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HOME > Product search results > Code No. CY-8078 CircuLex Mouse/Rat PCSK9 ELISA Kit

Code No. CY-8078

CircuLex Mouse/Rat PCSK9 ELISA Kit



Availability (in Japan)


(In Japan at 17:00,
Sep 24, 2021 in JST)


96 assays


  • Concentrations of mouse PCSK9 in Balb/c mice serum. (n = 20)

Components Microplate, Wash Buffer, Dilution Buffer, Mouse PCSK9 Standard, HRP conjugated Detection Antibody, Substrate Reagent, Stop Solution
Intended use This Kit is used for the quantitative measurement of Mouse and Rat PCSK9 in serum, plasma, cell culture medium and other biological media.
Storage temp. 4°C Manufacturer MBL
Sample Serum
Measurement range 0.094~6 ng/mL
Sensitivity 38.1 pg/mL~
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  1. Carrier B et al. Alpha-lipoic acid reduces LDL-particle number and PCSK9 concentrations in high-fat fed obese Zucker rats. PLoS One. 9, e90863 (2014)(PMID:24595397)
  1. Sasaki M et al. Hepatic overexpression of idol increases circulating protein convertase subtilisin/kexin type 9 in mice and hamsters via dual mechanisms: sterol regulatory element-binding protein 2 and low-density lipoprotein receptor-dependent pathways. Arterioscler Thromb Vasc Biol. 34, 1171-8 (2014)(PMID:24675665)
  1. Galabova G et al. Peptide-based anti-PCSK9 vaccines - an approach for long-term LDLc management. PLoS One. 9, e114469 (2014)(PMID:25474576)
  1. Berger JM et al. PCSK9-deficiency does not alter blood pressure and sodium balance in mouse models of hypertension. Atherosclerosis 239, 252-9 (2015)(PMID:25621930)
  1. Butkinaree C et al. Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other. J Biol Chem. 290, 18609-20 (2015)(PMID:26085104)
  1. An D et al. Identification of PCSK9 as a novel serum biomarker for the prenatal diagnosis of neural tube defects using iTRAQ quantitative proteomics. Sci Rep. 5, 17559 (2015)(PMID:26691006)
  1. Haas ME et al. The Role of Proprotein Convertase Subtilisin/Kexin Type 9 in Nephrotic Syndrome-Associated Hypercholesterolemia. Circulation 134, 61-72 (2016)(PMID:27358438)
  1. Ngo  Sock ET et al. Combined Effects of Rosuvastatin and Exercise on Gene Expression of Key Molecules Involved in Cholesterol Metabolism in Ovariectomized Rats. PLoS One. 11, e0159550 (2016)(PMID:27442011)
  1. Lintner NG et al. Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain. PLoS Biol. 15, e2001882 (2017)(PMID:28323820)
  1. Xu YX et al. Role of angiopoietin-like 3 (ANGPTL3) in regulating plasma level of low-density lipoprotein cholesterol. Atherosclerosis 268, 196-206 (2018)(PMID:29183623)
  1. Yang SH et al. Liraglutide downregulates hepatic LDL receptor and PCSK9 expression in HepG2 cells and db/db mice through a HNF-1a dependent mechanism. Cardiovasc Diabetol. 17, 48 (2018)(PMID:29618348)
  1. Ding Z et al. PCSK9 expression in the ischemic heart and its relationship to infarct size, cardiac function and development of autophagy. Cardiovasc Res. (2018) In press.(PMID:29800228)
  1. Liu Y et al. PCSK9 positively correlates with plasma sdLDL in community-dwelling population but not in diabetic participants after confounder adjustment. Medicine (Baltimore). 98, e15062 (2019)(PMID:30946354)
  1. Momtazi-Borojeni AA et al. Potential anti-tumor effect of a nanoliposomal antiPCSK9 vaccine in mice bearing colorectal cancer. Arch Med Sci. 15, 559-569 (2019) (PMID:31110520)
  1. Momtazi-Borojeni AA et al. Effects of immunization against PCSK9 in an experimental model of breast cancer. Arch Med Sci. 15, 570-579 (2019) (PMID:31110521)
  1. Momtazi-Borojeni AA et al. Therapeutic Effect of Nanoliposomal PCSK9 Vaccine in a Mouse Model of Atherosclerosis. BMC Med. 17, 223 (2019) (PMID:31818299)
  1. Momtazi-Borojeni AA et al. Effects of Immunisation Against PCSK9 in Mice Bearing Melanoma. Arch Med Sci. 16, 189-199 (2019)(PMID:32051723)
  1. Low LD et al. IL-13-driven Alterations in Hepatic Cholesterol Handling Contributes to Hypercholesterolemia in a Rat Model of Minimal Change Disease. Clin Sci (Lond). 134, 225-237 (2020)(PMID:31934720)
  1. Evison BJ et al. A Small Molecule Inhibitor of PCSK9 That Antagonizes LDL Receptor Binding via Interaction With a Cryptic PCSK9 Binding Groove. Bioorg Med Chem. 28, 115344 (2020)(PMID:32051094)
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  1. Ding Z et al. NLRP3 inflammasome via IL-1β regulates PCSK9 secretion. Theranostics. 10, 7100-7110 (2020)(PMID:32641981)
Product category
Research area
Drug discovery

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