Price
¥124,000
Availability (in Japan)
0
(Contact us)
(In Japan at 00:05,
Feb 8, 2025 in JST)
Size
100 µg
Only available for the customers in Singapore, Taiwan and South Korea
Storage and Stability:Storage temp. | -80°C | Manufacturer | ImmunoPrecise Antibodies (Europe) BV | ||
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Alternative names | Von Willebrand antigen II, Von Willebrand Factor, F8VWF | ||||
Background | Product description: Human Von Willebrand Factor (VWF) is a multimeric glycoprotein, which is involved in binding coaggulaion factor VIII and in adhesion of platelets at sites of vascular damage. In this process the platelet receptor glycoprotein Ib-IX-V complex binds to the VWF-A1 domain. The VWF-A1 variant in this product contains longer N- and C-terminal poly-peptides (with 5 O-linked glycosylation sites), which prevent spontaneous binding of the VWF-A1 domain to platelet receptor GpIb-IX-V complex. Residues 1238-1481 of human VWF were cloned, the protein was over-expressed and was purified to homogeneity. The calculated molecular weight of recombinant human VWF-A1 domain is 27.4 kDa. Reference sequences: Swiss-prot P04275 |
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