Clear Back (Human Fc receptor blocking reagent)

Price

¥16,500

Availability (in Japan)

10 or more

（In Japan at 17:00,
Dec 13, 2024 in JST）

Size

1 mL (50 tests)x2

Citations

Data Sheet

SDS

This reagent can block non-specific bindings of antibodies to cells caused by human FcR for such experiments as FCM, Fluorescent microscopy, etc. Normal goat IgG in this reagent can also block non-specific bindings caused by any goat secondary antibodies. In an experiment of staining cells with T-Select MHC Tetramer, Clear Back may block non-specific bindings caused by macrophages or endocytosis, resulting in clear staining.

Storage temp.	冷蔵	Manufacturer	MBL
Citations	Kobayashi M et al. The feasibility and clinical effects of dendritic cell-based immunotherapy targeting synthesized peptides for recurrent ovarian cancer. J Ovarian Res. 7, 48 (2014)(PMID:25298213) Honda T et al. Novel designs of single-chain MHC I/peptide complex for the magnetosome display system. Protein Eng Des Sel. 28, 53-8 (2015)(PMID:25573535) Miyashita T et al. Low-dose valproic acid with low-dose gemcitabine augments MHC class I-related chain A/B expression without inducing the release of soluble MHC class I-related chain A/B. Oncol Lett. 14, 5918-5926 (2017)(PMID:29113227) Otsuki N Et al. A new biomarker candidate for spinal muscular atrophy: Identification of a peripheral blood cell population capable of monitoring the level of survival motor neuron protein. PLoS One. 13, e0201764 (2018)(PMID:30102724) Tsuboi A et al. A phase I clinical study of a cocktail vaccine of Wilms' tumor 1 (WT1) HLA class I and II peptides for recurrent malignant glioma. Cancer Immunol Immunother. 68, 331-340 (2019)(PMID:30430205) Yawata T et al. CD146 is highly expressed in glioma stem cells and acts as a cell cycle regulator. J Neurooncol. 144, 21-32 (2019)(PMID:31147892) Yamashita Y et al. CD4⁺ T Responses Other Than Th1 Type Are Preferentially Induced by Latency-Associated Antigens in the State of Latent Mycobacterium tuberculosis Infection. Front Immunol. 10, 2807 (2019) (PMID:31849981)
Product category	Tools Flow cytometry reagents

Storage temp.

冷蔵

Manufacturer

MBL

Citations

Kobayashi M et al. The feasibility and clinical effects of dendritic cell-based immunotherapy targeting synthesized peptides for recurrent ovarian cancer. J Ovarian Res. 7, 48 (2014)(PMID:25298213)

Honda T et al. Novel designs of single-chain MHC I/peptide complex for the magnetosome display system. Protein Eng Des Sel. 28, 53-8 (2015)(PMID:25573535)

Miyashita T et al. Low-dose valproic acid with low-dose gemcitabine augments MHC class I-related chain A/B expression without inducing the release of soluble MHC class I-related chain A/B. Oncol Lett. 14, 5918-5926 (2017)(PMID:29113227)

Otsuki N Et al. A new biomarker candidate for spinal muscular atrophy: Identification of a peripheral blood cell population capable of monitoring the level of survival motor neuron protein. PLoS One. 13, e0201764 (2018)(PMID:30102724)

Tsuboi A et al. A phase I clinical study of a cocktail vaccine of Wilms' tumor 1 (WT1) HLA class I and II peptides for recurrent malignant glioma. Cancer Immunol Immunother. 68, 331-340 (2019)(PMID:30430205)

Yawata T et al. CD146 is highly expressed in glioma stem cells and acts as a cell cycle regulator. J Neurooncol. 144, 21-32 (2019)(PMID:31147892)

Yamashita Y et al. CD4⁺ T Responses Other Than Th1 Type Are Preferentially Induced by Latency-Associated Antigens in the State of Latent Mycobacterium tuberculosis Infection. Front Immunol. 10, 2807 (2019) (PMID:31849981)

Product category

Tools: Flow cytometry reagents

The availability is based on the information in Japan at 17:00, Dec 13, 2024 in JST.
The special price is shown in red color.
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For storage temparature: RT: room temparature
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