Code No. |
CY-1083 |
CycLex® c-Src Kinase Assay/Inhibitor Screening Kit
|
Price |
¥64,900
|
Size |
96 assays |
Availability (in Japan) |
0 (Contact us)
(In Japan at 00:05, Mar 19, 2025 in JST)
|
Components |
Microplate, 10X Wash Buffer, Kinase Buffer, 20X ATP HRP conjugated Detection Antibody Substrate Reagent, Stop Solution |
Intended use |
This Kit is designed to measure the activities of recombinant catalytic domain of c-Src for the rapid and sensitive evaluation of inhibitors or activators. |
Storage temp. |
4°C |
Manufacturer |
MBL |
Related products |
CY-E1083 c-Src Positive Control
|
Product category |
Research area:Drug discovery Signal transduction |
Citations |
- Takuma Matsubara, Fumiyo Ikeda, Kenji Hata, Masako Nakanishi, Masato Okada, Hisataka Yasuda, Riko Nishimura, Toshiyuki Yoneda; Cbp Recruitment of Csk Into Lipid Rafts is Critical to c-Src Kinase Activity and Bone Resorption in Osteoclasts. Journal of Bone and Mineral Research, 25: 1068-1076, 2010(PMID:19874196)
- Al-Wadei MH et al. Gamma-amino butyric acid (GABA) prevents the induction of nicotinic receptor-regulated signaling by chronic ethanol in pancreatic cancer cells and normal duct epithelia. Cancer Prev Res. 6, 139-48 (2013)(PMID:23213073)
- Kang Y et al. Anti-angiogenic activity of macrolactin A and its succinyl derivative is mediated through inhibition of class I PI3K activity and its signaling. Arch Pharm Res. 38, 249-60 (2015)(PMID:25547980)
- Gautam J et al. Down-regulation of cathepsin S and matrix metalloproteinase-9 via Src, a non-receptor tyrosine kinase, suppresses triple-negative breast cancer growth and metastasis. Exp Mol Med. 50, 118 (2018)(PMID:30185799)
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