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HOME > Product search results > Code No. D128-3 Anti-Phospho-STAT3 (Tyr708) mAb

Code No. D128-3

Anti-Phospho-STAT3 (Tyr708) mAb

Price

¥48,000

Availability (in Japan)

10 or more

(In Japan at 17:00,
May 29, 2020 in JST)

Size

100 µg/100 µL

This antibody reacts with human and mouse STAT3 phosphorylated at Tyr705, and zebrafish STAT3 phosphorylated at Tyr708.
Data
  • Western Blotting

Clonality Monoclonal Clone PS3/1
Isotype (Immunized Animal) Mouse IgG1
Applications
WB
1 μg/mL  
Immunogen (Antigen) 12 peptide including phospho-Tyr708 of Zebrafish STAT3 (CVTQPpYLKTKFI) (703-714 a.a.)
Reactivity [Gene ID]

Human[6774], Mouse[20848]

Storage buffer PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names APRF, HIES
Background STAT (Signal Transducers and Activators of Transcription) proteins play important roles in development, cell differentiation and cell cycle control.  STAT3 is an ~85 kDa protein involved in the signaling pathways of many cytokines and growth factors, including G-CSF and IL-6, where it functions as a negative regulator of transcription. STAT3 is also constitutively activated in a number of human tumors and it possesses anti-apoptotic activity and oncogenic potential. STAT3 may also regulate apoptosis by inhibiting NF-κB. Activation of STAT3 by tyrosine phosphorylation results in dimerization, nuclear translocation and DNA binding.
Product category
Cancer
Research area
Cancer
Signal transduction
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  • The availability is based on the information in Japan at 17:00, May 29, 2020 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.