Antibody detailed product information

Code No. M181-3
Anti-KDEL mAb
Price ¥27,500
Size 100 µL (1 mg/mL)
Availability (in Japan) 10 or more
（In Japan at 17:00, Apr 18, 2024 in JST）
Clonality Monoclonal
Clone 1D5
Isotype
(Immunized Animal) 		Mouse IgG2aκ
Applications WB　0.1 µg/mL  
IP*　reported.  （PMID: 21072203）
IC　
IH*　reported.  （PMID: 19760141）
IF*　reported.  
Other(In Situ PLA)　reported.  （PMID: 32901097）
Immunogen
(Antigen)		 Mouse GRP78 C-terminal 644-655 aa
Reactivity [Gene ID]

Human, Mouse, Rat, Hamster, Fruit fly*(PMID: 23318643)
Storage buffer 1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp. -20°C
Conjugate Unlabeled
Manufacturer MBL
Background The KDEL (lys-asp-glu-leu) sequence is most common endoplasmic reticulum (ER) retention signal. The ER resident proteins, which should be located in the ER, have this retention motif, and this retention is mediated by KDEL receptor.
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M179-3 Anti-GM130 mAb
PM061 Anti-GM130 pAb
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Product category Tools:Others
Data


Citations

Western Blotting

  1. Xiang Y et al. Lactic acid induces aberrant amyloid precursor protein processing by promoting its interaction with endoplasmic reticulum chaperone proteins. PLoS One. 5, e13820 (2010)(PMID:21072203)
  2. Yagyu K et al. Activation of protein kinase R in the manganese-induced apoptosis of PC12 cells. Toxicology. 442, 152526 (2020)(PMID:32574669)

Immunoprecipitation

  1. Xiang Y et al. Lactic acid induces aberrant amyloid precursor protein processing by promoting its interaction with endoplasmic reticulum chaperone proteins. PLoS One. 5, e13820 (2010)(PMID:21072203)

Immunocytochemistry

  1. Xiang Y et al. Lactic acid induces aberrant amyloid precursor protein processing by promoting its interaction with endoplasmic reticulum chaperone proteins. PLoS One. 5, e13820 (2010)(PMID:21072203)
  2. Zhang B et al. Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of α1-antitrypsin. Blood 118, 3384-91 (2011)(PMID:21795745)
  3. van de Hoef DL et al. FKBP14 is an essential gene that regulates Presenilin protein levels and Notch signaling in Drosophila. Development 140, 810-9 (2013)(PMID:23318643)
  4. Zhao C et al. Mice lacking the intracellular cation channel TRIC-B have compromised collagen production and impaired bone mineralization. Sci Signal. 9, ra49 (2016)(PMID:27188440)

Immunohistochemistry

  1. Hino S et al. Regulation of ER molecular chaperone prevents bone loss in a murine model for osteoporosis. J Bone Miner Metab. 28, 131-8 (2010)(PMID:19760141)
  2. Furuichi T et al. ENU-induced missense mutation in the C-propeptide coding region of Col2a1 creates a mouse model of platyspondylic lethal skeletal dysplasia, Torrance type. Mamm Genome. 22, 318-28 (2011)(PMID:21538020)

Immunofluorescence

  1. Naoto Matsumoto N et al. PP1C and PP2A are p70S6K Phosphatases Whose Inhibition Ameliorates HLD12-Associated Inhibition of Oligodendroglial Cell Morphological Differentiation. Biomedicines. 8, 89 (2020)(PMID:32316234)
  2. Ninagawa S et al. Antipsychotic olanzapine-induced misfolding of proinsulin in the endoplasmic reticulum accounts for atypical development of diabetes. Elife. 9, e60970 (2020)(PMID:33198886)

ELISA

  1. Nakanishi K et al. Plant-derived secretory component forms secretory IgA with shiga toxin 1-specific dimeric IgA produced by mouse cells and whole plants. Plant Cell Rep. 38, 161-172 (2019)(PMID:30506369)

Other(In Situ PLA)

  1. Yoshimoto S et al. NFAT5 promotes oral squamous cell carcinoma progression in a hyperosmotic environment. Lab Invest. 101, 38-50 (2021)(PMID:32901097)
  • The availability is based on the information in Japan at 17:00, Apr 18, 2024 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications：
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.
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