Price
¥52,800
Availability (in Japan)
10 or more
(In Japan at 00:05,
Jun 30, 2024 in JST)
Size
100 µL (1 mg/mL)
Data | |||||
---|---|---|---|---|---|
Clonality | Monoclonal | Clone | PS3/1 | ||
Isotype (Immunized Animal) | Mouse IgG1 | ||||
Applications | |||||
Immunogen (Antigen) | 12 peptide including phospho-Tyr708 of Zebrafish STAT3 (CVTQPpYLKTKFI) (703-714 a.a.) | ||||
Reactivity [Gene ID] | |||||
Storage buffer | PBS/50% glycerol, pH 7.2 | ||||
Storage temp. | -20°C | Conjugate | Unlabeled | Manufacturer | MBL |
Alternative names | APRF, HIES | ||||
Background | STAT (Signal Transducers and Activators of Transcription) proteins play important roles in development, cell differentiation and cell cycle control. STAT3 is an ~85 kDa protein involved in the signaling pathways of many cytokines and growth factors, including G-CSF and IL-6, where it functions as a negative regulator of transcription. STAT3 is also constitutively activated in a number of human tumors and it possesses anti-apoptotic activity and oncogenic potential. STAT3 may also regulate apoptosis by inhibiting NF-κB. Activation of STAT3 by tyrosine phosphorylation results in dimerization, nuclear translocation and DNA binding. | ||||
Citations |
Western Blotting
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Product category |
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