Code No. |
Product name |
Synonyms |
Reactivity |
Applications |
Function, localization |
RN122PW
|
Anti-ALKBH5 pAb
|
|
Hu/ Mo |
WB/ IP |
ALKBH5 is one of mammalian m6A demethylase, localized in nuclear speckles, catalyzes the direct removal of m6A modification on nuclear RNA and its demethylation affects RNA processing and RNA export.
|
RN001P |
Anti-EIF4E pAb |
|
Hu/ Mo/ Rat/ Ham |
WB/ IP/ RIP/ IC/ IF |
EIF4E, one of the translation-intiation factor, binds to m7G cap structure. It is also related to export of mRNA from nucleus to cytoplasm. |
RN006M |
Anti-EIF4E mAb |
|
Hu/ Mo/ Rat/ Ham |
WB/ IP/ RIP |
EIF4E, one of the translation-intiation factor, binds to m7G cap structure. It is also related to export of mRNA from nucleus to cytoplasm. |
RN004P |
Anti-ELAVL1 (HuR) pAb |
HuR |
Hu/ Mo/ Rat/ Ham |
WB/ IP/ RIP/ IC/ IF |
ELAVL1/HuR, a ubiquitously expressed protein, binds to both poly(A) and AU-rich element of mRNA. It is reported that HuR regulates mRNA export via shuttling between nucleus and cytoplasm. |
RN007M |
Anti-ELAVL1 (HuR) mAb |
HuR |
Hu/ Mo/ Rat/ Ham |
WB/ IP/ RIP |
ELAVL1/HuR, a ubiquitously expressed protein, binds to both poly(A) and AU-rich element of mRNA. It is reported that HuR regulates mRNA export via shuttling between nucleus and cytoplasm. |
RN016P |
Anti-FMR1 pAb |
FMRP |
Hu/ Mo/ Rat |
WB/ IP/ RIP |
FMR1 is necessary for neurogenesis and strongly binds to poly(G) sequenses. The expanded CGG repeats within the FMR1 genes is found in Fragile X syndrome patients.
|
RN048PW |
Anti-G3BP1 pAb |
G3BP |
Hu |
WB/ IP |
G3BP1, a DNA/RNA helicase, is related to a stress granule formation. It is also involved in mRNA export via interaction with nuclear pore complex. |
RN114PW |
Anti-HNRNPA1 pAb |
|
Hu/ Mo/ Rat/ Ham(w) |
WB/ IP |
HNRNPA1 is a multi-functional DNA/RNA binding protein involved in transcription, pre-mRNA splicing, stability, translation and miRNA biogenesis. HNRNPA1 shuttles between nucleus and cytoplasm and is also involved in nuclear export. |
RN052PW |
Anti-HNRNPC pAb |
|
Hu/ Mo |
WB/ IP |
HNRNPC is related to nuclear exprot of mRNAs via binding to both cap binding complex and neighborhood of cap structure of mRNA, of which the length is more than 200 nt. |
RN019P |
Anti-HNRNPK pAb |
HNRPK |
Hu/ Mo/ Rat |
WB/ IP/ RIP/ IC* |
HNRNPK, one of the components of hnRNP complex, shuttles between nucleus and cytoplasm. It is related to splicing, transport and translational regulation of mRNA. |
RN001M |
Anti-IGF2BP1 (IMP1) mAb |
IMP1, ZBP1 |
Hu/ Mo |
WB/ IP/ RIP |
Together with FMRP, IGF2BP1 binds to β-actin mRNA and trasnports it from nucleus to cytoplasm. |
RN007P |
Anti-IGF2BP1 (IMP1) pAb |
IMP1, ZBP1 |
Hu/ Mo |
WB/ IP/ RIP/ IC/ IF |
Together with FMRP, IGF2BP1 binds to β-actin mRNA and trasnports it from nucleus to cytoplasm. |
RN008P |
Anti-IGF2BP2 (IMP2) pAb |
IMP2 |
Hu/ Mo/ Rat |
WB/ IP/ RIP/ IC/ IF |
IGF2BP2 binds to the UTR of IGF2 leader 3 mRNA, which is related to development and proliferation, and regulates its translation. |
RN009P |
Anti-IGF2BP3 (IMP3) pAb |
IMP3 |
Hu/ Mo |
WB/ IP/ RIP |
IGF2BP3 binds to the 5'-UTR of IGF2 leader 3 mRNA, which is related to development and proliferation, and regulates its translation. |
RN009M |
Anti-PABPC1 mAb |
PABP1 |
Hu/ Ham |
WB/ IP/ RIP/ IC |
PABPC1 shuttles between nucleus and cytoplasm. It has been reported that PABPC1 is translocated in nucleus in viral infection and may be involved in viral RNA or host mRNA processing and/or export. |
RN080PW |
Anti-SRSF3 (SRp20) pAb |
SRp20 |
Hu/ Mo/ Rat/ Ham |
WB/ IP/ IC/ IF |
SRSF3/SRp20 shuttles between nucleus and cytoplasm. It is related to transport of histone mRNA by binding to TAP together with SRSF7. |
RN082PW |
Anti-SRSF5 (SRP40) pAb |
SRP40 |
Hu/ Mo/ Rat/ Ham |
WB/ IP |
SRSF5/SRp40 is involved in transport of non-spliced gag-pol mRNA and partially spliced env mRNA of HIV-1. |
RN079PW |
Anti-SRSF7 (9G8) pAb |
9G8 |
Hu/ Mo/ Ham |
WB/ IP |
SRSF7/9G8 shuttles between nucleus and cytoplasm. It is related to transport of histone mRNA through interaction with TAP/NXF1. |
RN012P |
Anti-STAU1 (Human) pAb |
|
Hu |
WB/ IP/ RIP |
STAU1 forms RNA granules in neuronal cells. It is reported that STAU1 regulates export and localization of mRNA via binding to dsRNAs and microtubles. |
RN013P |
Anti-STAU2 (Human) pAb |
|
Hu |
WB/ IP/ RIP |
STAU2 is highly homologous to STAU1, but their function may be different because they do not co-localize in neuronal cells. It shuttles between nucleus and cytoplasm, however, the function in detail is unknown. |
RN107PW |
Anti-TARDBP (TDP-43) pAb |
TDP-43 |
Hu/ Mo/ Ham |
WB/ IP |
TARDBP (TDP-43) is a nuclear DNA/RNA binding protein involved in mRNA splicing, nuclear export, stability, miRNA biogenesis and transcriptional repression. TARDBP is mainly localized in nucleus, however, it shuttles between nucleus and cytoplasm. |