Code No. |
PM050 |
Anti-Atg5 pAb
|
Price |
¥41,800
|
Size |
100 µL |
Availability (in Japan) |
1-9
(In Japan at 00:05, Apr 19, 2024 in JST)
|
Clonality |
Polyclonal |
Clone |
Polyclonal |
Isotype
(Immunized Animal) |
Rabbit Ig (aff.) |
Applications |
WB 1:500
|
Immunogen
(Antigen) |
synthetic peptide corresponding to C-terminus of human Atg5 |
Reactivity [Gene ID] |
Human[9474], Mouse[11793], Rat[365601], Hamster(-) |
Storage buffer |
PBS/50% glycerol, pH 7.2 |
Storage temp. |
-20°C |
Conjugate |
Unlabeled |
Manufacturer |
MBL |
Alternative names |
autophagy related 5, ASP, APG5, APG5L, hAPG5, APG5-LIKE |
Related products |
8485 Autophagy Ab Sampler Set M153-3 Anti-Atg5 mAb M133-3 Anti-Atg3 mAb PM039 Anti-Atg7 (Human) pAb PM036 Anti-LC3 pAb M152-3 Anti-LC3 mAb PD042 Anti-Atg9A pAb M154-3 Anti-Atg12 (Human) mAb PM040 Anti-Atg16L pAb M150-3 Anti-Atg16L mAb M151-3 Anti-Atg10 (Human) mAb PM072 Anti-VMP1 pAb PD017 Anti-Beclin 1 pAb
|
Notes |
This antibdy detects Atg5-Atg12 complex (55 kDa). |
Product category |
Research area:Autophagy |
Data |
|
Citations |
Western Blotting - Ni HM et al. Dissecting the dynamic turnover of GFP-LC3 in the autolysosome. Autophagy 7, 188-204 (2011)(PMID:21107021)
- Myeku N, Figueiredo-Pereira ME. Dynamics of the degradation of ubiquitinated proteins by proteasomes and autophagy: association with sequestosome 1/p62. J Biol Chem. 286, 22426-40 (2011)(PMID:21536669)
- Ni HM et al. Critical role of FoxO3a in alcohol-induced autophagy and hepatotoxicity. Am J Pathol. 183, 1815-25 (2013)(PMID:24095927)
- Maejima Y et al. Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2. Nat Med. 19, 1478-88 (2013)(PMID:24141421)
- Manley S et al. Suppression of autophagic flux by bile acids in hepatocytes. Toxicol Sci. 137, 478-90 (2014)(PMID:24189133)
- Liu ML et al. Tri-ortho-cresyl phosphate induces autophagy of rat spermatogonial stem cells. Reproduction 149, 163-70 (2015)(PMID:25385720)
- Xu D et al. Modification of BECN1 by ISG15 plays a crucial role in autophagy regulation by type I IFN/interferon. Autophagy 11, 617-28 (2015)(PMID:25906440)
- Matsuzawa Y et al.TNFAIP3 promotes survival of CD4 T cells by restricting MTOR and promoting autophagy. Autophagy 11, 1052-62 (2015)(PMID:26043155)
- Unuma K et al. Extrusion of mitochondrial contents from lipopolysaccharide-stimulated cells: Involvement of autophagy. Autophagy 11, 1520-36 (2015)(PMID:26102061)
- Liu X et al. Involvement of oxidative stress in tri-ortho-cresyl phosphate-induced autophagy of mouse Leydig TM3 cells in vitro. Reprod Biol Endocrinol. 14, 30 (2016)(PMID:27267904)
- Yamashita SI et al. Mitochondrial division occurs concurrently with autophagosome formation but independently of Drp1 during mitophagy. J Cell Biol. 215, 649-665 (2016)(PMID:27903607)
- Asano J et al. Intrinsic Autophagy Is Required for the Maintenance of Intestinal Stem Cells and for Irradiation-Induced Intestinal Regeneration. Cell Rep. 20, 1050-1060 (2017)(PMID:28768191)
- Fujiwara M et al. Decreased grip strength, muscle pain, and atrophy occur in rats following long-term exposure to excessive repetitive motion. FEBS Open Bio. 7, 1737-1749 (2016)(PMID:29123982)
- Li Y et al. Impaired Fasting-Induced Adaptive Lipid Droplet Biogenesis in Liver-Specific Atg5-Deficient Mouse Liver Is Mediated by Persistent Nuclear Factor-Like 2 Activation. Am J Pathol. 188, 1833-1846 (2018)(PMID:29803835)
- Araki K et al. Mitochondrial protein E2F3d, a distinctive E2F3 product, mediates hypoxia-induced mitophagy in cancer cells. Commun Biol. 2, 3 (2019)(PMID:30740539)
- Saladini S et al. Metformin Impairs Glutamine Metabolism and Autophagy in Tumour Cells. Cells. 8, pii: E49 (2019)(PMID:30646605)
- Shen J et al. Role of Autophagy in Zinc Oxide Nanoparticles-Induced Apoptosis of Mouse LEYDIG Cells. Int J Mol Sci. 20, pii: E4042 (2019)(PMID:31430870)
- Ye X et al. Lipopolysaccharide Induces Neuroinflammation in Microglia by Activating the MTOR Pathway and Downregulating Vps34 to Inhibit Autophagosome Formation. J Neuroinflammation. 17, 18 (2020)(PMID:31926553)
- Manirujjaman M et al. Degradation of the Tumor Suppressor PDCD4 Is Impaired by the Suppression of p62/SQSTM1 and Autophagy. Cells. 9, 218 (2020)(PMID:31952347)
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