Anti-IGFBP1 (Human) mAb

Price

¥52,800

Availability (in Japan)

10 or more

（In Japan at 00:05,
Jan 24, 2025 in JST）

Size

100 µL (1 mg/mL)

Data Sheet

SDS

Data	Flow Cytometry
Clonality	Monoclonal	Clone	2B9-2
Isotype (Immunized Animal)	Mouse IgG2bκ
Applications	FCM 1-10 µg/mL
Immunogen (Antigen)	Human IGFBP1 expressed Ba/F3transfectants generated from SST-REX (signal sequence trap by retrovirus-mediated expression screening).
Reactivity [Gene ID]	Human[3438]
Storage buffer	PBS/50% glycerol, pH 7.2
Storage temp.	-20°C	Conjugate	Unlabeled	Manufacturer	MBL
Alternative names	AFBP, IBP1, PP12, IGF-BP25, hIGFBP-1
Background	IGFBP1, also known as placental protein 12 (PP12), is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin domain. IGFBP1 circulates in the plasma and has been shown to either inhibit or stimulate the growth promoting effects of its ligands called insulin-like growth factors (IGFs) I and II. High expression levels of IGFBP1 have been implicated in metastasis of prostate cancer.
Related products	M076-3 Mouse IgG2a (isotype control) MTG-001 Clear Back (Human Fc receptor blocking reagent) W164-3 Anti-RHBDD3 (Human) mAb
References	Kojima T, Kitamura T. A signal sequence trap based on a constitutively active cytokine receptor. Nat Biotechnol. 17, 487-90 (1999)（PMID: 10331810） Dolcini L et al. Identification of the amniotic fluid insulin-like growth factor binding protein-1 phosphorylation sites and propensity to proteolysis of the isoforms. . 276, 6033-46 (2009)（PMID: 197650） Sala A et al. Structure and properties of the C-terminal domain of insulin-like growth factor-binding protein-1 isolated from human amniotic fluid. J Biol Chem. 280, 29812-9 (2005)（PMID: 15972819） Jones JI et al. Identification of the sites of phosphorylation in insulin-like growth factor binding protein-1. Regulation of its affinity by phosphorylation of serine 101. J Biol Chem. 268, 1125-31 (1993)（PMID: 7678248）
Product category	Research area Cancer Tools Flow cytometry reagents

The availability is based on the information in Japan at 00:05, Jan 24, 2025 in JST.
The special price is shown in red color.
Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
For storage temparature: RT: room temparature
Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.