This site is for customers in Japan. Customers in other regions, please go to Global page.
HOME > Product search results > Code No. 4800-520 Caspase inhibitor Z-VAD-FMK

Code No. 4800-520

Caspase inhibitor Z-VAD-FMK

Price

¥40,000

Availability (in Japan)

10 or more

(In Japan at 00:05,
Oct 24, 2019 in JST)

Size

20 µL

Storage temp. -20°C Manufacturer MBL
Related products 4800-510 Caspase-3 inhibitor Z-DEVD-FMK
4805-510 Caspase-8 inhibitor Z-IETD-FMK
4810-510 Caspase-9 inhibitor Z-LEHD-FMK
4800 APOPCYTO™ Caspase-3 Colorimetric Assay Kit
4815 APOPCYTO™ Caspase-3 Fluorometric Assay Kit
4805 APOPCYTO™ Caspase-8 Colorimetric Assay Kit
4820 APOPCYTO™ Caspase-8 Fluorometric Assay Kit
4810 APOPCYTO™ Caspase-9 Colorimetric Assay Kit
4825 APOPCYTO™ Caspase-9 Fluorometric Assay Kit
Citations
  1. Ito T et al. Antitumor effect of resveratrol oligomers against human cancer cell lines and the molecular mechanism of apoptosis induced by vaticanol C. Carcinogenesis. 24, 1489-97 (2003)(PMID:12844481)
  1. Kobayashi S et al. 53BP2 induces apoptosis through the mitochondrial death pathway. Genes Cells. 10, 253-60 (2005)(PMID:15743414)
  1. Matsumoto T et al. Antiproliferative and apoptotic effects of butyrolactone lignans from Arctium lappa on leukemic cells. Planta Med. 72, 276-8 (2006)(PMID:16534737)
  1. Nakagawa Y et al. Characterized mechanism of alpha-mangostin-induced cell death: caspase-independent apoptosis with release of endonuclease-G from mitochondria and increased miR-143 expression in human colorectal cancer DLD-1 cells. Bioorg Med Chem. 15, 5620-8 (2007)(PMID:17553685)
  1. Yuan G et al. The distribution and ultrastructure of the forming blood capillaries and the effect of apoptosis on vascularization in mouse embryonic molar mesenchyme. Cel Tissue Res. 356, 137-45 (2014)(PMID:24477797)
  1. Kozako T et al. Novel small-molecule SIRT1 inhibitors induce cell death in adult T-cell leukaemia cells. Sci Rep. 5, 11345 (2015)(PMID:26091232)
  1. Sagiv A et al. Granule exocytosis mediates immune surveillance of senescent cells. Oncogene 32, 1971–1977 (2013)(PMID:26935269)
  1. Wang C et al. A bead-based cleavage method for large-scale identification of protease substrates. Sci Rep. 6, 22645 (2016)(PMID:26935269)
  1. Kitazawa M et al. ASC Induces Apoptosis via Activation of Caspase-9 by Enhancing Gap Junction-Mediated Intercellular Communication. PLoS One. 12, e0169340 (2017)(PMID:28056049)
  1. Tokunaga E et al. Biological evaluation of both enantiomers of fluoro-thalidomide using human myeloma cell line H929 and others. PLoS One. 12, e0182152 (2017)(PMID:28763493)
  1. Hsu JM et al. STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion. Nat Commun. 9, 1908 (2018)(PMID:29765039)
  1. Kozako T et al. The small molecule STF-62247 induces apoptotic and autophagic cell death in leukemic cells. Oncotarget 9, 27645-27655 (2018)(PMID:29963226)
  1. Kozako T et al. Novel small molecule SIRT2 inhibitors induce cell death in leukemic cell lines. BMC Cancer. 18, 791 (2018)(PMID:30081901)
  1. Hirasawa M, Kurita-Ochiai T. Porphyromonas gingivalis Induces Apoptosis and Autophagy via ER Stress in Human Umbilical Vein Endothelial Cells. Mediators Inflamm. 2018, 1967506 (2018)(PMID:30150893)
  1. Zhang E et al. The functional role of Bax/Bak in palmitate-induced lipoapoptosis. Food Chem Toxicol. 123, 268-274 (2019)(PMID:30408539)

Function

  1. Hoshi T et al. Lenvatinib induces death of human hepatocellular carcinoma cells harboring an activated FGF signaling pathway through inhibition of FGFR-MAPK cascades. Biochem Biophys Res Commun. 513, 1-7 (2019)(PMID:30944079)
References
  1. Slee EA et al. Benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone (Z-VAD.FMK) inhibits apoptosis by blocking the processing of CPP32. Biochem J. 315, 21-24 (1996)(PMID: 8670109
Product category
Research area
Apoptosis
この製品に関するお問い合わせをする

  • The availability is based on the information in Japan at 00:05, Oct 24, 2019 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.