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HOME > Product search results > Code No. QK006-0025 recombinant human R-spondin 1 protein

Code No. QK006-0025

recombinant human R-spondin 1 protein

Price

¥35,000

Availability (in Japan)

10 or more

(In Japan at 00:05,
Apr 20, 2024 in JST)

Size

25 µg

Qk006 is animal-free and not glycosylated to ensure production of homogeneous protein and enhanced comparability between batches. Used to replace R-spondin conditioned media for improved reproducibility in chemically defined organoid culture media.13kDa highly pure, bioactive domain of human R-spondin 1 comprising the two cysteine-rich furin-like domains of R-spondin 1, which are necessary and sufficient for Wnt signalling potentiation and are the essential domains for activity in stem cell and organoid culture.

datasheet url: https://qkine.com/product/recombinant-human-rspondin-1-protein/
source: E.coli expressed
molecular weight: 13 kDa (A biologically active fragment comprising of two cysteine-rich, furin-like domains)
form: lyophilized
Intended use stem cell culture; organoid culture
Storage temp. -20°C Manufacturer Qkine Ltd
Alternative names roof plate-specific spondin 1, Rspo1, R-spondin 1, Cristin 3
Background To enhance reproducibility and support scale-up, all Qkine's growth factors and cytokines are:
■ High purity and bioactive
■ Carrier protein free
■ Animal-origin free (AOF) or animal-derived component free (ADCF)

Human R-spondin 1 protein (RSP1) is the prototypic member of the R-spondin family and is used to potentiate Wnt signalling in many organoid culture systems including intestinal and tumor (cancer) organoid culture. R-spondin 1 is also required for hematopoietic stem cell specification and cancer cell migration and survival.13kDa highly pure, bioactive domain of human R-spondin 1 comprising the two cysteine-rich furin-like domains of R-spondin 1, which are necessary and sufficient for Wnt signalling potentiation and are the essential domains for activity in stem cell and organoid culture.
Notes When culturing organoids, stem cells, or other tissues, if you are to use this product in combination with other factor or factors (hereunder factors), a third party may have a patent on the use or other application of the factors concerned.Regarding to this product, we do not offer any non-infringement warranty when used or otherwise applied in combination with other factors. Therefore, if you intend to use this product in combination with other factors, please check with your organization’s division responsible for intellectual property rights or your research agency before using this product.
Product category
Research area
Stem cell research
Cytokine & Growth Factors
Organoid
Tools
Cell culture reagents
Brands
Qkine
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