Antibody detailed product information

Code No. RN019P
Anti-HNRNPK pAb
Price ¥69,300
Size 200 µL (1 mg/mL)
Availability (in Japan) 1-9
（In Japan at 00:05, Apr 12, 2026 in JST）
Clonality Polyclonal
Clone Polyclonal
Isotype
(Immunized Animal) 		Rabbit Ig (aff.)
Applications WB　1 µg/mL  
IP　5 µg/500 µL of cell extract from 5 x 106 cells  
IC*　reported.  （PMID: 24990929 / 26990993）
RIP　15 µg/500 µL of cell extract from 1.5 x 107 cells  
Other(eCLIP)　reported.  （PMID: 27018577）
Immunogen
(Antigen)		 "KLH conjugated synthetic peptide, corresponding to C-terminus of human HNRNPK"
Reactivity [Gene ID]

Human[3190], Mouse[15387], Rat[117282]
Storage buffer "1 mg/mL in PBS/50% glycerol, pH 7.2"
Storage temp. -20°C
Conjugate Unlabeled
Manufacturer MBL
Alternative names "heterogeneous nuclear ribonucleoprotein K, RP11-575L7.1, CSBP, HNRPK, TUNP"
Background "The heterogeneous nuclear ribonucleoprotein K (hnRNP K), is an RNA-binding protein containing 3 KH RNA-binding domains. It binds to both RNA and DNA and is a component of the hnRNP complex. hnRNP K is associated with pre-mRNA and appears to influence the processing of pre-mRNAs and metabolism of mRNA. hnRNP K is predominantly localized at the nucleus and shuttles between the nucleus and the cytoplasm. Therefore, hnRNP K is thought to be involved in the transport of mRNA. Phosphorylation of hnRNP K leads to its cytoplasmic accumulation and is important for cell migration and metastasis. In the cytoplasm, hnRNP K functions as a translational regulator of specific mRNAs such as c-myc mRNA, 16L2 mRNA, and r15-LOX mRNA. Further, it specifically associates with c-src kinase, leading to c-src activation and hnRNP K phosphorylation, which affect the binding of hnRNP K to RNA."
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Product category Research area:RNA-RNP Network
Brands:RiboCluster Profiler™
Data



Citations

Western Blotting

  1. Folci A et al. Loss of hnRNP K impairs synaptic plasticity in hippocampal neurons. J Neurosci. 34, 9088-95 (2014)(PMID:24990929)
  2. Chung BM et al. Regulation of C-X-C chemokine gene expression by keratin 17 and hnRNP K in skin tumor keratinocytes.　J Cell Biol. 208, 613-27 (2015)(PMID:25713416)

Immunoprecipitation

  1. Chung BM et al. Regulation of C-X-C chemokine gene expression by keratin 17 and hnRNP K in skin tumor keratinocytes.　J Cell Biol. 208, 613-27 (2015)(PMID:25713416)

Immunocytochemistry

  1. Folci A et al. Loss of hnRNP K impairs synaptic plasticity in hippocampal neurons. J Neurosci. 34, 9088-95 (2014)(PMID:24990929)
  2. Chung BM et al. Regulation of C-X-C chemokine gene expression by keratin 17 and hnRNP K in skin tumor keratinocytes.　J Cell Biol. 208, 613-27 (2015)(PMID:25713416)
  3. Sundararaman B et al. Resources for the Comprehensive Discovery of Functional RNA Elements. Mol Cell. 61, 903-13 (2016)(PMID:26990993)

RNP Immunoprecipitation

  1. Chung BM et al. Regulation of C-X-C chemokine gene expression by keratin 17 and hnRNP K in skin tumor keratinocytes.　J Cell Biol. 208, 613-27 (2015)(PMID:25713416)
  2. Lubelsky Y, Ulitsky I. Sequences enriched in Alu repeats drive nuclear localization of long RNAs in human cells. Nature 555, 107-111 (2018)(PMID:29466324)

Other(eCLIP)

  1. Van Nostrand EL et al. Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP). Nat Methods. 13, 508-14 (2016)(PMID:27018577)
  • The availability is based on the information in Japan at 00:05, Apr 12, 2026 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications：
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.
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