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                    Clip Code No. Product Data
                    Data
                    Sheet
                    Isotype Clone Conjugate Size Price Availability
                    Application Reactivity Storage
                    temp.
                    MD-10-A48

                    Anti-Fas (CD95) (Human) mAb-Alexa Fluor™ 488

                    Mouse IgG1 UB2 Alexa Fluor® 488 100 µL (1 mg/mL) ¥63,800 10 or more
                    FCM Hu 4°C
                    D028-3

                    Anti-CD66c (KOR-SA3544) (Human) mAb

                    Mouse IgG1 KOR-SA3544 Unlabeled 100 µL (1 mg/mL) ¥52,800 10 or more
                    WB / FCM Hu -20°C
                    D087-5

                    Anti-GPI-80 (Human) mAb-PE

                    Mouse IgG1 3H9 PE 1 mL (50 tests) ¥44,000 10 or more
                    FCM Hu 4°C
                    D189-1

                    Anti-Aggrus (Podoplanin) (Human) mAb

                    Rat IgG2a YM-1 Unlabeled 100 µL ¥52,800 10 or more
                    WB / FCM / IH Hu 4°C
                    D210-3

                    Anti-Histone H2A mAb

                    Mouse IgG2b C10037 Unlabeled 100 µL (1 mg/mL) ¥52,800 1-9
                    WB / IP / IC Hu / Mo / Rat / Ham -20°C
                    M077-3M2

                    Mouse IgG2b (isotype control) (Functional Grade)

                    Mouse IgG2bκ 3D12 Unlabeled 100 µL (5 mg/mL) ¥66,000 10 or more
                    -20°C
                    M081-4

                    Rat IgG2a (isotype control)-FITC

                    Rat IgG2aκ 2H3 FITC 1mL (50 µg/mL) ¥33,000 1-9
                    FCM 4°C
                    PD010

                    Anti-ATBF1 (D1-120) pAb

                    Rabbit IgG Polyclonal Unlabeled 100 µL ¥52,800 10 or more
                    WB / IP / IC / IH / IF Hu / Mo / Rat -20°C
                    C0004-1

                    In vivo Grade Human IgG4 kappa Isotype Control-CrownVivo

                    Human IgG CB4 Unlabeled 100 µg ¥30,000 0
                    (Contact us)
                    WB / IP / FCM / IH / IF / ELISA / Function Chi -80°C
                    CY-M1023

                    Anti-Phospho-Syntide-2 mAb

                    Mouse IgG2b MS-6E6 Unlabeled 100 µg ¥55,000 10 or more
                    ELISA -20°C
                    M080-5

                    Rat IgG1 (isotype control)-PE

                    Rat IgG1 1H5 PE 50 tests, 1mL (10 µg/mL) ¥33,000 1-9
                    FCM 4°C
                    M081-3M2

                    Rat IgG2a (isotype control) (Functional Grade)

                    Rat IgG2aκ 2H3 Unlabeled 100 µL (5 mg/mL) ¥66,000 10 or more
                    -20°C
                    PM049

                    Anti-β-galactosidase pAb

                    Rabbit IgG polyclonal Unlabeled 100 µL ¥52,800 10 or more
                    WB / IP / IC / IH -20°C
                    PM084

                    Normal Chicken IgY

                    Chicken IgY Polyclonal Unlabeled 200 µL (1 mg/mL) ¥27,500 10 or more
                    FCM -20°C
                    C0001-2

                    In vivo Grade Human IgG1 kappa Isotype Control-CrownVivo

                    Human IgG1 κ CB1 Unlabeled 1 mg ¥75,000 0
                    (Contact us)
                    WB / IP / FCM / IH / IF / ELISA / Function Chi -80°C
                    D055-3

                    Anti-M6a (Mouse) mAb

                    Rat IgG2aκ 321 Unlabeled 100 µL (1 mg/mL) ¥44,000 10 or more
                    FCM / IH / IF* / Other* / Other* Mo -20°C
                    M077-A48

                    Mouse IgG2b (isotype control)-Alexa Fluor™ 488

                    Mouse IgG2bκ 3D12 Alexa Fluor® 488 100 µL (1 mg/mL) ¥33,000 10 or more
                    FCM 4°C
                    M219-3

                    Anti-RORγt mAb

                    Rat IgG2aκ 4H11 Unlabeled 100 µL (1 mg/mL) ¥52,800 1-9
                    WB / IP Hu -20°C
                    C0001-3

                    In vivo Grade Human IgG1 kappa Isotype Control-CrownVivo

                    Human IgG1 κ CB1 Unlabeled 5 mg ¥280,000 0
                    (Contact us)
                    WB / IP / FCM / IH / IF / ELISA / Function Chi -80°C
                    M204-3MS

                    Anti-RFP mAb for My select sampler set

                    Mouse IgG2bκ 1G9 Unlabeled 20 µL (1 mg/mL) ¥11,000 1-9
                    WB Other -20°C
                    M223-3

                    Anti-Ash-tag mAb

                    Mouse IgG1 FLP1C15-2 Unlabeled 100 µL (1 mg/mL) ¥52,800 10 or more
                    WB -20°C
                    M185-3MS

                    Anti-DDDDK-tag mAb for My select sampler set

                    Mouse IgG2aκ FLA-1 Unlabeled 20 µL (1 mg/mL) ¥8,800 0
                    (Contact us)
                    WB / IP / FCM / IC / ChIP* / Co-IP* -20°C
                    M188-3

                    Anti-IL-33 (Mouse) mAb (Functional Grade)

                    Mouse IgG2aκ 2C7 Unlabeled 200 µL (1 mg/mL) ¥88,000 10 or more
                    WB Mo 4°C
                    D292-3M2

                    Anti-Mincle (Mouse) mAb (Functional Grade)

                    Rat IgG1 κ 4A9 Unlabeled 100 µL (1 mg/mL) ¥79,200 1-9
                    Function Mo -20°C
                    M076-5

                    Mouse IgG2a (isotype control)-PE

                    Mouse IgG2aκ 6H3 PE 50 tests, 1mL (10 µg/mL) ¥33,000 1-9
                    FCM 4°C
                    M162-A59

                    Anti-p62 (SQSTM1) (Human) mAb-Alexa Fluor™ 594

                    Mouse IgG1 κ 5F2 Alexa Fluor® 594 100 µL (1 mg/mL) ¥63,800 1-9
                    IC Hu 4°C
                    W194-3

                    Anti-FAM171A1 (Human) mAb

                    Mouse IgG2aκ 2B11G Unlabeled 100 µL (1 mg/mL) ¥52,800 10 or more
                    FCM Hu -20°C
                    D060-3

                    Anti-RCAS1 (Human) mAb

                    Mouse IgM 22-1-1 Unlabeled 100 µL (1 mg/mL) ¥52,800 1-9
                    FCM / IC / IH* Hu -20°C
                    M137-3

                    Anti-HMGB1 (HMG1) mAb

                    Mouse IgG1 4C9 Unlabeled 100 µL (1 mg/mL) ¥52,800 10 or more
                    WB / IF* Hu / Mo / Rat -20°C
                    D212-3

                    Anti-Histone H2B mAb

                    Mouse IgG2b C14264 Unlabeled 100 µL (1 mg/mL) ¥52,800 10 or more
                    WB / IP / IC Hu / Mo / Rat / Ham -20°C
                    M090-4

                    Rat IgG2b (isotype control)-FITC

                    Rat IgG2bκ 3G8 FITC 1mL (50 µg/mL) ¥33,000 1-9
                    FCM 4°C
                    CY-M1033

                    Anti-PCSK9 (Human) mAb

                    Mouse IgG1 KS-4H12 Unlabeled 100 µg ¥55,000 1-9
                    WB / IP Hu -20°C
                    M060-3

                    Anti-Caspase-5 mAb

                    Mouse IgG1 κ 4F7 Unlabeled 100 µL (1 mg/mL) ¥52,800 10 or more
                    WB Hu -20°C
                    CY-P1017

                    Anti-Adiponectin (Acrp30) pAb

                    Rabbit IgG Polyclonal Unlabeled 50 µg ¥44,000 0
                    (Contact us)
                    WB / IP Hu / Mo / Rat -20°C
                    D332-3

                    Anti-Mutated IDH1/2 (Human) mAb

                    Rat IgG2aκ MsMab-2 Unlabeled 100 µL (1 mg/mL) ¥37,400 10 or more
                    WB / IH* / ELISA* Hu -20°C
                    D238-3

                    Anti-MORC3 mAb

                    Mouse IgG1 κ 17A9 Unlabeled 100 µL (1 mg/mL) ¥52,800 1-9
                    WB / IC Hu / Mo / Rat -20°C
                    M077-5

                    Mouse IgG2b (isotype control)-PE

                    Mouse IgG2bκ 3D12 PE 50 tests, 1mL (10 µg/mL) ¥33,000 1-9
                    FCM 4°C
                    C0001-1

                    In vivo Grade Human IgG1 kappa Isotype Control-CrownVivo

                    Human IgG1 κ CB1 Unlabeled 100 µg ¥30,000 0
                    (Contact us)
                    WB / IP / FCM / IH / IF / ELISA / Function Chi -80°C
                    M078-3M2

                    Mouse IgG3 (isotype control) (Functional Grade)

                    Mouse IgG3 6A3 Unlabeled 100 µL (5 mg/mL) ¥66,000 1-9
                    -20°C
                    W013-3

                    Anti-EFEMP1 (Fibulin-3) (Human) mAb

                    Mouse IgG2aκ 2F9A1 Unlabeled 100 µL (1 mg/mL) ¥52,800 10 or more
                    FCM Hu -20°C
                    M100-4

                    Anti-CD11c (Mouse) mAb-FITC

                    Rat IgG2a 223H7 FITC 100 µL (500 µg/mL) ¥33,000 10 or more
                    IP / FCM Mo 4°C
                    W181-3

                    Anti-Apolipoprotein D (Human) mAb

                    Mouse IgG2aκ 2H11L Unlabeled 100 µL (1 mg/mL) ¥52,800 10 or more
                    FCM Hu -20°C
                    MK-15-3

                    Anti-Rb (Human) mAb

                    Mouse IgG2aκ 3H9 Unlabeled 100 µL (1 mg/mL) ¥70,400 1-9
                    WB / IP / IH Hu -20°C
                    MI-11-5

                    Anti-Bromodeoxyuridine mAb-PE

                    Mouse IgG1 2B1 PE 1 mL (50tests) ¥33,000 10 or more
                    FCM Hu 4°C
                    M076-A64

                    Mouse IgG2a (isotype control)-Alexa Fluor™ 647

                    Mouse IgG2aκ 6H3 Alexa Fluor® 647 100 µL (1 mg/mL) ¥33,000 10 or more
                    FCM 4°C
                    M090-3

                    Rat IgG2b (isotype control)

                    Rat IgG2bκ 3G8 Unlabeled 100 µL (1 mg/mL) ¥27,500 10 or more
                    IP / FCM -20°C
                    D308-3

                    Anti-HB-EGF (Human) mAb

                    Mouse IgG1 κ 3H4 Unlabeled 100 µL (1 mg/mL) ¥52,800 10 or more
                    WB / IP / FCM / IC Hu -20°C
                    M176-A64

                    Anti-EEA1 mAb-Alexa Fluor™ 647

                    Mouse IgG2aκ 3C10 Alexa Fluor® 647 100 µL (1 mg/mL) ¥63,800 1-9
                    IC Hu / Mo / Rat 4°C
                    D028-5

                    Anti-CD66c (KOR-SA3544) (Human) mAb-PE

                    Mouse IgG1 KOR-SA3544 PE 1 mL (50 tests) ¥44,000 10 or more
                    FCM Hu 4°C
                    K0211-3

                    Anti-TLR2 (CD282) (Mouse) mAb

                    Mouse IgG2a mT2.7 Unlabeled 100 µL (1 mg/mL) ¥33,000 10 or more
                    FCM Mo -20°C
                    CY-M1032

                    Anti-PCSK9 prodomain (Human) mAb

                    Mouse IgG1 KS-2C8 Unlabeled 100 µg ¥55,000 0
                    (Contact us)
                    WB / IP Hu -20°C
                    D204-5

                    Anti-CD52 (CAMPATH-1) (Mouse) mAb-PE

                    Rat IgG2aκ BTG-2G PE 1 mL (50 tests) ¥44,000 10 or more
                    FCM Mo 4°C
                    M082-3M2

                    Rat IgG2c (isotype control) (Functional Grade)

                    Rat IgG2c 6E12 Unlabeled 100 µL (5 mg/mL) ¥66,000 10 or more
                    -20°C
                    C0006-5

                    In vivo Grade Mouse IgG2a kappa Isotype Control-CrownVivo

                    Mouse IgG2aκ CB6 Unlabeled 20 mg ¥720,000 0
                    (Contact us)
                    WB / IP / FCM / IH / IF / ELISA / Function Chi -80°C
                    M081-8

                    Rat IgG2a (isotype control)-Agarose

                    Rat IgG2aκ 2H3 Agarose Gel:200 µL (Slurry:400 µL) ¥38,500 10 or more
                    IP 4°C
                    PM076

                    Anti-Syntaxin-17 (Human) pAb

                    Rabbit Ig (aff.) Polyclonal Unlabeled 100 µL ¥52,800 1-9
                    WB / IP / IC Hu -20°C
                    M191-A64

                    Anti-FcεR1γ (FcRγ) (Mouse) mAb-Alexa Fluor™ 647

                    Mouse IgG1 κ 1D6 Alexa Fluor® 647 100 µL (1 mg/mL) ¥63,800 10 or more
                    FCM / IC Mo 4°C
                    D184-3

                    Anti-Granulysin (Human) mAb

                    Mouse IgG1 κ RB1 Unlabeled 100 µL (1 mg/mL) ¥52,800 10 or more
                    IP / FCM / IC / ELISA* Hu -20°C
                    458

                    Anti-IgG (H+L chain) (Rabbit) pAb-HRP

                    Goat Fab'(aff.) Polyclonal HRP 1 mL ¥20,000 10 or more
                    WB / IH* / ELISA / Co-IP* Rab 4°C
                    C0004-4

                    In vivo Grade Human IgG4 kappa Isotype Control-CrownVivo

                    Human IgG CB4 Unlabeled 10 mg ¥450,000 0
                    (Contact us)
                    WB / IP / FCM / IH / IF / ELISA / Function Chi -80°C
                    311

                    Anti-GST-P pAb

                    Rabbit IgG Polyclonal Unlabeled 100 µL ¥35,200 10 or more
                    WB / IH Hu / Mo / Rat -20°C
                    D079-3

                    Anti-TLR4-MD-2 complex (Mouse) mAb

                    Rat IgG2aκ MTS510 Unlabeled 100 µL (1 mg/mL) ¥52,800 10 or more
                    IP / FCM / Other Mo -20°C
                    M215-6

                    Anti-V5-tag mAb-Biotin

                    Mouse IgG2bκ OZA3 Biotin 50 µL ¥19,800 10 or more
                    WB / ELISA 4°C
                    M240-3

                    Anti-PE mAb

                    Mouse IgG2aκ C27-6 Unlabeled 100 µL (500 µg/mL) ¥27,500 10 or more
                    Other -20°C
                    W080-3

                    Anti-ADAMTS1 (Human) mAb

                    Mouse IgG2aκ 2B9CB6 Unlabeled 100 µL (1 mg/mL) ¥52,800 10 or more
                    FCM Hu -20°C
                    W321-3

                    Anti-FGFRL1 (Human) mAb

                    Mouse IgG2bκ 9A1A10 Unlabeled 100 µL (1 mg/mL) ¥52,800 1-9
                    FCM Hu -20°C
                    C0020-2

                    In vivo Grade Human IgG1 (D265A) kappa Isotype Control-CrownVivo

                    Human IgG1 κ CB13 Unlabeled 1 mg ¥75,000 1-9
                    WB / IP / FCM / IH / IF / ELISA / Function Chi -80°C
                    W164-3

                    Anti-RHBDD3 (Human) mAb

                    Mouse IgG2aκ 4A8D Unlabeled 100 µL (1 mg/mL) ¥52,800 10 or more
                    FCM Hu -20°C
                    BMP046

                    Anti-SLC6A6 (TAUT) (Human) pAb

                    Rabbit Ig (aff.) polyclonal Unlabeled 50 µL ¥66,000 1-9
                    WB* / FCM / IC / IH Hu / Other* -20°C
                    M080-A64

                    Rat IgG1 (isotype control)-Alexa Fluor™ 647

                    Rat IgG1 1H5 Alexa Fluor® 647 100 µL (1 mg/mL) ¥33,000 10 or more
                    FCM 4°C
                    M186-3MS

                    Anti-LC3 mAb for My select sampler set

                    Mouse IgG2aκ 8E10 Unlabeled 20 µL (1 mg/mL) ¥13,200 1-9
                    WB / IP* Hu / Mo / Rat / Ham -20°C
                    C0006-2

                    In vivo Grade Mouse IgG2a kappa Isotype Control-CrownVivo

                    Mouse IgG2aκ CB6 Unlabeled 1 mg ¥75,000 0
                    (Contact us)
                    WB / IP / FCM / IH / IF / ELISA / Function Chi -80°C
                    C0001-5

                    In vivo Grade Human IgG1 kappa Isotype Control-CrownVivo

                    Human IgG1 κ CB1 Unlabeled 20 mg ¥720,000 0
                    (Contact us)
                    WB / IP / FCM / IH / IF / ELISA / Function Chi -80°C
                    K0055-3

                    Anti-FHL2 mAb

                    Mouse IgG2a 11-134 Unlabeled 100 µL (1 mg/mL) ¥33,000 10 or more
                    WB / IP / IC* / IH / ChIP* Hu / Mo -20°C
                    M047-A59

                    Anti-Myc-tag mAb-Alexa Fluor™ 594

                    Mouse IgG1 κ PL14 Alexa Fluor® 594 100 µL (1 mg/mL) ¥63,800 10 or more
                    IC 4°C
                    C0004-2

                    In vivo Grade Human IgG4 kappa Isotype Control-CrownVivo

                    Human IgG CB4 Unlabeled 1 mg ¥75,000 0
                    (Contact us)
                    WB / IP / FCM / IH / IF / ELISA / Function Chi -80°C
                    D328-3

                    Anti-IDH2-R172K (Human) mAb

                    Rat IgG2bκ KMab-1 Unlabeled 100 µL (1 mg/mL) ¥37,400 10 or more
                    WB / IC* Hu / Dog* -20°C
                    C0001-4

                    In vivo Grade Human IgG1 kappa Isotype Control-CrownVivo

                    Human IgG1 κ CB1 Unlabeled 10 mg ¥450,000 0
                    (Contact us)
                    WB / IP / FCM / IH / IF / ELISA / Function Chi -80°C
                    D067-5

                    Anti-ST2 (Human) mAb-PE

                    Mouse IgG1 2A5 PE 1 mL (50 tests) ¥55,000 10 or more
                    WB / IP / FCM Hu 4°C
                    W158-3

                    Anti-HEXA (Human) mAb

                    Mouse IgG2aκ 2D7C1C Unlabeled 100 µL (1 mg/mL) ¥52,800 10 or more
                    FCM Hu -20°C
                    D198-5

                    Anti-CD93 (Human) mAb-PE

                    Mouse IgG1 mNI-11 PE 1 mL (50 tests) ¥44,000 10 or more
                    FCM Hu 4°C
                    D186-3

                    Anti-Granulysin (Human) mAb

                    Mouse IgG2aκ RF10 Unlabeled 100 µL (1 mg/mL) ¥52,800 10 or more
                    WB / IP / FCM / IC / IH* Hu -20°C
                    M157-3

                    Anti-IL-18 (Rat) mAb

                    Mouse IgG2bκ 21A12 Unlabeled 100 µL (1 mg/mL) ¥52,800 1-9
                    WB Mo(w) / Rat -20°C
                    W210-3

                    Anti-SDF4 (Human) mAb

                    Mouse IgG2aκ 148B10H3 Unlabeled 100 µL (1 mg/mL) ¥52,800 10 or more
                    FCM Hu -20°C
                    311-H

                    Anti-GST-P pAb

                    Rabbit IgG Polyclonal Unlabeled 6 mL ¥32,000 10 or more
                    IH Hu / Rat 4°C
                    D060-3H

                    Anti-RCAS1 (Human) mAb

                    Mouse IgM 22-1-1 Unlabeled 6 mL ¥32,000 0
                    (Contact us)
                    IC Hu 4°C
                    C0002-4

                    In vivo Grade Human IgG2 kappa Isotype Control-CrownVivo

                    Human IgG2κ CB2 Unlabeled 10 mg ¥450,000 0
                    (Contact us)
                    WB / IP / FCM / IH / IF / ELISA / Function Chi -80°C
                    BMP043

                    Anti-SLC9A7 (NHE7) (Human) pAb

                    Rabbit Ig (aff.) Polyclonal Unlabeled 50 µL ¥66,000 1-9
                    WB / FCM / IC / IH Hu -20°C
                    PM070

                    Anti-E-tag pAb

                    Rabbit Ig (aff.) Polyclonal Unlabeled 100 µL ¥35,200 1-9
                    WB / IP -20°C
                    C0005-1

                    In vivo Grade Mouse IgG1 kappa Isotype Control-CrownVivo

                    Mouse IgG1 κ CB5 Unlabeled 100 µg ¥30,000 0
                    (Contact us)
                    WB / IP / FCM / IH / IF / ELISA / Function Chi -80°C
                    K0213-3

                    Anti-TLR9 (CD289) mAb

                    Mouse IgG2a 5G5 Unlabeled 100 µL (1 mg/mL) ¥33,000 10 or more
                    FCM Hu / Mo -20°C
                    MD-06-3

                    Anti-PI3-kinase (p85α) mAb

                    Mouse IgG1 AB6 Unlabeled 100 µL (1 mg/mL) ¥35,200 10 or more
                    WB / IP / IC Hu / Mo / Rat -20°C
                    PM022

                    Anti-T7-tag pAb

                    Rabbit Ig (aff.) Polyclonal Unlabeled 100 µL ¥35,200 10 or more
                    WB / IP / ChIP* -20°C
                    C0006-1

                    In vivo Grade Mouse IgG2a kappa Isotype Control-CrownVivo

                    Mouse IgG2aκ CB6 Unlabeled 100 µg ¥30,000 0
                    (Contact us)
                    WB / IP / FCM / IH / IF / ELISA / Function Chi -80°C
                    C0002-1

                    In vivo Grade Human IgG2 kappa Isotype Control-CrownVivo

                    Human IgG2κ CB2 Unlabeled 100 µg ¥30,000 0
                    (Contact us)
                    WB / IP / FCM / IH / IF / ELISA / Function Chi -80°C
                    PM084-4

                    Normal Chicken IgY-FITC

                    Chicken IgY Polyclonal FITC 100 µL (1 mg/mL) ¥33,000 10 or more
                    FCM Rat** 4°C
                    M042-3

                    Anti-DNA Topoisomerase IIα (Human) mAb

                    Mouse IgG2a 1C5 Unlabeled 100 µL (1 mg/mL) ¥52,800 1-9
                    WB / IP / FCM / IC / IH Hu -20°C
                    D065-3

                    Anti-ST2 (Human) mAb

                    Mouse IgG1 HB12 Unlabeled 100 µL (1 mg/mL) ¥52,800 10 or more
                    WB / IP / FCM / IH Hu -20°C
                    M138-3

                    Anti-IL-33 (Human) mAb

                    Mouse IgG1 5H1 Unlabeled 100 µL (1 mg/mL) ¥44,000 10 or more
                    WB / IP Hu -20°C
                    PD004

                    Anti-MBP (Myelin Basic Protein) pAb

                    Rabbit IgG Polyclonal Unlabeled 100 µL ¥33,000 10 or more
                    WB Hu* / Mo / Rat* -20°C

                    First Previous 4 5 6 7 8 Next Last

                    • The availability is based on the information in Japan at 17:00, Mar 11, 2026 in JST.
                    • The special price is shown in red color.
                    • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
                    • Abbreviations for applications:
                      WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
                      FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
                      ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
                      DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
                    • For applications and reactivity:
                      *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
                      **: The use is reported from the licenser (Under evaluation or not tested by MBL).
                    • For storage temparature: RT: room temparature
                    • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.