Magnosphere™ MS160/Tosyl & MS300/Tosyl are magnetic particles especially for high purity bioseparation. The surface of these particles are coated with hydrophilic polymer for reducing non-specific binding and are activated with p-toluene sulfonyl (tosyl) group. The Tosyl group enables to immobilize ligands such as antibody without using coupling reagents. The activated Tosyl group is eliminated though a coupling reaction, the surface of the particles became hydrophilic to reduce non-specific binding.
Uniform particle size and superparamagnetic property of the Magnosphere™ MS160/Tosyl & MS300/Tosyl provide good magnetic separation and re-suspension response.
● Uniform particle diameter
● High-speed magnetic response
● Low non-specific binding
|Particle size||1.5 µm||3 µm|
|Surface carboxyl density||150 nmol/mg beads approx.||80 nmol/mg beads approx.|
|Ligand coupling||Covalent coupling||Covalent coupling|
Magnosphere is a trademark of JSR corporation.