Code No. | MD-11-3 | |
Anti-Fas (CD95) (Human) mAb | ||
Price | ¥70,400 | |
Size | 100 µL (1 mg/mL) | |
Availability (in Japan) | 10 or more
(In Japan at 00:05, Feb 12, 2025 in JST) |
|
Clonality | Monoclonal | |
Clone | ZB4 | |
Isotype (Immunized Animal) |
Mouse IgG1 | |
Applications | WB 5 µg/mL FCM 5-20 µg/mL (final concentration) |
|
Immunogen (Antigen) |
Recombinant Human Fas | |
Reactivity [Gene ID] | Human[355] |
|
Storage buffer | 1 mg/mL in PBS/50% glycerol, pH 7.2 | |
Storage temp. | -20°C | |
Conjugate | Unlabeled | |
Manufacturer | MBL | |
Alternative names | Fas (TNF receptor superfamily, member 6), APT1, CD95, FAS1, APO-1, FASTM, ALPS1A, TNFRSF6 | |
Background | It is now widely accepted that apoptosis plays an important role in the selection of immature thymocytes and Ag-primed peripheral T cells. Fas (also known as CD95/APO-1) is a cell surface protein belonging to the tumor necrosis factor receptor superfamily, which is expressed in a variety of normal and neoplastic cells. Binding of FasL to Fas or crosslinking of Fas by anti-Fas monoclonal antibodies results in rapid induction of apoptosis in Fas expressing cells. Clone ZB4 is known as Fas blocking, Fas neutralizing or Fas antagonistic antibody, whereas anti-Fas antibody (clone CH-11) is known as the agonistic antibody. | |
Related products | SY-001 Anti-Fas (CD95) (Human) mAb MD-10-3 Anti-Fas (CD95) (Human) mAb MD-10-4 Anti-Fas (CD95) (Human) mAb-FITC MD-10-5 Anti-Fas (CD95) (Human) mAb-PE |
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Product category | Research area:Apoptosis Cell surface antigens | |
Citations |
Western Blotting
Neutralization
Function
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