Antibody detailed product information

Code No. PD022
Anti-Pax6 pAb
Price ¥52,800
Size 100 µL
Availability (in Japan) 10 or more
（In Japan at 00:05, Apr 19, 2024 in JST）
Clonality Polyclonal
Clone polyclonal
Isotype
(Immunized Animal) 		Rabbit Ig (aff.)
Applications WB　1:1,000  
IC*　reported.  （PMID: 26549851）
IH　Paraffin-embedded sections.; 1:200 (Heat treatment is necessary.） Cryosections; 1:1,000  
IF*　reported.  （PMID: 23056534）
Immunogen
(Antigen)		 Mouse Pax6 (C-terminal) (420-436 aa)
Reactivity [Gene ID]

Mouse[18508], Rat[25509], Chicken[395943]
Storage buffer PBS/50% glycerol, pH 7.2
Storage temp. -20°C
Conjugate Unlabeled
Manufacturer MBL
Alternative names paired box gene 6
Related products D097-3 Anti-GFAP (Glial Fibrillary Acidic Protein) mAb
D134-3 Anti-HES1 mAb
Product category Research area:Neuroscience
Data



Citations

Immunocytochemistry

  1. Imaizumi K et al. Controlling the Regional Identity of hPSC-Derived Neurons to Uncover Neuronal Subtype Specificity of Neurological Disease Phenotypes. Stem Cell Reports 5, 1010-22 (2015)(PMID:26549851)

Immunohistochemistry

  1. Ma T et al. A subpopulation of dorsal lateral/caudal ganglionic eminence-derived neocortical interneurons expresses the transcription factor Sp8. Cereb Cortex. 22, 2120-30 (2012)(PMID:22021915)
  2. Li X et al. Sp8 plays a supplementary role to Pax6 in establishing the pMN/p3 domain boundary in the spinal cord. Development 141, 2875-84 (2014)(PMID:24948600)
  3. Zhou X et al. Transcription factors COUP-TFI and COUP-TFII are required for the production of granule cells in the mouse olfactory bulb. Development 142, 1593-605 (2015)(PMID:25922524)
  4. Yamada T et al. Establishment of a recessive mutant small-rat with lens involution and retinal detachment associated with partial deletion and rearrangement of the Cryba1 gene. Biochem J. 471, 293-305 (2015)(PMID:26303524)
  5. Fujimura K et al. In Utero Exposure to Valproic Acid Induces Neocortical Dysgenesis via Dysregulation of Neural Progenitor Cell Proliferation/Differentiation. J Neurosci. 36, 10908-10919 (2016)(PMID:27798144)
  6. Ohta S et al. CHD7 promotes proliferation of neural stem cells mediated by MIF. Mol Brain 9, 96 (2016)(PMID:27955690)
  7. Hatakeyama J et al. Developing guinea pig brain as a model for cortical folding. Dev Growth Differ. 59(, 286-301 (2017)(PMID:28585227)
  8. Inoue YU et al. Generation of Pax6-IRES-EGFP knock-in mouse via the cloning-free CRISPR/Cas9 system to reliably visualize neurodevelopmental dynamics. Neurosci Res. (2018) In press.(PMID:29391173)
  9. Yamashita W et al. Conserved and divergent functions of Pax6 underlie species-specific neurogenic patterns in the developing amniote brain. Development 145, dev159764. (2018)(PMID:29661783)
  10. Farzanehfar P et al. Evidence of functional duplicity of Nestin expression in the adult mouse midbrain. Stem Cell Res. 19, 82-93 (2017)(PMID:28088038)
  11. Mitori H et al. Developing Stage-dependent Retinal Toxicity Induced by l-glutamate in Neonatal Rats. Toxicol Pathol. 44, 1137-1145 (2016)(PMID:28245157)
  12. Nakamura T et al. Novel role of Rac-Mid1 signaling in medial cerebellar development. Development 144, 1863-1875 (2017)(PMID:28512198)
  13. Arioka Y et al. Characterization of a Schizophrenia Patient With a Rare RELN Deletion by Combining Genomic and Patient-Derived Cell Analyses. Schizophr Res. 216, 511-515 (2020)(PMID:31848032)

Immunofluorescence

  1. Liu T et al. Pax6 directly down-regulates Pcsk1n expression thereby regulating PC1/3 dependent proinsulin processing. PLoS One. 7, e46934 (2012)(PMID:23056534)
  2. Maeta K et al. Crucial Role of Rapgef2 and Rapgef6, a Family of Guanine Nucleotide Exchange Factors for Rap1 Small GTPase, in Formation of Apical Surface Adherens Junctions and Neural Progenitor Development in the Mouse Cerebral Cortex. eNeuro. 3, e0142-16 (2016) 1-17(PMID:27390776)
  • The availability is based on the information in Japan at 00:05, Apr 19, 2024 in JST.
  • The special price is shown in red color.
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  • Abbreviations for applications：
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.
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