Antibody detailed product information
| Code No. | RN030PW | |
| Anti-DICER1 (Human) pAb | ||
| Price | ¥52,800 | |
| Size | 100 µL (1 mg/mL) | |
| Availability (in Japan) | 10 or more
（In Japan at 17:00, Apr 24, 2024 in JST） |
|
| Clonality | Polyclonal | |
| Clone | Polyclonal | |
| Isotype (Immunized Animal) |
Rabbit Ig (aff.) | |
| Applications | WB 1:1,000 IP 5 µL/500 µL of cell extract from 5 x 106 cells |
|
| Immunogen (Antigen) |
KLH conjugated synthetic peptide, corresponding to internal region of human DICER1 | |
| Reactivity [Gene ID] | Human[23405], Mouse(-), Rat(-) |
|
| Storage buffer | 1 mg/mL in PBS/50% glycerol, pH 7.2 | |
| Storage temp. | -20°C | |
| Conjugate | Unlabeled | |
| Manufacturer | MBL | |
| Alternative names | dicer 1, ribonuclease type III, DCR1, MNG1, Dicer | |
| Background | Dicer1 is an endonuclease of the ribonuclease III (RNase III) family. It contains a DExH RNA helicase/ATPase domain, a Piwi/Argonaute/Zwille domain, a domain of unknown function, two RNase III domains, and a double-stranded RNA (dsRNA) binding domain. Dicer1 processes dsRNAs and pre-microRNAs into short RNA fragments of about 21–25 nucleotides in length. It is an initiating factor of the RNA interference pathway and plays a role in microRNA biogenesis and function. Dicer also mediates DNA hypermethylation and gene silencing in human colon cancer cell line. | |
| Related products | RN003M Anti-EIF2C2 (AGO2) (Human) mAb RN058PW Anti-TARBP2 pAb RN1001 RIP-Assay Kit RN1005 RIP-Assay Kit for microRNA |
|
| Product category | Research area:RNA-RNP Network Brands:RiboCluster Profiler™ |
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| Data |   |
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- The availability is based on the information in Japan at 17:00, Apr 24, 2024 in JST.
- The special price is shown in red color.
- Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
- Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization - For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
- For storage temparature: RT: room temparature
- Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.
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