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HOME > Product search results > Code No. D073-3 Anti-Synaptophysin mAb

Code No. D073-3

Anti-Synaptophysin mAb

Price

¥48,000

Availability (in Japan)

1-9

(In Japan at 17:00,
Nov 22, 2019 in JST)

Size

100 µg/100 µL

Data
  • Western Blotting

Clonality Monoclonal Clone 171B5
Isotype (Immunized Animal) Mouse IgG1
Applications
WB
1 µg/mL  
IC*
reported.  (PMID: 19222710
IH
10 µg/mL  
Immunogen (Antigen) purified synaptic vesicle fraction from guinea pig cerebrum
Reactivity [Gene ID]

Human[6855], Mouse[20977], Rat*[24808](PMID: 19222710/20609425)

Storage buffer 1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names SYP, MRXSYP
Background Synaptophysin (also named as SVP38 and p38) is an acidic Ca2+ binding glycoprotein of about 38 kDa which exist largely in synaptic vesicles. It has 4 transmembrane regions and reported that it is a major cholesterol-binding protein in synaptic vesicles. Synaptophysin may regulate synaptic exocytosis by competing with proteins such as SNAP25 and syntaxins for binding synaptobrevin (vesicle-associated membrane protein, or VAMP). It may also participate in synaptic endocytosis, which contributes to rapid recycling of synaptic vesicle.
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Citations

Western Blotting

  1. Kojima N et al. Genetic disruption of the alternative splicing of drebrin gene impairs context-dependent fear learning in adulthood. Neuroscience. 165, 138-150 (2010)(PMID:19837137)
  2. Liu Y et al. Disturbances of soluble N-ethylmaleimide-sensitive factor attachment proteins in hippocampal synaptosomes contribute to cognitive impairment after repetitive formaldehyde inhalation in male rats. Neuroscience. 169, 1248-1254 (2010)(PMID:20609425)

Immunocytochemistry

  1. Mizui T et al. Drebrin E is involved in the regulation of axonal growth through actin-myosin interactions. J Neurochem. 109, 611-622 (2009)(PMID:19222710)
Product category
Research area
Neuroscience
この製品に関するお問い合わせをする

  • The availability is based on the information in Japan at 17:00, Nov 22, 2019 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.