Antibody detailed product information

Code No. PD027 プリントPrint out
Anti-Rubicon (Human) pAb
Price ¥48,000
Size 100 µL
Availability (in Japan) 10 or more
(In Japan at 00:05, Sep 17, 2021 in JST)
Clonality Polyclonal
Clone Polyclonal
Isotype
(Immunized Animal)
Rabbit Ig (aff.)
Applications WB 1:1,000  
IP 5 µL/300 µL of cell extract from 3 x 106 cells  
IH Can be used.  
Immunogen
(Antigen)
Recombinant human Rubicon, C-terminal (722-972 aa)
Reactivity [Gene ID]

Human[9711], Mouse(-)

Storage buffer PBS/50% glycerol, pH 7.2
Storage temp. -20°C
Conjugate Unlabeled
Manufacturer MBL
Alternative names KIAA0226
Background Autophagy is a process of intracellular bulk degradation in which cytoplasmic components including organelles are sequestered within double-membrane vesicles that deliver the contents to the lysosome/vacuole for degradation. Rubicon was identified as Beclin1 interacting protein. Three distinct Beclin1 complexes exist in cells, one of the complexes including Rubicon (Beclin1, hVps34, hVps15, UVRAG, Rubicon) down regulates the process of autophagosome maturation and endocytosis.
Related products M170-3 Anti-Rubicon (Human) mAb
PD017 Anti-Beclin 1 pAb
M160-3 Anti-UVRAG mAb
PD026 Anti-Atg14 pAb
M184-3 Anti-Atg14 (Human) mAb
PM072 Anti-VMP1 pAb
MD-06-3 Anti-PI3-kinase (p85α) mAb
Product category Research area:Autophagy
Data




Citations

Western Blotting

  1. Maejima Y et al. Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2. Nat Med.19, 1478-88 (2013)(PMID:24141421)
  2. Bejarano E et al. Connexins modulate autophagosome biogenesis. Nat Cell Biol. 16, 401-14 (2014)(PMID:24705551)
  • The availability is based on the information in Japan at 00:05, Sep 17, 2021 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.
MBLCopyright (C)2015 Medical & Biological Laboratories Co., Ltd. All Rights Reserve