トップ > 製品検索結果一覧 > Code No. PD010 Anti-ATBF1 (D1-120) pAb

Code No. PD010

Anti-ATBF1 (D1-120) pAb

価格(税別)

¥52,800

在庫

10以上

(2024/04/26 17:00時点)

包装

100 µL

データ
  • Western Blotting

  • Immunoprecipitation

  • Immunocytochemistry

  • Immunohistochemistry

  • Immunohistochemistry

クローナリティー Polyclonal クローン Polyclonal
アイソタイプ
(免疫動物)
Rabbit IgG
使用法
WB
1:2,000  
IP
1 µL/150 µg of cell lysate  
IC
1:500  
IH
1:2,500-1:5,000  
IF
1:500  
免疫原(抗原) recombinant region of human ATBF1 (2107-2147 aa.) corresponding to the identical amino acid sequence of mouse ATBF1 (2114-2154 aa.)
交差性
[Gene ID]

Human[463], Mouse[11906], Rat[307829]

性状 PBS/50% glycerol, pH 7.2
保存温度 -20°C 標識 Unlabeled メーカー MBL
別称 ZFHX3, ATBT, ZNF927
背景 ATBF1 (also known as ZFHX3) is a transcription factor that has two-protein isoforms, the 404 kDa ATBF1-A and the 306 kDa ATBF1-B. ATBF1-A contains four homeodomains and 23 zinc-finger motifs.
ATBF1-B contains four homeodomains and 18 zinc fingers. ATBF1 is identified as DNA-binding protein, which binds to an AT-rich element of the human α-fetoprotein (AFP) gene, as a result suppressing its transcription activity. ATBF1 is also involved in cell cycle arrest and cooperating with p53 to activate the p21Waf1/Cip1 promoter. ATBF1 is expressed in the differentiation fields in association with β-tubulin III and MAP2 that are the neuronal differentiation marker. ATBF1 plays a crucial role in neuronal development and cell cycle arrest.
関連製品 PD011 Anti-ATBF1 (AT-6) pAb
使用文献
使用文献募集中!本製品を使って論文を発表されましたら是非お知らせください。

Western Blotting

  1. Zhang S et al. AT motif binding factor 1 (ATBF1) is highly phosphorylated in embryonic brain and protected from cleavage by calpain-1. Biochem Biophys Res Commun. 427, 537-41 (2012)(PMID:23022192)
  2. Chen XH et al. Mebendazole elicits potent antimyeloma activity by inhibiting the USP5/c-Maf axis. Acta Pharmacol Sin. 40, 1568-1577 (2019)(PMID:31152485)
  3. Zhang Z et al. Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons. Exp Neurol. 322, 113055 (2019)(PMID:31491374)

Immunocytochemistry

  1. Kawaguchi M et al. A diagnostic marker for superficial urothelial bladder carcinoma: lack of nuclear ATBF1 (ZFHX3) by immunohistochemistry suggests malignant progression. BMC Cancer 16, 805 (2016)(PMID:27756245)

Immunohistochemistry

  1. Kim TS et al. The ZFHX3 (ATBF1) transcription factor induces PDGFRB, which activates ATM in the cytoplasm to protect cerebellar neurons from oxidative stress. Dis Model Mech. 3, 752-62 (2010)(PMID:20876357)
  2. Uhm KO et al. ATBF1 is a novel amyloid-β protein precursor (AβPP) binding protein that affects AβPP expression. J Alzheimers Dis. 43, 243-57 (2015)(PMID:25079792)
  3. Zhang Z et al. Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons. Exp Neurol. 322, 113055 (2019)(PMID:31491374)
  4. Dong G et al. ZFHX3 Promotes the Proliferation and Tumor Growth of ER-Positive Breast Cancer Cells Likely by Enhancing Stem-Like Features and MYC and TBX3 Transcription. Cancers (Basel). 12, 3415 (2020)(PMID:33217982)

Immunofluorescence

  1. Jung CG et al. Homeotic factor ATBF1 induces the cell cycle arrest associated with neuronal differentiation. Development 132, 5137-45 (2005)(PMID:16251211)
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※在庫につきましては2024年04月26日 17時00分時点における在庫数を表示してあります。
※価格の赤色表示につきましては、キャンペーン価格の表示となっております。
※このサイトからは直接注文はできません。ご注意ください。
※使用法の表記について:
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation,
FCM: Flow Cytometry NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation,
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
※使用法・交差性の表記について:
*: 論文で報告されております(MBLでは未確認)。詳しくはデータシートをご覧ください。
**: 導入元からの情報です(MBLでは評価中もしくは未確認)。
※保存温度の表記について: RT: 室温
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