Antibody detailed product information

Code No.	PM014
Anti-IL-18 (Human) pAb
Price	¥52,800
Size	100 µL
Availability (in Japan)	10 or more （In Japan at 00:05, Apr 24, 2024 in JST）
Clonality	Polyclonal
Clone	Polyclonal
Isotype (Immunized Animal)	Rabbit IgG
Applications	WB　1:1,000 IH　1:200 (Heat treatment is necessary for paraffin embedded sections.)
Immunogen (Antigen)	Recombinant Human IL-18
Reactivity [Gene ID]	Human[3606], Mouse(-)
Storage buffer	PBS/50% glycerol, pH 7.2
Storage temp.	-20°C
Conjugate	Unlabeled
Manufacturer	MBL
Related products	D043-3 Anti-IL-18 (Human) mAb D044-3 Anti-IL-18 (Human) mAb D045-3 Anti-IL-18 (Human) mAb D046-3 Anti-IL-18 (Mouse) mAb D047-3 Anti-IL-18 (Mouse) mAb D048-3 Anti-IL-18 (Mouse) mAb D045-6 Anti-IL-18 (Human) mAb-Biotin D048-6 Anti-IL-18 (Mouse) mAb-Biotin 7620 Human IL-18 ELISA Kit 7625 Mouse IL-18 ELISA Kit D044-3M2 Anti-IL-18 (Human) mAb (Functional Grade)
Product category	Research area:Immunology Cytokine & Growth Factors
Data
Citations	Western Blotting Allam O et al. HIV induces production of IL-18 from intestinal epithelial cells that increases intestinal permeability and microbial translocation. PLoS One 13, e0194185 (2018)(PMID:29601578) Ashida H et al. A unique bacterial tactic to circumvent the cell death crosstalk induced by blockade of caspase-8. EMBO J. 39, e104469 (2020)(PMID:32657447) Immunohistochemistry Hirano H et al. TLR4, IL-6, IL-18, MyD88 and HMGB1 are highly expressed in intracranial inflammatory lesions and the IgG4/IgG ratio correlates with TLR4 and IL-6. Neuropathology 32, 628-37 (2012)(PMID:22414145) Komsky A et al. Presence of IL-18 in testicular tissue of fertile and infertile men. Andrologia 44, 1-8 (2012)(PMID:21615452)

The availability is based on the information in Japan at 00:05, Apr 24, 2024 in JST.
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Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
For storage temparature: RT: room temparature
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