Antibody detailed product information

Code No. M176-A48
Anti-EEA1 mAb-Alexa Fluor™ 488
Price ¥63,800
Size 100 µL (1 mg/mL)
Availability (in Japan) 1-9
（In Japan at 00:05, Apr 25, 2024 in JST）
Clonality Monoclonal
Clone 3C10
Isotype
(Immunized Animal) 		Mouse IgG2aκ
Applications IC　10 µg/mL  
Immunogen
(Antigen)		 Human EEA1, N-terminal synthetic peptide
Reactivity [Gene ID]

Human[8411], Mouse[216238], Rat[314764]
Storage buffer 1 mg/mL in PBS/1% BSA/0.1% ProClin 150
Storage temp. 4°C
Conjugate Alexa Fluor® 488
Manufacturer MBL
Background The early endosome is a cellular compartment inside eukaryotic cells. It is receiving endocytosed material and sorting them for vesicular transport to late endosomes and lysosomes or for recycling to the plasma membrane. EEA1 (Early Endosome Antigen1) is a 170 kDa coiled-coil protein, which is required for vesicular transport of proteins through early endosomes. It binds membrane lipids through its FYVE domain.
Related products M176-3 Anti-EEA1 mAb
M176-A59 Anti-EEA1 mAb-Alexa Fluor™ 594
M176-A64 Anti-EEA1 mAb-Alexa Fluor™ 647
PM062 Anti-EEA1 pAb
Product category Tools:Others
Data

Citations
  1. Rothmeier AS et al. Identification of the integrin-binding site on coagulation factor VIIa required for proangiogenic PAR2 signaling. Blood 131, 674-685 (2018)(PMID:29246902)

Immunocytochemistry

  1. Nishiumi E et al. fIntracellular fate of Ureaplasma parvum entrapped by host cellular autophagy. MicrobiologyOpen. 6, e441 (2017)(PMID:28088841)
  2. Kobayashi T et al. Lysosome biogenesis regulated by the amino-acid transporter SLC15A4 is critical for functional integrity of mast cells. Int Immunol. 29, 551-566 (2017)(PMID:29155995)
  • The availability is based on the information in Japan at 00:05, Apr 25, 2024 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications：
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.
MBLCopyright (C)2015 Medical ＆ Biological Laboratories Co., Ltd. All Rights Reserve