Price
¥48,000
Availability (in Japan)
10 or more
(In Japan at 00:05,
Jul 1, 2022 in JST)
Size
100 µg/100 µL
Data | |||||
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Clonality | Monoclonal | Clone | 171B5 | ||
Isotype (Immunized Animal) | Mouse IgG1 | ||||
Applications |
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Immunogen (Antigen) | purified synaptic vesicle fraction from guinea pig cerebrum | ||||
Reactivity [Gene ID] | Human[6855], Mouse[20977], Rat*[24808](PMID: 19222710/20609425) |
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Storage buffer | 1 mg/mL in PBS/50% glycerol, pH 7.2 | ||||
Storage temp. | -20°C | Conjugate | Unlabeled | Manufacturer | MBL |
Alternative names | SYP, MRXSYP | ||||
Background | Synaptophysin (also named as SVP38 and p38) is an acidic Ca2+ binding glycoprotein of about 38 kDa which exist largely in synaptic vesicles. It has 4 transmembrane regions and reported that it is a major cholesterol-binding protein in synaptic vesicles. Synaptophysin may regulate synaptic exocytosis by competing with proteins such as SNAP25 and syntaxins for binding synaptobrevin (vesicle-associated membrane protein, or VAMP). It may also participate in synaptic endocytosis, which contributes to rapid recycling of synaptic vesicle. | ||||
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Citations |
Western Blotting
Immunocytochemistry
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Product category |
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