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HOME > Product search results > Code No. MK-12-3 Anti-Ubiquitin mAb

Code No. MK-12-3

Anti-Ubiquitin mAb

Availability (in Japan)

10 or more

(In Japan at 00:05,
Jul 19, 2018 in JST)

Size

100 µg/100 µL

This antibody (clone 2C5) does not react with multi ubiquitin.
Data
  • Western Blotting

Clonality Monoclonal Clone 2C5
Isotype (Immunized Animal) Mouse IgG1
Applications
WB
5 µg/mL  
IP*
reported.  (PMID: 10488153
IC*
reported.  (PMID: 10906068
Immunogen (Antigen) Bovine erythrocyte ubiquitin
Reactivity [Gene ID]

Human, Mouse, Rat, Bovine

Storage buffer PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Background Ubiquitin is a polypeptide of 76 amino acid residues, and widely distributed protein in eukaryotic cells. This protein is also highly conserved among eukaryotic cells. There are several reports showed that intracellular abnormal and short-lived proteins are degraded through an ubiquitin dependent proteolytic pathway. In the ubiquitin dependent pathway, a target protein is tagged with multi-ubiquitin molecules.
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Citations

Western Blotting

  1. Sutovsky P et al. Ubiquitinated sperm mitochondria, selective proteolysis, and the regulation of mitochondrial inheritance in mammalian embryos. Biol Reprod. 63, 582-90 (2000)(PMID:10906068)
  2. Ott DE et al. Retroviruses have differing requirements for proteasome function in the budding process. J Virol. 77, 3384-93 (2003)(PMID:12610113)

Immunoprecipitation

  1. Hiyama H et al. Interaction of hHR23 with S5a. The ubiquitin-like domain of hHR23 mediates interaction with S5a subunit of 26 S proteasome. J Biol Chem. 274, 28019-25 (1999)(PMID:10488153)

Immunocytochemistry

  1. Sutovsky P et al. Ubiquitinated sperm mitochondria, selective proteolysis, and the regulation of mitochondrial inheritance in mammalian embryos. Biol Reprod. 63, 582-90 (2000)(PMID:10906068)
Product category
Research area
Ubiquitin proteasome
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  • The availability is based on the information in Japan at 00:05, Jul 19, 2018 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.