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HOME > Product search results > Code No. RN118PW Anti-UPF3B pAb

Code No. RN118PW

Anti-UPF3B pAb

Availability (in Japan)

10 or more

(In Japan at 01:30,
Sep 21, 2017 in JST)

Size

100 µg/100 µL

Data
  • Western Blotting

  • Immunoprecipitation

Clonality Polyclonal Clone Polyclonal
Isotype (Immunized Animal) Rabbit Ig (aff.)
Applications
WB
1:1,000  
IP
5 μL/500 μL of cell extract from 1 x 107 cells  
Reactivity [Gene ID]

Human[65109], Mouse[68134], Rat[313449], Hamster[100767364]

Storage buffer 1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names MRX62, UPF3X, HUPF3B, MRXS14, RENT3B
Background mRNA surveillance is the quality control mechanism to detect and eliminate abnormal mRNAs in eukaryotes. Nonsense-mediated mRNA decay (NMD) is one of the mRNA surveillance systems under which mRNAs containing pre-termination codons (PTCs) are selectively degraded. UPF3B, a core component of NMD machinery, is involved in various processes such as mRNA nuclear export, NMD and mRNA translation. In nucleus, UPF3B associates with exon junction complex (EJC) on mRNA and travels to cytoplasm. In cytoplasm, UPF3B bound EJC on mRNA interacts with its homologues UPF1 and UPF2, and promotes NMD by enhancing ATP-dependent helicase activity of UPF1 together with UPF2.
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Product category
Research area
RNA-RNP Network
Epigenetics
Neuroscience
Brands
RiboCluster Profiler™
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  • The availability is based on the information in Japan at 01:30, Sep 21, 2017 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.