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HOME > Product search results > Code No. CY-P1041 Anti-c-IAP1 & 2 pAb

Code No. CY-P1041

Anti-c-IAP1 & 2 pAb

Price

¥40,000

Availability (in Japan)

1-9

(In Japan at 17:00,
Aug 6, 2020 in JST)

Size

100 µg

Data
  • Western Blotting

    WB analysis of endogenous human c-IAP 1&2 proteins

    WB analysis of endogenous human c-IAP 1&2 proteins

Clonality Polyclonal Clone Polyclonal
Isotype (Immunized Animal) Rabbit IgG
Applications
WB
0.5-2 µg/mL  
Immunogen (Antigen) Recombinant Ratfull length c-IAP1
Reactivity [Gene ID]

Human, Mouse, Rat

Storage buffer 1.0 mg/mL in 20 mM PBS/300 mM NaCl/50 % glycerol, pH 7.5
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Citations
  1. Marivin A et al. cIAP1 regulates TNF-mediated cdc42 activation and filopodia formation. Oncogene. 33, 5534-45 (2014)(PMID:24276241)

Western Blotting

  1. Shutinoski B et al. K45A mutation of RIPK1 results in poor necroptosis and cytokine signaling in macrophages, which impacts inflammatory responses in vivo. Cell Death Differ. 23, 1628-37 (2016)(PMID:27258786)
  2. Dobson CC et al. Oncolytic virus synergizes with Smac mimetic compounds to induce rhabdomyosarcoma cell death in a syngeneic murine model. Oncotarget 8, 3495-3508 (2017)(PMID:27966453)
  3. Patel R et al. Culling of APCs by inflammatory cell death pathways restricts TIM3 and PD-1 expression and promotes the survival of primed CD8 T cells. Cell Death Differ. 24, 1900-1911 (2017)(PMID:28686578)
  4. Kim DS et al. Smac mimetics and oncolytic viruses synergize in driving anticancer T-cell responses through complementary mechanisms. Nat Commun. 8, 344 (2017)(PMID:28839138)
  5. Alturki NA et al. cIAP1 regulates TNF-mediated cdc42 activation and filopodia formation. Cell Death Dis. 9, 592 (2018)(PMID:29789521)
  6. Beug ST et al. The transcription factor SP3 drives TNF-α expression in response to Smac mimetics. Sci Signal. 12, pii: eaat9563 (2019) (PMID:30696705)
  7. Lala-Tabbert N et al. Targeted ablation of the cellular inhibitor of apoptosis 1 (cIAP1) attenuates denervation-induced skeletal muscle atrophy. Skelet Muscle. 9, 13 (2019)(PMID:31126323)
  8. Tanmay M Shekha et al. Smac Mimetics LCL161 and GDC-0152 Inhibit Osteosarcoma Growth and Metastasis in Mice . BMC Cancer.19, 924(2019)(PMID:31521127)
Product category
Research area
Apoptosis
この製品に関するお問い合わせをする

  • The availability is based on the information in Japan at 17:00, Aug 6, 2020 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.