Kit, protein, vector, etc detailed product information

Code No.	U-C006-01
Recombinant murine CTLA4-ECD
Only available for the customers in Singapore, Taiwan and South Korea Storage and Stability: Recombinant CTLA4-ECD should be stored at -80℃ (stable for at least 1 year). The protein is stored in PBS. After thawing it should be stored in appropriate small aliquots at -20℃ or -80℃ (stable for at least 2 months). Production platform: HEK293 cells using the rPEx™ recombinant protein production platform. Datasheet URL: https://products.ipatherapeutics.com/product/c006/
Price	¥112,000
Size	100 µg
Availability (in Japan)	0 (Contact us) （In Japan at 17:00, Mar 19, 2025 in JST）
Storage temp.	-80°C
Manufacturer	ImmunoPrecise Antibodies (Europe) BV
Alternative names	cytotoxic T-lymphocyte protein 4 isoform, CTLA4-TM, cytotoxic T-lymphocyte-associated serine esterase-4, cytotoxic T-lymphocyte-associated antigen 4, cytotoxic T-lymphocyte protein 4, ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4, cytotoxic T-lymphocyte antigen 4, CD152 isoform, cytotoxic T lymphocyte associated antigen 4 short spliced form
Background	Product description: CTLA4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. Residues 38-162 of murine CTLA4, containing the extracellular domain - ECD -, were cloned, the protein was over-expressed in HEK293 cells and was purified to homogeneity. The calculated molecular weight of recombinant murine CD40-ECD is 15.1 kDa and it contains an C-terminal hexahistidine tag. Reference sequences: Swiss-prot P9793
Product category	Research area:Immunology Cell surface antigens

The availability is based on the information in Japan at 17:00, Mar 19, 2025 in JST.
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For storage temparature: RT: room temparature
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