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HOME > Product search results > Code No. D351-3 Anti-Reelin (Mouse) mAb

Code No. D351-3

Anti-Reelin (Mouse) mAb



Availability (in Japan)

10 or more

(In Japan at 17:00,
Jul 3, 2020 in JST)


100 µg/100 µL

  • Western Blotting

Clonality Monoclonal Clone 2F3
Isotype (Immunized Animal) Mouse IgG1 κ
1 µg/mL  
reported.  (PMID: 24644294
Immunogen (Antigen) KLH conjugated synthetic peptide, YEKPAFDYC (corresponding to amino acid residues 1241-1248 of mouse Reelin).
Reactivity [Gene ID]


Storage buffer 1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names Reln, reelin, rl, reeler
Background Reelinは、388 kDaからなる細胞外マトリックスの糖タンパク質であり、セリンプロテアーゼ活性を持つ。ReelinはApoER2/VLDLRの2つのReelin受容体と結合したのち,細胞内タンパク質であるDab1をリン酸化する。

Reelinの構造は、シグナル配列、SP配列に続いてReelin特異的なH配列が存在し、その後ろに300~350残基のアミノ酸配列が8回繰り返されるReelin repeatsで構成されている。リピート2と3の間のN-t cleavage、およびリピート6と7の間のC-t cleavageによって切断を受ける。本モノクローナル抗体は、R2切断部位をまたぐペプチドを免疫し、N-t cleavageを受けたReelinを認識しない抗体である。N-t cleavageによりReelinは不活性化されるため、本モノクローナル抗体は、活性型Reelinを特異的に認識するモノクローナル抗体である。


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Western Blotting

  1. Koie M et al. Cleavage within Reelin repeat 3 regulates the duration and range of the signaling activity of Reelin protein. J Biol Chem. 289, 12922-30 (2015)(PMID:24644294)


  1. Koie M et al. Cleavage within Reelin repeat 3 regulates the duration and range of the signaling activity of Reelin protein. J Biol Chem. 289, 12922-30 (2015)(PMID:24644294)
Product category
Research area

  • The availability is based on the information in Japan at 17:00, Jul 3, 2020 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.