Code No. | W357-3 | |
Anti-CD105 (Endoglin) (Human) mAb | ||
Price | ¥52,800 | |
Size | 100 µL (1 mg/mL) | |
Availability (in Japan) | 10 or more
(In Japan at 17:00, Feb 11, 2025 in JST) |
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Clonality | Monoclonal | |
Clone | 3G4A6 | |
Isotype (Immunized Animal) |
Mouse IgG2bκ | |
Applications | FCM 1-10 µg/mL |
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Immunogen (Antigen) |
Human CD105 (Endoglin) expressed Ba/F3 transfectants generated from SST-REX (signal sequence trap by retrovirus-mediated expression screening). | |
Reactivity [Gene ID] | Human[2022] |
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Storage buffer | 1 mg/mL in PBS/50% glycerol, pH 7.2 | |
Storage temp. | -20°C | |
Conjugate | Unlabeled | |
Manufacturer | MBL | |
Alternative names | END, HHT1, ORW1 | |
Background | Endoglin, also known as CD105, is a type I membrane protein. Endoglin is a major glycoprotein located on the cell surface of vascular endothelium. It is involved in regulation of angiogenesis. In cancer tissue, endoglin is over-expressed in proliferating endothelial cells which line tumor blood vessels. Moreover, tumor cells also express endoglin in prostate cancer and melanoma. Endoglin might be a good candidate to be used for tumor imaging and for targeted cancer therapy. | |
Related products | W164-3 Anti-RHBDD3 (Human) mAb M077-3 Mouse IgG2b (isotype control) MTG-001 Clear Back (Human Fc receptor blocking reagent) |
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Product category | Research area:Cancer Tools:Flow cytometry reagents |
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Data | ![]() |
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References |
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