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HOME > Product search results > Code No. D092-6 Anti-CD274 (PD-L1) (Human) mAb-Biotin

Code No. D092-6

Anti-CD274 (PD-L1) (Human) mAb-Biotin

Availability (in Japan)

10 or more

(In Japan at 01:30,
Aug 20, 2017 in JST)

Size

20 µg/1 mL

Data
  • Flow Cytometry

Clonality Monoclonal Clone MIH3
Isotype (Immunized Animal) Mouse IgG1
Applications
FCM
20 µL (Ready for use.)  
Immunogen (Antigen) full length Human PD-L1 transfected L cells
Reactivity [Gene ID]

Human[29126]

Storage buffer 20 µg/mL in PBS/1% BSA/0.09% NaN3
Storage temp. 4°C Conjugate Biotin Manufacturer MBL
Alternative names B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1
Background Programmed death ligand 1 (PD-L1, also known as CD274/B7-H1), a member of B7 family was identified by searching for molecules that share homology with the immunoglobulin V and C domains of B7-1 and B7-2 among the human cDNA expressed sequence tags in the National Center for Biotechnology Information database. PD-L1 is a ligand for programmed death 1 (PD-1) which belongs to the CD28/CTLA4 subfamily. Although in vitro study indicated that the cross-linking of PD-1 by PD-L1 leads to down-regulation of T-cell responses, some studies have shown that T cells stimulated with low levels of anti-CD3 and immobilized PD-L1-Ig were activated, proliferation and production of IFN-γ, GM-CSF and IL-10 from the T cells were enhanced.
Related products D092-3 Anti-CD274 (PD-L1) (Human) mAb
D132-3 Anti-CD279 (PD-1) (Human) mAb
D132-4 Anti-CD279 (PD-1) (Human) mAb-FITC
D133-3 Anti-CD279 (PD-1) (Human) mAb
D230-3 Anti-CD274 (PD-L1) (Human) mAb
D231-3 Anti-CD273 (PD-L2) (Mouse) mAb
D092-3M2 Anti-CD274 (PD-L1) (Human) mAb (Functional Grade)
D133-3M2 Anti-CD279 (PD-1) (Human) mAb (Functional Grade)
Product category
Research area
Immunology
Cell surface antigens
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  • The availability is based on the information in Japan at 01:30, Aug 20, 2017 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.