Recombinant human CTLA4-ECD

Price

¥112,000

Availability (in Japan)

0
(Contact us)

（In Japan at 17:00,
Feb 17, 2025 in JST）

Size

100 µg

Data Sheet

SDS

Only available for the customers in Singapore, Taiwan and South Korea

Storage and Stability:
Recombinant CTLA4-ECD should be stored at -80℃ (stable for at least 1 year). The protein is stored in PBS. After thawing it should be stored in appropriate small aliquots at -20℃ or -80℃ (stable for at least 2 months).

Production platform:
HEK293 cells using the rPEx™ recombinant protein production platform.

Datasheet URL:
https://products.ipatherapeutics.com/product/c005/

Storage temp.	-80°C	Manufacturer	ImmunoPrecise Antibodies (Europe) BV
Alternative names	cytotoxic T-lymphocyte protein 4 isoform, CTLA4-TM, cytotoxic T-lymphocyte-associated serine esterase-4, cytotoxic T-lymphocyte-associated antigen 4, cytotoxic T-lymphocyte protein 4, ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4, cytotoxic T-lymphocyte antigen 4, CD152 isoform, cytotoxic T lymphocyte associated antigen 4 short spliced form
Background	Product description: CTLA4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. Residues 36-162 of human CTLA4, containing the extracellular domain - ECD -, were cloned, the protein was over-expressed in HEK293 cells and was purified to homogeneity. The calculated molecular weight of recombinant human CD40-ECD is 14.9 kDa and it contains an C-terminal hexahistidine tag. Reference sequences: Swiss-prot P16410
Product category	Research area Immunology Cell surface antigens

The availability is based on the information in Japan at 17:00, Feb 17, 2025 in JST.
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For storage temparature: RT: room temparature
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