulatory Physiology, 300: H448-58, 2011(PMID:21131478)
  1. Duong-Quy S, Dao P, Hua-Huy T, Guilluy C, Pacaud P, Dinh-Xuan AT.; Increased Rho-kinase expression and activity and pulmonary endothelial dysfunction in smokers with normal lung function. Eur Respir J, 37: 349-55, 2011(PMID:20530044)
  1. Kirabo A, Kearns PN, Jarajapu YP, Sasser JM, Oh SP, Grant MB, Kasahara H, Cardounel AJ, Baylis C, Wagner KU, Sayeski PP.; Vascular smooth muscle Jak2 mediates angiotensin II-induced hypertension via increased levels of reactive oxygen species. Cardiovasc Res, 91: 171-9, 2011(PMID:21354995)
  1. Xiaoxiao Gu and Kristyn S. Masters; Role of the Rho pathway in regulating valvular interstitial cell phenotype and nodule formation. Am J Physiol Heart Circ Physiol, 300: H448 - H458, 2011(PMID:21131478)
  1. Riganti C, Pinto H, Bolli E, Belisario DC, Calogero RA, Bosia A, Cavallo F.; Atorvastatin modulates anti-proliferative and pro-proliferative signals in Her2/neu-positive mammary cancer. Biochem Pharmacol. 82: 1079-89, 2011(PMID:21803026)
  1. Haidari M, Zhang W, Ganjehei L, Ali M, Chen Z.; Inhibition of MLC phosphorylation restricts replication of influenza virus--a mechanism of action for anti-influenza agents. PLoS One. 6(6):e21444.2011(PMID:21731751)
  1. N_lle A, Zeug A, van Bergeijk J, T_nges L, Gerhard R, Brinkmann H, Al Rayes S, Hensel N, Schill Y, Apkhazava D, Jablonka S, Omer J, Srivastav RK, Baasner A, Lingor P, Wirth B, Ponimaskin E, Niedenthal R, Grothe C, Claus P.; The Spinal Muscular Atrophy disease protein SMN is linked to the Rho-kinase pathway via profilin. Hum Mol Genet. 20: 4865-78. 2011(PMID:21920940)
  1. Fujimura M, Usuki F, Kawamura M, Izumo S.; Inhibition of the Rho/ROCK pathway prevents neuronal degeneration in vitro and in vivo following methylmercury exposure. Toxicol Appl Pharmacol. 250: 1-9. 2011(PMID:20869980)
  1. Bagi Z, Feher A, Cassuto J, Akula K, Labinskyy N, Kaley G, Koller A.; Increased availability of angiotensin AT 1 receptors leads to sustained arterial constriction to angiotensin II in diabetes - role for Rho-kinase activation. Br J Pharmacol. 163: 1059-68. 2011(PMID:21385178)
  1. Hiroyuki Kobori, Yuri Ozawa, Omar W Acres, Kayoko Miyata, and Ryousuke Satou; Rho-kinase/nuclear factor-κβ/angiotensinogen axis in angiotensin II-induced renal injury. Hypertens Res. 34: 976_979. 2011(PMID:21633359)
  1. Shahin R, Alqtaishat S, Taha MO.; Elaborate ligand-based modeling reveal new submicromolar Rho kinase inhibitors. J Comput Aided Mol Des. 26: 249-66. 2012(PMID:22167443)
  1. Morckel AR, Lusic H, Farzana L, Yoder JA, Deiters A, Nascone-Yoder NM.; A photoactivatable small-molecule inhibitor for light-controlled spatiotemporal regulation of Rho kinase in live embryos. Development. 139: 437-42. 2012(PMID:22186732)
  1. Trevor Luke, Julie Maylor, Clark Undem, J. T. Sylvester, and Larissa A. Shimoda; Kinase dependent activation of voltage-gated Ca2+ channels by ET-1 in pulmonary arterial myocytes during chronic hypoxia. Am J Physiol Lung Cell Mol Physiol. 302: L1128-39. 2012(PMID:22387294)
  1. Tzu-Ching Chang, Yen-Chung Chen, Ming-Hua Yang, Chien-Hung Chen, En-Wei Hsing, Bor-Sheng Ko, Jun-Yang Liou,1 and Kenneth K. Wu1; Rho Kinases Regulate the Renewal and Neural Differentiation of Embryonic Stem Cells in a Cell Plating Density_Dependent Manner. PLoS One, 5: e9187, 2010(PMID:20169147)
  1. Naraoka M et al. Suppression of the Rho/Rho-kinase pathway and prevention of cerebral vasospasm by combination treatment with statin and fasudil after subarachnoid hemorrhage in rabbit. Transl Stroke Res. 4, 368-74 (2013)(PMID:23658597)
  1. Dush MK and Nascone-Yoder NM. Jun N-terminal kinase maintains tissue integrity during cell rearrangement in the gut. Development. 140, 1457-66 (2013)(PMID:23462475)
  1. Liang JL et al. Effects of interleukin-1β on vascular reactivity after lipopolysaccharide-induced endotoxic shock in rabbits and its relationship with PKC and Rho kinase. J Cardiovasc Pharmacol. 62, 84-9 (2013)(PMID:23846803)
  1. Riganti C et al. Zoledronic acid restores doxorubicin chemosensitivity and immunogenic cell death in multidrug-resistant human cancer cells. PLoS One. 8, e60975 (2013)(PMID:23593363)
  1. Takata M et al. Fasudil, a rho kinase inhibitor, limits motor neuron loss in experimental models of amyotrophic lateral sclerosis. Br J Pharmacol. 170, 341-51 (2013)(PMID:23763343)
  1. Bourguignon LY et al. Selective matrix (hyaluronan) interaction with CD44 and RhoGTPase signaling promotes keratinocyte functions and overcomes age-related epidermal dysfunction. J Dermatol Sci. 72, 32-44 (2013)(PMID:23790635)
  1. Bei Y et al. Activation of RhoA/Rho-kinase pathway accounts for pulmonary endothelial dysfunction in patients with chronic obstructive pulmonary disease. Physiol Rep. 1, e00105 (2013)(PMID:24303177)
  1. Sari AN et al. Contribution of RhoA/Rho-kinase/MEK1/ERK1/2/iNOS pathway to ischemia/reperfusion-induced oxidative/nitrosative stress and inflammation leading to distant and target organ injury in rats. Eur J Pharmacol. 723, 234-45 (2014)(PMID:24296316)
  1. Kheirollah A et al. Involvement of cdc42/Rho kinase in apoA-I-mediated cholesterol efflux through interaction between cytosolic lipid-protein particles and microtubules in rat astrocytes. J Neurosci Res. 92, 455-63 (2014)(PMID:24446142)
  1. Li YH et al. Intranasal delivery of FSD-C10, a novel Rho kinase inhibitor, exhibits therapeutic potential in experimental autoimmune encephalomyelitis. Immunology. 143, 219-29 (2014)(PMID:24749492)
  1. Liu D et al. The glucocorticoid dexamethasone inhibits U937 cell adhesion and neutrophil release via RhoA/ROCK1-dependent and independent pathways. Cell Physiol Biochem. 33, 1654-62 (2014)(PMID:24902944)
  1. Pinzón-Daza ML et al. The cross-talk between canonical and non-canonical Wnt-dependent pathways regulates P-glycoprotein expression in human blood-brain barrier cells. J Cereb Blood Flow Metab. 34, 1258-69 (2014)(PMID:24896565)
  1. Chen Z et al. cIMP synthesized by sGC as a mediator of hypoxic contraction of coronary arteries. Am J Physiol Heart Circ Physiol. 307, H328-36 (2014)(PMID:24906916)
  1. Kwok W and Clemens MG. Rho-kinase activation contributes to Lps-induced impairment of endothelial nitric oxide synthase activation by endothelin-1 in cultured hepatic sinusoidal endothelial cells. Shock. 42, 554-61 (2014)(PMID:25243430)
  1. Li H et al. Design, synthesis and evaluation of biological activity of novel fasudil analogues. Pharmazie. 69, 867-73 (2014)(PMID:25951658)
製品
カテゴリー
分野
ドラッグディスカバリー
シグナル伝達
この製品に関するお問い合わせをする

※在庫につきましては2017年08月18日 01時30分時点における在庫数を表示してあります。
※価格の赤色表示につきましては、キャンペーン価格の表示となっております。
※このサイトからは直接注文はできません。ご注意ください。
※保存温度の表記について: RT: 室温
※本サイトの掲載製品は、品質改良のため予告なく仕様などの変更、または販売中止となる場合がございます。あらかじめご了承ください。