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Clip	Code No.	Product					Data
Data Sheet	Isotype	Clone	Conjugate	Size	Price	Availability
	Application			Reactivity		Storage temp.
	D359-3	Anti-IL-38 (IL1F10) (Human) mAb
	Mouse IgG1 κ	H160A	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / ELISA*			Hu		-20°C
	D358-3	Anti-IL-38 (IL1F10) (Human) mAb
	Mouse IgG2bκ	H127C	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / IH* / ELISA*			Hu		-20°C
	M220-3	Anti-HB-EGF mAb
	Mouse IgG1 κ	2-108	Unlabeled	100 µL (1 mg/mL)	￥52,800	1-9
	WB / IP* / IC* / IH / ELISA*			Hu / Rat**		-20°C
	D365-3	Anti-PIWIL2 (MILI) (Mouse) mAb
	Mouse IgG2aκ	3G5-E6	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / IH			Mo / Rat**		-20°C
	D363-3	Anti-Ly6k (Mouse) mAb
	Rat IgG2aκ	mk34	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / FCM / IH*			Hu** / Mo / Rat**		-20°C
	RN017M	Anti-7-methylguanosine (m7G) mAb
	Mouse IgG2aκ	4141-13	Unlabeled	200 µL (1 mg/mL)	￥66,000	10 or more
	IP / IC / ELISA / DB / Other*					-20°C
	RN016M	Anti-7-methylguanosine (m7G)-Cap mAb
	Mouse IgG2aκ	150-15	Unlabeled	200 µL (1 mg/mL)	￥66,000	10 or more
	IP / IC / ELISA / DB					-20°C
	RN019M	Anti-2,2,7-trimethylguanosine (m3G/TMG) mAb
	Mouse IgG2aκ	235-1	Unlabeled	200 µL (1 mg/mL)	￥66,000	10 or more
	IP / IC					-20°C
	M226-3	Anti-ATAD2 (ANCCA) (Human) mAb
	Mouse IgG1 κ	C20-19	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / IC / IH			Hu		-20°C
	D048-3M2	Anti-IL-18 (Mouse) mAb (Functional Grade)
	Rat IgG1	93-10C	Unlabeled	100 µL (1 mg/mL)	￥79,200	10 or more
	IP / NT			Mo		-20°C
	D044-3M2	Anti-IL-18 (Human) mAb (Functional Grade)
	Mouse IgG1 κ	125-2H	Unlabeled	100 µL (1 mg/mL)	￥79,200	10 or more
	IP / NT			Hu		-20°C
	RN014MW	Anti-SFPQ (PSF) mAb
	Mouse IgG2aκ	C23	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / IC / IH			Hu / Mo / Rat / Ham		-20°C
	RN013MW	Anti-Nono (P54NRB) mAb
	Mouse IgG2aκ	C5	Unlabeled	100 µL (1 mg/mL)	￥52,800	1-9
	WB / IP / IC / IH			Mo / Rat / Ham		-20°C
	MEX003-3	Anti-CD81 (TAPA1) mAb
	Mouse IgG2aκ	A103-10	Unlabeled	100 µL (1 mg/mL)	￥66,000	10 or more
	WB / IP / FCM / ELISA			Hu / Ham / Mky		-20°C
	MEX002-3	Anti-CD63 (LAMP-3) mAb
	Mouse IgG2bκ	C047-1	Unlabeled	100 µL (1 mg/mL)	￥66,000	10 or more
	WB / IP / FCM / ELISA			Hu / Mky		-20°C
	MEX001-3	Anti-CD9 mAb
	Mouse IgG2aκ	A100-4	Unlabeled	100 µL (1 mg/mL)	￥66,000	10 or more
	WB / IP / FCM / ELISA / Other*			Hu / Mky		-20°C
	CM004-3	Anti-SynCAM (TSLC1/CADM1) mAb
	Chicken IgY	3E1	Unlabeled	100 µL (1 mg/mL)	￥57,200	10 or more
	WB / IP / FCM / IC* / IH			Hu / Mo* / Rat* / Horse* / Porcine*		-20°C
	CY-M1013	Anti-Phospho-Rb (Ser612) mAb
	Mouse IgG2a	3C11	Unlabeled	100 µg	￥55,000	1-9
	WB / IP / ELISA			Hu		-20°C
	CY-M1015	Anti-Phospho-Rb (Ser807) mAb
	Mouse IgG1	5H12	Unlabeled	100 µg	￥55,000	0 (Contact us)
	WB / IP / ELISA			Hu		-20°C
	CY-M1032	Anti-PCSK9 prodomain (Human) mAb
	Mouse IgG1	KS-2C8	Unlabeled	100 µg	￥55,000	1-9
	WB / IP			Hu		-20°C
	CY-M1033	Anti-PCSK9 (Human) mAb
	Mouse IgG1	KS-4H12	Unlabeled	100 µg	￥55,000	1-9
	WB / IP			Hu		-20°C
	CY-M1035	Anti-NAMPT mAb
	Mouse IgG2a	AF-1E12	Unlabeled	100 µg	￥55,000	1-9
	IP / ELISA			Hu		-20°C
	D044-3	Anti-IL-18 (Human) mAb
	Mouse IgG1 κ	125-2H	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	IP / IC* / ELISA / NT			Hu		-20°C
	D045-3	Anti-IL-18 (Human) mAb
	Rat IgG2a	159-12B	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	IP			Hu		-20°C
	D047-3	Anti-IL-18 (Mouse) mAb
	Rat IgG2a	74	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	IP			Mo		-20°C
	D048-3	Anti-IL-18 (Mouse) mAb
	Rat IgG1	93-10C	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	IP / NT			Mo		-20°C
	D050-3	Anti-CD29 (Integrin β1) (Human) mAb
	Mouse IgG1	AG89	Unlabeled	100 µg	￥38,500	10 or more
	WB / IP / FCM			Hu		冷蔵
	D065-3	Anti-ST2 (Human) mAb
	Mouse IgG1	HB12	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / FCM / IH			Hu		-20°C
	D066-3	Anti-ST2 (Human) mAb
	Mouse IgG1	FB9	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / FCM / ELISA			Hu		-20°C
	D067-3	Anti-ST2 (Human) mAb
	Mouse IgG1	2A5	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / FCM			Hu		-20°C
	D079-3	Anti-TLR4-MD-2 complex (Mouse) mAb
	Rat IgG2aκ	MTS510	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	IP / FCM / Other			Mo		-20°C
	D086-3	Anti-ASC (TMS1) (Human) mAb
	Mouse IgG1	23-4	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / IC* / IH*			Hu		-20°C
	D130-3	Anti-Runx2 (Cbfa1) mAb
	Mouse IgG2bκ	8G5	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP* / IC* / IH* / ELISA* / ChIP* / Co-IP*			Hu / Mo / Rat*		-20°C
	D134-3	Anti-HES1 mAb
	Rat IgG2a	NM1	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / IC / IH*			Hu* / Mo* / Rat		-20°C
	D139-3	Anti-Ring1B mAb
	Mouse IgG2b	3-3	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / IH* / IF* / ChIP*			Hu / Mo / Ham		-20°C
	D147-3	Anti-Abi-1 (Abl interactor 1) mAb
	Mouse IgG1	1B9	Unlabeled	100 µL (1 mg/mL)	￥44,000	1-9
	WB / IP / IC* / IH			Hu / Mo / Rat* / Ham / Dog*		-20°C
	D161-3	Anti-MFG-E8 (Mouse) mAb
	Hamster IgG	2422	Unlabeled	100 µL (1 mg/mL)	￥52,800	1-9
	IP / FCM / IH* / ELISA* / NT*			Mo		-20°C
	D164-3	Anti-NEU3 (Human) mAb
	Mouse IgG1 κ	11B	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP* / IC* / IH*			Hu		-20°C
	D178-3	Anti-CD300a/d (MAIR-I/II) (Mouse) mAb
	Rat IgG1	TX10	Unlabeled	100 µL (1 mg/mL)	￥57,200	1-9
	WB / IP / FCM			Mo		-20°C
	D184-3	Anti-Granulysin (Human) mAb
	Mouse IgG1 κ	RB1	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	IP / FCM / IC / ELISA*			Hu		-20°C
	D185-3	Anti-Granulysin (Human) mAb
	Mouse IgG1 κ	RC8	Unlabeled	100 µL (1 mg/mL)	￥52,800	1-9
	IP / FCM / IC			Hu		-20°C
	D186-3	Anti-Granulysin (Human) mAb
	Mouse IgG2aκ	RF10	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / FCM / IC / IH*			Hu		-20°C
	D190-3	Anti-Aggrus (Podoplanin) (Mouse) mAb
	Rat IgG2a	8F11	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / FCM / IC* / IH			Mo		-20°C
	D198-3	Anti-CD93 (Human) mAb
	Mouse IgG1	mNI-11	Unlabeled	100 µL (1 mg/mL)	￥46,200	10 or more
	IP / FCM / IH / Co-IP*			Hu		-20°C
	D204-3	Anti-CD52 (CAMPATH-1) (Mouse) mAb
	Rat IgG2a	BTG-2G	Unlabeled	100 µL (1 mg/mL)	￥44,000	10 or more
	IP / FCM / Function*			Mo		-20°C
	D210-3	Anti-Histone H2A mAb
	Mouse IgG2b	C10037	Unlabeled	100 µL (1 mg/mL)	￥52,800	1-9
	WB / IP / IC			Hu / Mo / Rat / Ham		-20°C
	D212-3	Anti-Histone H2B mAb
	Mouse IgG2b	C14264	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / IC			Hu / Mo / Rat / Ham		-20°C
	D214-3	Anti-Histone H4 mAb
	Mouse IgG2b	C14691	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / IC			Hu / Mo / Rat / Ham		-20°C
	D217-3	Anti-Desmoglein 3 (Mouse) mAb (No Azide)
	Mouse IgG1	AK9	Unlabeled	100 µL (1 mg/mL)	￥57,200	10 or more
	IP / IC / IH			Mo		冷蔵
	D218-3	Anti-Desmoglein 3 (Mouse) mAb (No Azide)
	Mouse IgG1	AK18	Unlabeled	100 µL (1 mg/mL)	￥57,200	10 or more
	IP* / IC / IH			Hu(w) / Mo		冷蔵
	D219-3	Anti-Desmoglein 3 (Mouse) mAb (No Azide)
	Mouse IgG1	AK23	Unlabeled	100 µL (1 mg/mL)	￥57,200	10 or more
	IP* / IC / IH			Hu / Mo		冷蔵
	D221-3	Anti-Sap155 mAb
	Mouse IgG2b	16	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / IC			Hu / Mo		-20°C
	D266-3	Anti-Mincle (Mouse) mAb
	Rat IgG1 κ	1B6	Unlabeled	100 µL (1 mg/mL)	￥66,000	10 or more
	WB / IP / FCM / Function			Mo		-20°C
	D289-3	Anti-Np95 (Uhrf1) (Mouse) mAb
	Rat IgG2aκ	Th-10a	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP* / FCM* / IC / IH*			Mo		-20°C
	D292-3	Anti-Mincle (Mouse) mAb
	Rat IgG1 κ	4A9	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / FCM / Function			Mo		-20°C
	D299-3	Anti-IDH1-R132H (Human) mAb
	Mouse IgG1 κ	HMab-1	Unlabeled	100 µg/100 µL	￥34,000	10 or more
	WB / IP / IC / IH			Hu / Dog*		-20°C
	D300-3	Anti-IDH1-R132S (Human) mAb
	Mouse IgG1 κ	SMab-1	Unlabeled	100 µL (1 mg/mL)	￥37,400	1-9
	WB / IP / IC / IH			Hu / Dog*		-20°C
	D308-3	Anti-HB-EGF (Human) mAb
	Mouse IgG1 κ	3H4	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / FCM / IC			Hu		-20°C
	D309-3	Anti-IDH1 mAb
	Mouse IgG1 κ	RMab-3	Unlabeled	100 µL (1 mg/mL)	￥37,400	10 or more
	WB / IP / IH			Hu / Ham / Dog*		-20°C
	D320-3	Anti-Podoplanin (Human) mAb
	Rat IgG2aκ	NZ-1.2	Unlabeled	100 µL (1 mg/mL)	￥37,400	10 or more
	WB / IP / FCM / IH			Hu		-20°C
	D321-3	Anti-Podoplanin (Mouse) mAb
	Rat IgG2aκ	PMab-1	Unlabeled	100 µL (1 mg/mL)	￥37,400	1-9
	WB / IP / FCM / IC / IH			Mo		-20°C
	D333-3	Anti-CLOCK (Mouse) mAb
	Mouse IgG1 κ	CLSP3	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP** / ChIP*			Hu / Mo		-20°C
	D334-3	Anti-CLOCK (Mouse) mAb
	Mouse IgG1 κ	CLNT1	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP*			Mo		-20°C
	D345-3	Anti-1-methyladenosine (m1A) mAb
	Mouse IgG2bκ	AMA-2	Unlabeled	100 µL (1 mg/mL)	￥66,000	10 or more
	IP / IC / IH / ELISA** / DB* / Other*					-20°C
	D346-3	Anti-5-methylcytidine (m5C) mAb
	Mouse IgG2aλ	FMC-9	Unlabeled	100 µL (1 mg/mL)	￥66,000	1-9
	IP / IC / IH / ELISA / DB / Other*					-20°C
	D349-3	Anti-CLOCK mAb
	Mouse IgG1 κ	CLSP4	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / IH / ChIP*			Hu / Mo		-20°C
	K0038-3	Anti-CD229 (Ly9) (Human) mAb
	Mouse IgG1 κ	HLy-9.1.25	Unlabeled	100 µL (1 mg/mL)	￥33,000	10 or more
	IP / FCM			Hu		-20°C
	K0055-3	Anti-FHL2 mAb
	Mouse IgG2a	11-134	Unlabeled	100 µL (1 mg/mL)	￥33,000	10 or more
	WB / IP / IC* / IH / ChIP*			Hu / Mo		-20°C
	K0204-3	Anti-Txnip (VDUP1) mAb
	Mouse IgG2b	JY1	Unlabeled	100 µL (1 mg/mL)	￥33,000	10 or more
	WB / IP			Hu / Mo / Rat*		-20°C
	K0205-3	Anti-Txnip (VDUP1) mAb
	Mouse IgG1	JY2	Unlabeled	100 µL (1 mg/mL)	￥33,000	10 or more
	WB / IP / IC* / IH*			Hu / Mo / Rat*		-20°C
	K0218-3	Anti-MICA/B (Human) mAb
	Mouse IgG2aκ	BAMO3	Unlabeled	100 µL (1 mg/mL)	￥63,800	10 or more
	IP / FCM / ELISA			Hu		-20°C
	M001-3	Anti-HS1 mAb
	Mouse IgG1	3A3	Unlabeled	100 µL (1 mg/mL)	￥52,800	1-9
	WB / IP			Hu / Mo / Rat		-20°C
	M010-3	Anti-BAX (Human) mAb
	Mouse IgG2bκ	4F11	Unlabeled	100 µg	￥52,800	10 or more
	WB / IP / FCM / IC / IH			Hu		冷蔵
	M019-3	Anti-Nucleolin mAb
	Mouse IgG1	4E2	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP* / FCM / IC / IH / Other*			Hu / Bov* / Mky* / Dog*		-20°C
	M021-3	Anti-Neuropsin (Mouse) mAb
	Rat IgG2a	MabB5	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / IC* / IH* / Function* / NT*			Mo		-20°C
	M033-3	Anti-FADD mAb
	Mouse IgG1	1F7	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP*			Hu / Mo		-20°C
	M039-3	Anti-Hsp40 mAb
	Mouse IgG2a	2E1	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP			Hu / Mo / Rat		-20°C
	M041-3	Anti-PML (Human) mAb
	Mouse IgG1	1B9	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP* / FCM / IC			Hu		-20°C
	M042-3	Anti-DNA Topoisomerase IIα (Human) mAb
	Mouse IgG2a	1C5	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / FCM / IC / IH			Hu		-20°C
	M050-3	Anti-RCC1 mAb
	Mouse IgG1	3D11	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / IC			Hu / Mo / Rat		-20°C
	M053-3	Anti-Caspase-7 mAb
	Mouse IgG2b	4G2	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP			Hu / Mo / Rat		-20°C
	M055-3	Anti-ORC2 (Human) mAb
	Mouse IgG1 κ	3B7	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / IC			Hu		-20°C
	M058-3	Anti-Caspase-8 (Human) mAb
	Mouse IgG2bκ	5D3	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP			Hu		-20°C
	M067-3	Anti-Apolipoprotein E4 (Human) mAb
	Mouse IgG1	1F9	Unlabeled	100 µg	￥52,800	10 or more
	WB / IP / IH			Hu		冷蔵
	M068-3	Anti-Apolipoprotein E (Human) mAb
	Mouse IgG2a	3D12	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / IH			Hu		-20°C
	M096-3	Anti-CD170 (Siglec-5) (Mouse) mAb
	Rat IgG2b	8D2	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	IP / FCM			Mo		-20°C
	M100-3	Anti-CD11c (Mouse) mAb
	Rat IgG2a	223H7	Unlabeled	100 µL (1 mg/mL)	￥30,800	10 or more
	IP / FCM / IH*			Mo		-20°C
	M101-3	Anti-CD13 (Mouse) mAb
	Rat IgG2b	123H1	Unlabeled	100 µL (1 mg/mL)	￥30,800	1-9
	IP / FCM			Mo		-20°C
	M109-3	Anti-CD61 (gpIIIa) (Mouse) mAb
	Rat IgG2aκ	1-55-4	Unlabeled	100 µL (1 mg/mL)	￥35,200	10 or more
	WB / IP / FCM			Mo		-20°C
	M112-3	Anti-TRAF2 mAb
	Rat IgG2a	6F8	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / FCM*			Hu / Mo / Rat		-20°C
	M133-3	Anti-Atg3 mAb
	Mouse IgG2bκ	3E8	Unlabeled	100 µL (1 mg/mL)	￥52,800	1-9
	WB / IP / IC			Hu / Mo / Rat / Ham		-20°C
	M138-3	Anti-IL-33 (Human) mAb
	Mouse IgG1	5H1	Unlabeled	100 µL (1 mg/mL)	￥44,000	10 or more
	WB / IP			Hu		-20°C
	M143-3	Anti-GFRα1 (Human) mAb
	Mouse IgG2b	3H8	Unlabeled	100 µL (1 mg/mL)	￥44,000	1-9
	IP / FCM			Hu		-20°C
	M147-3	Anti-Borealin (Human) mAb
	Mouse IgG2a	1D11	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / IC			Hu		-20°C
	M152-3	Anti-LC3 mAb
	Mouse IgG1 κ	4E12	Unlabeled	100 µL (2 mg/mL)	￥52,800	10 or more
	WB* / IP / FCM / IC / IH* / Other* / Other*			Hu / Mo / Rat / Ham		-20°C
	M152-3MS	Anti-LC3 mAb for My select sampler set
	Mouse IgG1 κ	4E12	Unlabeled	20 µL (2 mg/mL)	￥13,200	1-9
	WB* / IP / FCM / IC / IH* / Other*			Hu / Mo / Rat / Ham		-20°C
	M154-3	Anti-Atg12 (Human) mAb
	Mouse IgG1 κ	6E5	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	WB / IP / IC			Hu		-20°C
	M158-3	Anti-IL-18 (Rat) mAb
	Mouse IgG2bκ	91D8	Unlabeled	100 µL (1 mg/mL)	￥52,800	10 or more
	IP			Rat		-20°C
	M160-3	Anti-UVRAG mAb
	Mouse IgG1 κ	1H4	Unlabeled	100 µL (1 mg/mL)	￥52,800	1-9
	WB / IP* / IC*			Hu / Mo / Rat / Ham		-20°C
	M161-3	Anti-IL-33 (Mouse) mAb
	Mouse IgG2aκ	4G4	Unlabeled	100 µL (1 mg/mL)	￥52,800	1-9
	WB / IP			Mo		-20°C

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• The availability is based on the information in Japan at 00:05, Jan 17, 2025 in JST.
• The special price is shown in red color.
• Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
• Abbreviations for applications：
  WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
  FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
  ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
  DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
• For applications and reactivity:
  *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
  **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  
• For storage temparature: RT: room temparature
• Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.