Antibody detailed product information

Code No. PM059 プリントPrint out
Anti-KDEL pAb
Price ¥25,000
Size 100 µL
Availability (in Japan) 1-9
(In Japan at 17:00, Feb 23, 2020 in JST)
Clonality Polyclonal
Clone Polyclonal
Isotype
(Immunized Animal)
Rabbit Ig (aff.)
Applications WB 1:500  
IC 1:1,000  
IH* reported.  (PMID: 19767744)
IF* reported.  (PMID: 28342860)
Immunogen
(Antigen)
Mouse GRP78 C-terminal 644-654 aa
Reactivity [Gene ID]

Human, Mouse

Storage buffer PBS/50% glycerol, pH 7.2
Storage temp. -20°C
Conjugate Unlabeled
Manufacturer MBL
Background The KDEL (lys-asp-glu-leu) sequence is most common endoplasmic reticulum (ER) retention signal. The ER resident proteins, which should be located in the ER, have this retention motif, and this retention is mediated by KDEL receptor. This antibody can specifically detect GRP78 (78 kDa protein) and GRP94 (94 kDa protein) including a KDEL sequence by WB.
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Product category Tools:Control antibodies Others
Data


Citations

Immunocytochemistry

  1. Ishii S et al. Functional characterization of lysophosphatidic acid receptor 1 mutants identified in rat cancer tissues. Biochem Biophys Res Commun. 486, 767-773 (2017)(PMID:28342860)
  2. Kouga T et al. Drug screening for Pelizaeus-Merzbacher disease by quantifying the total levels and membrane localization of PLP1. Mol Genet Metab Rep. 20, 100474 (2019)(PMID:31110947)

Immunohistochemistry

  1. Saito A et al. Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis. Nat Cell Biol. 11, 1197-1204 (2009)(PMID:19767744)
  2. Yamanaka T et al. NF-Y inactivation causes atypical neurodegeneration characterized by ubiquitin and p62 accumulation and endoplasmic reticulum disorganization. Nat Commun. 5, 3354 (2014)(PMID:24566496)
  3. Yamanaka T et al. Differential roles of NF-Y transcription factor in ER chaperone expression and neuronal maintenance in the CNS. Sci Rep. 6, 34575 (2016)(PMID:27687130)
  • The availability is based on the information in Japan at 17:00, Feb 23, 2020 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.
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