Kit, protein, vector, etc detailed product information

Code No. CY-1170
CycLex® CK2(Casein kinase II) Kinase Assay/Inhibitor Screening Kit
Price ¥99,000
Size 96 assays
Availability (in Japan) 1-9
（In Japan at 00:05, Apr 25, 2024 in JST）
Components Microplate, 10x Wash Buffer, Kinase Buffer, 20x ATP, HRP conjugated Detection Antibody, Substrate Reagent, Stop Solution
Intended use This Kit designed to measure the activities of purified CK2 for the rapid and sensitive evaluation of inhibitors or activators.
Storage temp. 4°C
Manufacturer MBL
Related products CY-E1170-1 CK2 (alpha/beta) Positive Control
Product category Research area:Drug discovery Signal transduction
Citations
  1. Wang G et al. Protein B23/Nucleophosmin/Numatrin nuclear dynamics in Relation to Protein Kinase CK2 and Apoptotic Activity in Prostate Cells. Biochemistry, 49: 3842-3852 (2010)(PMID:20387789)
  1. Oinuma I et al. Semaphorin 4D/Plexin-B1 Stimulates PTEN Activity through R-Ras GTPase-activating Protein Activity, Inducing Growth Cone Collapse in Hippocampal Neurons. J Biol Chem. 285, 28200-28209 (2010)(PMID:20610402)
  1. Lee WH et al. Casein kinase 2 regulates the mRNA-destabilizing activity of tristetraprolin. J Biol Chem. 286, 21577-21587 (2011)(PMID:21507959)
  1. Lee HR et al. Attenuation of β-amyloid-induced tauopathy via activation of CK2α/SIRT1: targeting for cilostazol. J Neurosci Res. 92, 206-17 (2014)(PMID:24254769)
  1. Jung EB et al. Casein kinase 2 inhibition attenuates cholesterol oxidation product-induced apoptosis by suppressing the activation of the mitochondrial pathway and the caspase-8- and bid-dependent pathways. Neurochem Int. 65, 30-9 (2014)(PMID:24398405)
  1. de Thonel A et al. Regulation of the proapoptotic functions of prostate apoptosis response-4 (Par-4) by casein kinase 2 in prostate cancer cells. Cell Death Dis. 5, e1016 (2014)(PMID:24457960)
  1. Lee YS et al. Helicobacter pylori induces cell migration and invasion through casein kinase 2 in gastric epithelial cells. Helicobacter. 19, 465-75 (2014)(PMID:25052887)
  1. Zhang Q et al. CK2 Phosphorylating I2PP2A/SET Mediates Tau Pathology and Cognitive Impairment. Front Mol Neurosci. 11, 146 (2018)(PMID:29760653)
  1. Floris A et al. Star-related lipid transfer protein 10 (STARD10): a novel key player in alcohol-induced breast cancer progression. J Exp Clin Cancer Res. 38, 4. (2019)(PMID:30611309)
  1. Im J, Nho RS. Fibroblasts from patients with idiopathic pulmonary fibrosis are resistant to cisplatin-induced cell death via enhanced CK2-dependent XRCC1 activity. Apoptosis. 24, 499-510 (2019) (PMID:30850922)
  • The availability is based on the information in Japan at 00:05, Apr 25, 2024 in JST.
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