Code No. | M150-3 |
![]() |
Anti-Atg16L mAb | ||
Price | ¥48,000 | |
Special price |
¥33,600 (ends 2020/03/31) |
|
Size | 100 µg/100 µL | |
Availability (in Japan) | 10 or more
(In Japan at 17:00, Dec 11, 2019 in JST) |
|
Clonality | Monoclonal | |
Clone | 1F12 | |
Isotype (Immunized Animal) |
Mouse IgG1 κ | |
Applications | WB 1 µg/mL FCM* reported. (PMID: 25597631) IH* reported. (PMID: 24089213) |
|
Immunogen (Antigen) |
Recombinant Human ATG16L1 TV2 (85-588 a.a.) | |
Reactivity [Gene ID] | ||
Storage buffer | 1 mg/mL in PBS/50% glycerol, pH 7.2 | |
Storage temp. | -20°C | |
Conjugate | Unlabeled | |
Manufacturer | MBL | |
Alternative names | ATG16L1, autophagy related 16-like 1 (S. cerevisiae), IBD10, WDR30, APG16L, ATG16A, Apg16l | |
Background | Autophagy is a process of intracellular bulk degradation in which cytoplasmic components including organelles are sequestered within double-membrane vesicles that deliver the contents to the lysosome/vacuole for degradation. Autophagy has two ubiquitin-like conjugation systems, the Atg12 and LC3-II systems. In the Atg12 conjugation system, the Atg16L-Atg12-Atg5 forms 800 kDa complex that elongates autophagic isolation membrane. After completion of the formation of the autophagosome, the Atg12-Atg5-Atg16L complex dissociates from the membrane. In recent study, nonsynonymous SNP analysis has indicated that ATG16L1 is a Crohn's disease susceptibility gene. | |
Related products | 8485 Autophagy Ab Sampler Set PM040 Anti-Atg16L pAb M151-3 Anti-Atg10 (Human) mAb M154-3 Anti-Atg12 (Human) mAb M153-3 Anti-Atg5 mAb PM050 Anti-Atg5 pAb PM036 Anti-LC3 pAb M152-3 Anti-LC3 mAb PD017 Anti-Beclin 1 pAb PM072 Anti-VMP1 pAb PM045 Anti-p62 (SQSTM1) pAb PM040MS Anti-Atg16L pAb for My select sampler set M133-3 Anti-Atg3 mAb PM039 Anti-Atg7 (Human) pAb |
|
Product category | Research area:Autophagy Brands: |
|
Data | ||
Citations | Western Blotting
Flow Cytometry
Immunocytochemistry
Immunohistochemistry
Immunofluorescence
|