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HOME > Product search results > Code No. U-U001-01 Recombinant human UPAR-(his)N

Code No. U-U001-01

Recombinant human UPAR-(his)N

Price

¥118,000

Availability (in Japan)

0
(Contact us)

(In Japan at 00:05,
Feb 17, 2025 in JST)

Size

100 µg

Only available for the customers in Singapore, Taiwan and South Korea

Storage and Stability:
UPAR-(his)N should be stored at -80℃ (stable for at least 1 year). The buffer is PBS without preservative. After thawing it should be stored in appropriate small aliquots at -20℃ or -80℃ (stable for at least 2 months).

Production platform:
HEK293 cells using the rPEx™ recombinant protein production platform.

Datasheet URL:
https://products.ipatherapeutics.com/product/u001/
Storage temp. -80°C Manufacturer ImmunoPrecise Antibodies (Europe) BV
Alternative names UPAR, CD87, urokinase plasminogen activator surface receptor, monocyte activation antigen Mo3, urokinase plasminogen activator surface receptor, u-plasminogen activator receptor form 2, urokinase-type plasminogen activator (uPA) receptor
Background Product description:
This protein is a receptor for urokinase plasminogen activator. It is bound to the plasma membrane via a GPI anchor. However, a soluble protein is also produced in some cell types. It plays a role in localizing and promoting plasmin formation by binding both the proprotein and mature forms of urokinase plasminogen activator (U-PA) and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. 
The mature protein of human UPAR, residues 23 - 335 was over-expressed in HEK293EBNA1 cells and purified to homogeneity. The protein has a C-terminal pre-peptide, residues 306-335, which are removed in the mature protein, 5 potential N-linked glycosylation sites, and 1 GPI-anchor amidated glycine residue. The protein contains a N-terminal hexahistidine tag. The calculated molecular weight without glycosylation of recombinant human UPAR, residues 23 - 335 including hexahistidine tag, is 36.1 kDa.

Reference sequences: Swiss-prot Q03405
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