Kit, protein, vector, etc detailed product information

Code No. CY-1251V2
CycLex® NAMPT Colorimetric Assay Kit Ver.2
Price ¥88,000
Size 100 Assays
Availability (in Japan) 10 or more
(In Japan at 17:00, Apr 18, 2024 in JST)
Components NAMPT Assay Buffer (20X), WST-1, ADH (alcohol dehydrogenase), Diaphorase, EtOH Solution, ATP, NMNAT1, Nicotinamide, PRPP, NAMPT
Intended use This Kit detects nicotinamide phosphoribosyltransferase (NAMPT) activity in recombinant NAMPT or endogenous NAMPT immunoprecipitated from cell extract.
Storage temp. -80°C
Manufacturer MBL
Sample Recombinant NAMPT, NAMPT immunoprecipitated from cell lysates
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CY-1151V2 CycLex® SIRT1/Sir2 Deacetylase Fluorometric Assay Kit Ver.2
CY-1152V2 CycLex® SIRT2 Deacetylase Fluorometric Assay Kit Ver.2
CY-1153V2 CycLex® SIRT3 Deacetylase Fluorometric Assay Kit Ver.2
CY-1156V2 CycLex® SIRT6 Deacetylase Fluorometric Assay Kit Ver.2
CY-1158V2 CycLex® HDAC8 Deacetylase Fluorometric Assay Kit Ver.2
CY-M1035 Anti-NAMPT mAb
Product category Research area:Cancer Metabolism Drug discovery Circadian rhythm
Data



Citations
  1. Ogino Y et al. Cross resistance to diverse anticancer nicotinamide phosphoribosyltransferase inhibitors induced by FK866 treatment. Oncotarget. 9, 16451-16461 (2018)(PMID:29662658)
  1. Korotchkina L et al. OT-82, a Novel Anticancer Drug Candidate That Targets the Strong Dependence of Hematological Malignancies on NAD Biosynthesis. Leukemia. in press(PMID:31896781)
References
  1. Vedantham S et al. Aldose reductase drives hyperacetylation of Egr-1 in hyperglycemia and consequent upregulation of proinflammatory and prothrombotic signals. Diabetes. 63, 761-74 (2014)(PMID: 24186862
  2. Laiguillon MC et al. Expression and function of visfatin (Nampt), an adipokine-enzyme involved in inflammatory pathways of osteoarthritis. 16, R38 (2014)(PMID: 24479481
  3. Adams DJ et al. NAMPT is the cellular target of STF-31-like small-molecule probes. ACS Chem Biol. 9, 2247-54 (2014)(PMID: 25058389
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  • For storage temparature: RT: room temparature
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