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HOME > Product search results > Code No. CY-8058V2 CircuLex S100A12/EN-RAGE ELISA Kit Ver.2

Code No. CY-8058V2

CircuLex S100A12/EN-RAGE ELISA Kit Ver.2

Price

¥98,000

Availability (in Japan)

10 or more

(In Japan at 17:00,
Nov 14, 2019 in JST)

Size

96 Assay

Data
  • Example of Test Results

    Example of Test Results
    Human S100A12 concentration insera from Crohn's disease patients (n=10) and healthy volunteers (n=8).

Components Microplate, 10X Wash Buffer, Dilution Buffer, Human S100A12 Standard, HRP conjugated Detection Antibody, Substrate Reagent, Stop Solution
Intended use This Kit is used for the quantitative measurement of human S100A12/EN-RAGE in serum, plasma, and other biological media.
Storage temp. 4°C Manufacturer MBL
Sample Serum, Plasma, Other biological media
Measurement range 20 - 1,280 pg/mL
Sensitivity 8.2 pg/mL~
Alternative names CAGC, CGRP, MRP-6, CAAF1
Citations
  1. Kikkawa T et al. Significance of measuring S100A12 and sRAGE in the serum of sepsis patients with postoperative acute lung injury. Dig Surg. 27, 307-312 (2010)(PMID:20689292)
  1. Smith DJ et al. Reduced soluble receptor for advanced glycation end products in chronic obstructive pulmonary disease. Eur Respir J. 37, 516-22 (2011)(PMID:20595148)
  1. Nakashima A et al. Effect of Circulating Soluble Receptor for Advanced Glycation End Products (sRAGE) and the Proinflammatory RAGE Ligand (EN-RAGE, S100A12) on Mortality in Hemodialysis Patients. Clin J Am Soc Nephrol. 5, 2213-9 (2010)(PMID:20847094)
  1. Andrés Cerezo L et al.Decreases in serum levels of S100A8/9 (calprotectin) correlate with improvements in total swollen joint count in patients with new-onset rheumatoid arthritis. Arthritis Res Ther. 13, R122 (2011)(PMID:21791097)
  1. Takahashi G et al.Retrospective study on the effect of tight glucose control in postoperative sepsis patients using an artificial pancreas. J Infect Chemother.17, 812-20 (2011)(PMID:21681499)
  1. Kim JK et al. Plasma levels of soluble receptor for advanced glycation end products (sRAGE) and proinflammatory ligand for RAGE (EN-RAGE) are associated with carotid atherosclerosis in patients with peritoneal dialysis. Atherosclerosis 220, 208-14 (2012)(PMID:21906738)
  1. Han EC et al. Expression of Pro-inflammatory Protein S100A12 (EN-RAGE) in Beh_et's Disease and Its Association with Disease Activity: A Pilot Study. Ann Dermatol. 23, 313-20 (2011)(PMID:21909201)
  1. Takahashi G et al. Changes in Serum S100A12 and sRAGE Associated with Improvement of the PaO(2)/FiO(2) Ratio following PMX-DHP Therapy for Postoperative Septic Shock. Eur Surg Res. 47, 135-140 (2011)(PMID:21921634)
  1. Liu K et al. Transcriptome signature in young children with acute otitis media due to Streptococcus pneumoniae. Microbes Infect. 14, 600-9 (2012)(PMID:22306269)
  1. Yamamoto T et al. Changes in circulating biomarkers during a single hemodialysis session. Hemodial Int. 17, 59-66 (2013)(PMID:22716238)
  1. Silajd?i? E et al. A critical evaluation of inflammatory markers in Huntington's Disease plasma. J Huntingtons Dis. 2, 125-34 (2013)(PMID:25063434)
  1. Peiskerová M et al. Placental growth factor may predict increased left ventricular mass index in patients with mild to moderate chronic kidney disease--a prospective observational study. BMC Nephrol. 14, 142 (2013)(PMID:23844967)
  1. Tydén H et al. Increased serum levels of S100A8/A9 and S100A12 are associated with cardiovascular disease in patients with inactive systemic lupus erythematosus. Rheumatology Rheumatology 52, 2048-55 (2013)(PMID:23942785)
  1. Kim HS et al. Circulating levels of soluble receptor for advanced glycation end product are inversely associated with vascular calcification in patients on haemodialysis independent of S100A12 (EN-RAGE) levels. Nephrology 18, :777-82 (2013)(PMID:24124651)
  1. Zakiyanov O et al. Placental growth factor, pregnancy-associated plasma protein-A, soluble receptor for advanced glycation end products, extracellular newly identified receptor for receptor for advanced glycation end products binding protein and high mobility group box 1 levels in patients with acute kidney injury: a cross sectional study. BMC Nephrol. 14, 245 (2013)(PMID:24188108)
  1. Rothmund F et al. Validation of relapse risk biomarkers for routine use in patients with juvenile idiopathic arthritis. Arthritis Care Res. 66, 949-55 (2014)(PMID:24339418)
  1. Hara M et al. S100A12 gene expression is increased in peripheral leukocytes in chronic kidney disease stage 4-5 patients with cardiovascular disease. Nephron Clin Pract. 123, 202-8 (2013)(PMID:23921255)
  1. Sundqvist M et al. Increased intracellular oxygen radical production in neutrophils during febrile episodes of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome. Arthritis Rheum. 65, 2971-83 (2013)(PMID:23983059)
  1. Glasnovic A et al. Decreased level of sRAGE in the cerebrospinal fluid of multiple sclerosis patients at clinical onset. Neuroimmunomodulation. 21, 226-33 (2014)(PMID:24603633)
  1. Farkas G Jr et al. Analysis of plasma levels and polymorphisms of S100A8/9 and S100A12 in patients with acute pancreatitis. Pancreas. 43, 485-7 (2014)(PMID:24622086)
  1. Kim JK, Park S, Lee MJ, Song YR, Han SH, Kim SG, Kang SW, Choi KH, Kim HJ, Yoo TH.; Plasma levels of soluble receptor for advanced glycation end products (sRAGE) and proinflammatory ligand for RAGE (EN-RAGE) are associated with carotid atherosclerosis in patients with peritoneal dialysis. Atherosclerosis. 220:208-14. 2012(PMID:21906738)
  1. Han EC, Cho SB, Ahn KJ, Oh SH, Kim J, Kim DS, Lee KH, Bang D.; Expression of Pro-inflammatory Protein S100A12 (EN-RAGE) in Beh_et's Disease and Its Association with Disease Activity: A Pilot Study. Ann Dermatol. 23: 313-20. 2011(PMID:21909201)
  1. Takahashi G, Hoshikawa K, Matsumoto N, Shozushima T, Onodera C, Kan S, Akitomi S, Kikkawa T, Tomisawa Y, Kojika M, Sato N, Inoue Y, Suzuki K, Wakabayashi G, Endo S.; Changes in Serum S100A12 and sRAGE Associated with Improvement of the PaO(2)/FiO(2) Ratio following PMX-DHP Therapy for Postoperative Septic Shock. Eur Surg Res. 47(3):135-140. 2011(PMID:21921634)
  1. Liu K, Chen L, Kaur R, Pichichero M.; Transcriptome signature in young children with acute otitis media due to Streptococcus pneumoniae. Microbes Infect. 14: 600-9. 2012(PMID:22306269)
  1. Saito T et al. Distinct expression patterns of alveolar "alarmins" in subtypes of chronic lung allograft dysfunction. Am J Transplant. 14, 1425-32 (2014)(PMID:24787265)
  1. Fukasawa H et al. Plasma levels of the pro-inflammatory protein S100A12 (EN-RAGE) are associated with muscle and fat mass in hemodialysis patients: a cross-sectional study. Nutr J. 13, 48 (2014)(PMID:24884769)
  1. Opatrna S et al. Low glucose degradation product peritoneal dialysis regimen is associated with lower plasma EN-RAGE and HMGB-1 proinflammatory ligands of receptor for advanced glycation end products. Ther Apher Dial. 18, 309-16 (2014)(PMID:24965297)
  1. Isoyama N et al. Plasma S100A12 and soluble receptor of advanced glycation end product levels and mortality in chronic kidney disease Stage 5 patients. Nephrol Dial Transplant. 30, 84-91 (2014)(PMID:25074436)
  1. Bae CB et al. Serum S100A12 may be a useful biomarker of disease activity in adult-onset Still's disease. J Rheumatol. 41, 2403-8 (2014)(PMID:25274901)
  1. Ma D et al. S100A12 expression in patients with primary biliary cirrhosis. Immunol Invest. 44, 13-22 (2014)(PMID:25313445)
  1. He YY et al. Usefulness of S100A12 as a prognostic biomarker for adverse events in patients with heart failure. Clin Biochem. 48, 329-33 (2015)(PMID:25438075)
  1. Turnier JL et al. Urine S100 proteins as potential biomarkers of lupus nephritis activity. Arthritis Res Ther. 19, 242
    (2017)(PMID:29065913)
  1. Šumová B et al. Circulating S100 proteins effectively discriminate SLE patients from healthy controls: a cross-sectional study. Rheumatol Int. 39, 469-478 (2019)(PMID:30392117)
  1. Yamasaki Y et al. S100A12 and vascular endothelial growth factor can differentiate Blau syndrome and familial Mediterranean fever from systemic juvenile idiopathic arthritis. Clin Rheumatol. 38, 835-840 (2019)(PMID:30406853)
  1. Nikolakopoulou Z et al. Plasma S100A8/A9 heterodimer is an early prognostic marker of acute kidney injury associated with cardiac surgery. Biomark Med. 13, 205-218 (2019)(PMID:30810341)
Product category
Research area
Immunology
Metabolism
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